Fine-mapping of Parkinson’s disease susceptibility loci identifies putative causal variants

por Schilder, Brian M, Raj, Towfique
Publicado 2021

On the inclusion of self regulating branching processes in the working paradigm of evolutionary and population genetics

por Mode, Charles J., Sleeman, Candace K., Raj, Towfique
Publicado 2013

Prioritizing Parkinson’s disease genes using population-scale transcriptomic data

por Li, Yang I., Wong, Garrett, Humphrey, Jack, Raj, Towfique
Publicado 2019

Phenome-wide and expression quantitative trait locus associations of coronavirus disease 2019 genetic risk loci

por Moon, Chang Yoon, Schilder, Brian M., Raj, Towfique, Huang, Kuan-lin
Publicado 2021

Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain

por Vialle, Ricardo A., de Paiva Lopes, Katia, Bennett, David A., Crary, John F., Raj, Towfique
Publicado 2022

Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs

por Ramdhani, Satesh, Navarro, Elisa, Udine, Evan, Efthymiou, Anastasia G., Schilder, Brian M., Parks, Madison, Goate, Alison, Raj, Towfique
Publicado 2020

High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development

por Hefti, Marco M., Farrell, Kurt, Kim, SoongHo, Bowles, Kathryn R., Fowkes, Mary E., Raj, Towfique, Crary, John F.
Publicado 2018

Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

por Hutchinson, John N., Raj, Towfique, Fagerness, Jes, Stahl, Eli, Viloria, Fernando T., Gimelbrant, Alexander, Seddon, Johanna, Daly, Mark, Chess, Andrew, Plenge, Robert
Publicado 2014

Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes

por Fodder, Katherine, Murthy, Megha, Rizzu, Patrizia, Toomey, Christina E., Hasan, Rahat, Humphrey, Jack, Raj, Towfique, Lunnon, Katie, Mill, Jonathan, Heutink, Peter, Lashley, Tammaryn, Bettencourt, Conceição
Publicado 2023

Sex-biased genetic effects on gene regulation in humans

por Dimas, Antigone S., Nica, Alexandra C., Montgomery, Stephen B., Stranger, Barbara E., Raj, Towfique, Buil, Alfonso, Giger, Thomas, Lappalainen, Tuuli, Gutierrez-Arcelus, Maria, McCarthy, Mark I., Dermitzakis, Emmanouil T.
Publicado 2012

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing

por Bampton, Alexander, Gatt, Ariana, Humphrey, Jack, Cappelli, Sara, Bhattacharya, Dipanjan, Foti, Sandrine, Brown, Anna-Leigh, Asi, Yasmine, Low, Yi Hua, Foiani, Marco, Raj, Towfique, Buratti, Emanuele, Fratta, Pietro, Lashley, Tammaryn
Publicado 2021

Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence

por Gokcumen, Omer, Zhu, Qihui, Mulder, Lubbertus C. F., Iskow, Rebecca C., Austermann, Christian, Scharer, Christopher D., Raj, Towfique, Boss, Jeremy M., Sunyaev, Shamil, Price, Alkes, Stranger, Barbara, Simon, Viviana, Lee, Charles
Publicado 2013

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4(+) Effector Memory T Cells

por Hu, Xinli, Kim, Hyun, Raj, Towfique, Brennan, Patrick J., Trynka, Gosia, Teslovich, Nikola, Slowikowski, Kamil, Chen, Wei-Min, Onengut, Suna, Baecher-Allan, Clare, De Jager, Philip L., Rich, Stephen S., Stranger, Barbara E., Brenner, Michael B., Raychaudhuri, Soumya
Publicado 2014

Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

por Chibnik, Lori B, White, Charles C, Mukherjee, Shubhabrata, Raj, Towfique, Yu, Lei, Larson, Eric B., Montine, Thomas J., Keene, C. Dirk, Sonnen, Joshua, Schneider, Julie A., Crane, Paul K., Shulman, Joshua M., Bennett, David A, De Jager, Philip L
Publicado 2017

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility

por Raj, Towfique, Li, Yang I., Wong, Garrett, Humphrey, Jack, Wang, Minghui, Ramdhani, Satesh, Wang, Ying-Chih, Ng, Bernard, Gupta, Ishaan, Haroutunian, Vahram, Schadt, Eric E., Young-Pearse, Tracy, Mostafavi, Sara, Zhang, Bin, Sklar, Pamela, Bennett, David A., De Jager, Philip L.
Publicado 2018

Patterns of Cis Regulatory Variation in Diverse Human Populations

por Stranger, Barbara E., Montgomery, Stephen B., Dimas, Antigone S., Parts, Leopold, Stegle, Oliver, Ingle, Catherine E., Sekowska, Magda, Smith, George Davey, Evans, David, Gutierrez-Arcelus, Maria, Price, Alkes, Raj, Towfique, Nisbett, James, Nica, Alexandra C., Beazley, Claude, Durbin, Richard, Deloukas, Panos, Dermitzakis, Emmanouil T.
Publicado 2012

CD33 Alzheimer’s disease locus: Altered monocyte function and amyloid biology

por Bradshaw, Elizabeth M, Chibnik, Lori B, Keenan, Brendan T, Ottoboni, Linda, Raj, Towfique, Tang, Anna, Rosenkrantz, Laura L, Imboywa, Selina, Lee, Michelle, Von Korff, Alina, Morris, Martha C, Evans, Denis A, Johnson, Keith, Sperling, Reisa A, Schneider, Julie A, Bennett, David A, De Jager, Philip L
Publicado 2013

Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation

por Croteau-Chonka, Damien C., Rogers, Angela J., Raj, Towfique, McGeachie, Michael J., Qiu, Weiliang, Ziniti, John P., Stubbs, Benjamin J., Liang, Liming, Martinez, Fernando D., Strunk, Robert C., Lemanske, Robert F., Liu, Andrew H., Stranger, Barbara E., Carey, Vincent J., Raby, Benjamin A.
Publicado 2015

Genetic architecture of age-related cognitive decline in African Americans

por Raj, Towfique, Chibnik, Lori B., McCabe, Cristin, Wong, Andus, Replogle, Joseph M., Yu, Lei, Gao, Sujuan, Unverzagt, Frederick W., Stranger, Barbara, Murrell, Jill, Barnes, Lisa, Hendrie, Hugh C., Foroud, Tatiana, Krichevsky, Anna, Bennett, David A., Hall, Kathleen S., Evans, Denis A., De Jager, Philip L.
Publicado 2016

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

por Patsopoulos, Nikolaos A., Barcellos, Lisa F., Hintzen, Rogier Q., Schaefer, Catherine, van Duijn, Cornelia M., Noble, Janelle A., Raj, Towfique, Gourraud, Pierre-Antoine, Stranger, Barbara E., Oksenberg, Jorge, Olsson, Tomas, Taylor, Bruce V., Sawcer, Stephen, Hafler, David A., Carrington, Mary, De Jager, Philip L., de Bakker, Paul I. W.
Publicado 2013