Triptonide Modulates MAPK Signaling Pathways and Exerts Anticancer Effects via ER Stress-Mediated Apoptosis Induction in Human Osteosarcoma Cells

por Zheng, Liyun, Fang, Shiji, Hui, Junguo, Rajamanickam, Vinothkumar, Chen, Minjiang, Weng, Qiaoyou, Wu, Xulu, Zhao, Zhongwei, Ji, Jiansong
Publicado 2020

Indole-2-Carboxamide Derivative LG25 Inhibits Triple-Negative Breast Cancer Growth By Suppressing Akt/mTOR/NF-κB Signalling Pathway

por Xu, Xiaohong, Rajamanickam, Vinothkumar, Shu, Sheng, Liu, Zhoudi, Yan, Tao, He, Jinxin, Liu, Zhiguo, Guo, Guilong, Liang, Guang, Wang, Yi
Publicado 2019

Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis

por Rajamanickam, Vinothkumar, Yan, Tao, Xu, Shanmei, Hui, Junguo, Xu, Xiaohong, Ren, Luqing, Liu, Zhoudi, Liang, Guang, Wang, Ouchen, Wang, Yi
Publicado 2020

Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and lung metastasis: Erratum

por Rajamanickam, Vinothkumar, Yan, Tao, Xu, Shanmei, Hui, Junguo, Xu, Xiaohong, Ren, Luqing, Liu, Zhoudi, Liang, Guang, Wang, Ouchen, Wang, Yi
Publicado 2022

Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells

por Chen, Xi, Chen, Xiaoming, Zhang, Xi, Wang, Li, Cao, Peihai, Rajamanickam, Vinothkumar, Wu, Chao, Zhou, Huiping, Cai, Yuepiao, Liang, Guang, Wang, Yi
Publicado 2018

Allylated Curcumin Analog CA6 Inhibits TrxR1 and Leads to ROS-Dependent Apoptotic Cell Death in Gastric Cancer Through Akt-FoxO3a

por Rajamanickam, Vinothkumar, Yan, Tao, Wu, Liangrong, Zhao, Yanni, Xu, Xiaohong, Zhu, Heping, Chen, Xi, Wang, Meihong, Liu, Zhoudi, Liu, Zhiguo, Liang, Guang, Wang, Yi
Publicado 2020

Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant—Antioxidant Balance

por Kumar, Narendra, Rachagani, Satyanarayana, Natarajan, Gopalakrishnan, Crook, Alexandra, Gopal, Thiyagarajan, Rajamanickam, Vinothkumar, Kaushal, Jyoti B., Nagabhishek, Sirpu N., Powers, Robert, Batra, Surinder K., Saraswathi, Viswanathan
Publicado 2023

Alantolactone promotes ER stress‐mediated apoptosis by inhibition of TrxR1 in triple‐negative breast cancer cell lines and in a mouse model

por Yin, Changtian, Dai, Xuanxuan, Huang, Xiangjie, Zhu, Wangyu, Chen, Xi, Zhou, Qiulin, Wang, Canwei, Zhao, Chengguang, Zou, Peng, Liang, Guang, Rajamanickam, Vinothkumar, Wang, Ouchen, Zhang, Xiaohua, Cui, Ri
Publicado 2019

Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3

por Rajamanickam, Vinothkumar, Zhu, Heping, Feng, Chen, Chen, Xi, Zheng, Hailun, Xu, Xiaohong, Zhang, Qianqian, Zou, Peng, He, Guodong, Dai, Xuanxuan, Yang, Xi, Wang, Yi, Liu, Zhiguo, Liang, Guang, Guo, Guilong
Publicado 2017