Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation

por Martin, Leenus, Rainey, Michael, Santocanale, Corrado, Gardner, Lawrence B.
Publicado 2011

DNA mediated chromatin pull-down for the study of chromatin replication

por Kliszczak, Anna E., Rainey, Michael D., Harhen, Brendan, Boisvert, Francois M., Santocanale, Corrado
Publicado 2011

PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors

por Göder, Anja, Quinlan, Aisling, Rainey, Michael D., Bennett, Declan, Shamavu, Daniel, Corso, Jacqueline, Santocanale, Corrado
Publicado 2023

Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint

por O'Connor, Aisling, Maffini, Stefano, Rainey, Michael D., Kaczmarczyk, Agnieszka, Gaboriau, David, Musacchio, Andrea, Santocanale, Corrado
Publicado 2015

CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage

por Rainey, Michael D, Quinlan, Aisling, Cazzaniga, Chiara, Mijic, Sofija, Martella, Oliviano, Krietsch, Jana, Göder, Anja, Lopes, Massimo, Santocanale, Corrado
Publicado 2020

DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach

por Wu, Kevin Z. L., Wang, Guan-Nan, Fitzgerald, Jennifer, Quachthithu, Huong, Rainey, Michael D., Cattaneo, Angela, Bachi, Angela, Santocanale, Corrado
Publicado 2016

Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models

por Natoni, Alessandro, Coyne, Mark R. E., Jacobsen, Alan, Rainey, Michael D., O’Brien, Gemma, Healy, Sandra, Montagnoli, Alessia, Moll, Jürgen, O’Dwyer, Michael, Santocanale, Corrado
Publicado 2013

A High Through-Put Screen for Small Molecules Modulating MCM2 Phosphorylation Identifies Ryuvidine as an Inducer of the DNA Damage Response

por FitzGerald, Jennifer, Murillo, Laura S., O'Brien, Gemma, O'Connell, Enda, O'Connor, Aisling, Wu, Kevin, Wang, Guan-Nan, Rainey, Michael D., Natoni, Alessandro, Healy, Sandra, O'Dwyer, Michael, Santocanale, Corrado
Publicado 2014