Transcriptomic profiling of human skin biopsies in the clinical trial setting: A protocol for high quality RNA extraction from skin tumours

por Danilenko, Marina, Stones, Robert, Rajan, Neil
Publicado 2018

Infiltrative Recurrent Eccrine Spiradenoma of the Anterior Neck Treated Using Mohs Micrographic Surgery

por Rahim, Rajib R, Rajan, Neil, Langtry, James AA
Publicado 2013

<i>CYLD</i> GeneticTesting for Brooke-Spiegler Syndrome, Familial Cylindromatosis and Multiple Familial Trichoepitheliomas

por Dubois, Anna, Wilson, Valerie, Bourn, David, Rajan, Neil
Publicado 2015

p63 and smooth muscle actin expression in low‐grade spiradenocarcinomas in a case of CYLD cutaneous syndrome

por Hoyle, Aoisha, Davies, Kerry, Rajan, Neil, Melly, Lucy
Publicado 2018

Genetic Testing in CYLD Cutaneous Syndrome: An Update

por Nagy, Nikoletta, Dubois, Anna, Szell, Marta, Rajan, Neil
Publicado 2021

Hypohidrotic ectodermal dysplasia and juxtaclavicular beaded lines

por Dubois, Anna, Fostier, William, Sampson, James, Durham, Justin, Rajan, Neil
Publicado 2022

Tracking tumor kinetics in patients with germline CYLD mutations

por Brown, Sarah, Worthy, Sylvia A., Langtry, James A.A., Rajan, Neil
Publicado 2018

CYLD in health and disease

por Marín-Rubio, José L., Raote, Ishier, Inns, Joseph, Dobson-Stone, Carol, Rajan, Neil
Publicado 2023

Development and validation of LC–MS/MS with in-source collision-induced dissociation for the quantification of pegcantratinib in human skin tumors

por Zangarini, Monique, Rajan, Neil, Danilenko, Marina, Berry, Philip, Traversa, Silvio, Veal, Gareth J
Publicado 2017

The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate Notch signalling

por Rajan, Neil, Elliott, Richard J.R., Smith, Alice, Sinclair, Naomi, Swift, Sally, Lord, Christopher J., Ashworth, Alan
Publicado 2014

Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours:...

por Cranston, Amy, Stocken, Deborah D., Stamp, Elaine, Roblin, David, Hamlin, Julia, Langtry, James, Plummer, Ruth, Ashworth, Alan, Burn, John, Rajan, Neil
Publicado 2017

Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome

por Davies, Helen R., Hodgson, Kirsty, Schwalbe, Edward, Coxhead, Jonathan, Sinclair, Naomi, Zou, Xueqing, Cockell, Simon, Husain, Akhtar, Nik-Zainal, Serena, Rajan, Neil
Publicado 2019

Dysregulated TRK Signalling is a Therapeutic Target in CYLD Defective Tumours

por Rajan, Neil, Elliott, Richard, Clewes, Oliver, Mackay, Alan, Reis-Filho, Jorge S., Burn, John, Langtry, James, Sieber-Blum, Maya, Lord, Christopher J., Ashworth, Alan
Publicado 2011

Overexpression of MYB drives proliferation of CYLD‐defective cylindroma cells

por Rajan, Neil, Andersson, Mattias K, Sinclair, Naomi, Fehr, André, Hodgson, Kirsty, Lord, Christopher J, Kazakov, Dmitry V, Vanecek, Tomas, Ashworth, Alan, Stenman, Göran
Publicado 2016

Diverse presentations of cutaneous mosaicism occur in CYLD cutaneous syndrome and may result in parent-to-child transmission

por Arefi, Majid, Wilson, Valerie, Muthiah, Siobhan, Zwolinski, Simon, Bajwa, Dalvir, Brennan, Paul, Blasdale, Katie, Bourn, David, Burn, John, Santibanez-Koref, Mauro, Rajan, Neil
Publicado 2019

Immune-related adverse events in checkpoint blockade: Observations from human tissue and therapeutic considerations

por Williams, Kristian C., Gault, Abigail, Anderson, Amy E., Stewart, Christopher J., Lamb, Christopher A., Speight, R. Ally, Rajan, Neil, Plummer, Ruth, Pratt, Arthur G.
Publicado 2023

Targeting Tropomyosin Receptor Kinase in Cutaneous CYLD Defective Tumors With Pegcantratinib: The TRAC Randomized Clinical Trial

por Danilenko, Marina, Stamp, Elaine, Stocken, Deborah D., Husain, Akhtar, Zangarini, Monique, Cranston, Amy, Stones, Robert, Sinclair, Naomi, Hodgson, Kirsty, Bowett, Susan A., Roblin, David, Traversa, Silvio, Plummer, Ruth, Veal, Gareth, Langtry, James A. A., Ashworth, Alan, Burn, John, Rajan, Neil
Publicado 2018

Seventh BHD international symposium: recent scientific and clinical advancement

por Woodford, Mark R., Andreou, Avgi, Baba, Masaya, van de Beek, Irma, Di Malta, Chiara, Glykofridis, Iris, Grimes, Hannah, Henske, Elizabeth P., Iliopoulos, Othon, Kurihara, Masatoshi, Lazor, Romain, Linehan, W. Marston, Matsumoto, Kenki, Marciniak, Stefan J., Namba, Yukiko, Pause, Arnim, Rajan, Neil, Ray, Anindita, Schmidt, Laura S., Shi, Wei, Steinlein, Ortrud K., Thierauf, Julia, Zoncu, Roberto, Webb, Anna, Mollapour, Mehdi
Publicado 2022

PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma

por Polubothu, Satyamaanasa, Bender, Nicole, Muthiah, Siobhan, Zecchin, Davide, Demetriou, Charalambos, Martin, Sara Barberan, Malhotra, Sony, Travnickova, Jana, Zeng, Zhiqiang, Böhm, Markus, Barbarot, Sebastien, Cottrell, Catherine, Davies, Olivia, Baselga, Eulalia, Burrows, Nigel P., Carmignac, Virginie, Diaz, Joey Santiago, Fink, Christine, Haenssle, Holger A., Happle, Rudolf, Harland, Mark, Majerowski, Jacquelyn, Vabres, Pierre, Vincent, Marie, Newton-Bishop, Julia A., Bishop, D. Tim, Siegel, Dawn, Patton, E. Elizabeth, Topf, Maya, Rajan, Neil, Drolet, Beth, Kinsler, Veronica A.
Publicado 2023