STAT5b in LGL leukemia – a novel therapeutic target?

por Rajala, Hanna L. M., Mustjoki, Satu
Publicado 2013

A novel class of somatic mutations in blood detected preferentially in CD8 + cells

por Valori, Miko, Jansson, Lilja, Kiviharju, Anna, Ellonen, Pekka, Rajala, Hanna, Awad, Shady Adnan, Mustjoki, Satu, Tienari, Pentti J.
Publicado 2017

Gemtuzumab-Ozogamicin-Related Impaired Hemoglobin-Haptoglobin Scavenging as On-Target/Off-Tumor Toxicity of Anti-CD33 AML Therapy: A Report of Two Cases

por Rajala, Hanna L. M., Anttila, Veli-Jukka, Haapio, Mikko, Keränen, Mikko A. I., Wartiovaara-Kautto, Ulla, Räty, Riikka
Publicado 2021

STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation

por Kim, Daehong, Park, Giljun, Huuhtanen, Jani, Ghimire, Bishwa, Rajala, Hanna, Moriggl, Richard, Chan, Wing C., Kankainen, Matti, Myllymäki, Mikko, Mustjoki, Satu
Publicado 2021

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

por Kuusanmäki, Heikki, Dufva, Olli, Parri, Elina, van Adrichem, Arjan J., Rajala, Hanna, Majumder, Muntasir M., Yadav, Bhagwan, Parsons, Alun, Chan, Wing C., Wennerberg, Krister, Mustjoki, Satu, Heckman, Caroline A.
Publicado 2017

Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease

por Keskitalo, Salla, Haapaniemi, Emma M., Glumoff, Virpi, Liu, Xiaonan, Lehtinen, Ville, Fogarty, Christopher, Rajala, Hanna, Chiang, Samuel C., Mustjoki, Satu, Kovanen, Panu, Lohi, Jouko, Bryceson, Yenan T., Seppänen, Mikko, Kere, Juha, Heiskanen, Kaarina, Varjosalo, Markku
Publicado 2019

Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia

por Lundgren, Sofie, Keränen, Mikko A. I., Kankainen, Matti, Huuhtanen, Jani, Walldin, Gunilla, Kerr, Cassandra M., Clemente, Michael, Ebeling, Freja, Rajala, Hanna, Brück, Oscar, Lähdesmäki, Harri, Hannula, Sari, Hannunen, Tiina, Ellonen, Pekka, Young, Neal S., Ogawa, Seishi, Maciejewski, Jaroslaw P., Hellström-Lindberg, Eva, Mustjoki, Satu
Publicado 2021

Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8(+) T-cell large granular lymphocytic leukemia

por Huuhtanen, Jani, Bhattacharya, Dipabarna, Lönnberg, Tapio, Kankainen, Matti, Kerr, Cassandra, Theodoropoulos, Jason, Rajala, Hanna, Gurnari, Carmelo, Kasanen, Tiina, Braun, Till, Teramo, Antonella, Zambello, Renato, Herling, Marco, Ishida, Fumihiro, Kawakami, Toru, Salmi, Marko, Loughran, Thomas, Maciejewski, Jaroslaw P., Lähdesmäki, Harri, Kelkka, Tiina, Mustjoki, Satu
Publicado 2022

S176: FUNCTIONAL AND ANTIGEN-SPECIFIC CHARACTERIZATION OF IMMUNE CELLS AT THE SINGLE-CELL LEVEL REVEALS CONVERGENCE OF ADAPTIVE AND INNATE IMMUNITY IN IMMUNE APLASTIC ANEMIA

por Huuhtanen, Jani, Lundgren, Sofie, Keränen, Mikko, Feng, Xingim, Dulau-Florea, Alina, Patel, Bhavisha, Zaimoku, Yoshitaka, Kerr, Cassandra, Jokinen, Emmi, Heinonen, Markus, Rajala, Hanna, Siitonen, Sanna, Ebeling, Freja, Ryland, Georgina, Fox, Lucy, Blombery, Piers, Hellström-Lindberg, Eva, Maciejewski, Jaroslaw P., Young, Neal S., Lähdesmäki, Harri, Mustjoki, Satu
Publicado 2023

Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia

por Kelkka, Tiina, Tyster, Mikko, Lundgren, Sofie, Feng, Xingmin, Kerr, Cassandra, Hosokawa, Kohei, Huuhtanen, Jani, Keränen, Mikko, Patel, Bhavisha, Kawakami, Toru, Maeda, Yuka, Nieminen, Otso, Kasanen, Tiina, Aronen, Pasi, Yadav, Bhagwan, Rajala, Hanna, Nakazawa, Hideyuki, Jaatinen, Taina, Hellström-Lindberg, Eva, Ogawa, Seishi, Ishida, Fumihiro, Nishikawa, Hiroyoshi, Nakao, Shinji, Maciejewski, Jaroslaw, Young, Neal S., Mustjoki, Satu
Publicado 2022

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

por Flanagan, Sarah E., Haapaniemi, Emma, Russell, Mark A., Caswell, Richard, Allen, Hana Lango, De Franco, Elisa, McDonald, Timothy J., Rajala, Hanna, Ramelius, Anita, Barton, John, Heiskanen, Kaarina, Heiskanen-Kosma, Tarja, Kajosaari, Merja, Murphy, Nuala P., Milenkovic, Tatjana, Seppänen, Mikko, Lernmark, Åke, Mustjoki, Satu, Otonkoski, Timo, Kere, Juha, Morgan, Noel G., Ellard, Sian, Hattersley, Andrew T.
Publicado 2014