Exercise, Nrf2 and Antioxidant Signaling in Cardiac Aging

por Narasimhan, Madhusudhanan, Rajasekaran, Namakkal S.
Publicado 2016

Redox Signaling and the Cardiovascular and Skeletal Muscle System

por Gomes, Aldrin V., Rajasekaran, Namakkal S., Pi, Xinchun
Publicado 2015

Editorial: Metabolic and Redox Regulation at the Center of Aging

por Shiva, Sruti, Rajasekaran, Namakkal-Soorappan, Hill, Bradford G.
Publicado 2022

Activation of EP4 receptor limits transition of acute to chronic heart failure in lipoxygenase deficient mice

por Kain, Vasundhara, Ingle, Kevin A., Rajasekaran, Namakkal S., Halade, Ganesh V.
Publicado 2021

Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium

por Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Tamowski, Susan, Darley-Usmar, Victor, Rajasekaran, Namakkal S.
Publicado 2017

Reductive stress impairs myogenic differentiation

por Rajasekaran, Namakkal S., Shelar, Sandeep Balu, Jones, Dean P., Hoidal, John R.
Publicado 2020

Identification of transcriptome signature for myocardial reductive stress

por Quiles, Justin M., Narasimhan, Madhusudhanan, Mosbruger, Timothy, Shanmugam, Gobinath, Crossman, David, Rajasekaran, Namakkal S.
Publicado 2017

Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

por Quiles, Justin M., Narasimhan, Madhusudhanan, Shanmugam, Gobinath, Milash, Brett, Hoidal, John R., Rajasekaran, Namakkal S.
Publicado 2017

Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy

por Sunny, Sini, Jyothidasan, Arun, David, Cynthia L., Parsawar, Krishna, Veerappan, Arul, Jones, Dean P., Pogwizd, Steven, Rajasekaran, Namakkal S.
Publicado 2022

Evidence for a hyper-reductive redox in a sub-set of heart failure patients

por Sairam, Thiagarajan, Patel, Amit N., Subrahmanian, Meenu, Gopalan, Rajendiran, Pogwizd, Steven M., Ramalingam, Sudha, Sankaran, Ramalingam, Rajasekaran, Namakkal Soorapan
Publicado 2018

Reductive stress promotes protein aggregation and impairs neurogenesis

por S Narasimhan, Kishore Kumar, Devarajan, Asokan, Karan, Goutam, Sundaram, Sandhya, Wang, Qin, van Groen, Thomas, Monte, Federica del, Rajasekaran, Namakkal S.
Publicado 2020

Exercise Mediated Nrf2 Signaling Protects the Myocardium From Isoproterenol-Induced Pathological Remodeling

por Shanmugam, Gobinath, Challa, Anil K., Devarajan, Asokan, Athmanathan, Baskaran, Litovsky, Silvio H., Krishnamurthy, Prasanna, Davidson, Christopher J., Rajasekaran, Namakkal Soorappan
Publicado 2019

Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling

por Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Conley, Robbie L., Sairam, Thiagarajan, Kumar, Ashutosh, Mason, Ronald P., Sankaran, Ramalingam, Hoidal, John R., Rajasekaran, Namakkal S.
Publicado 2017

Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice

por Shanmugam, Gobinath, Challa, Anil Kumar, Litovsky, Silvio H., Devarajan, Asokan, Wang, Ding, Jones, Dean P., Darley-Usmar, Victor M., Rajasekaran, Namakkal Soorappan
Publicado 2019

Transcriptional Regulation of Structural and Functional Adaptations in a Developing Adulthood Myocardium

por Sunny, Sini, Challa, Anil Kumar, Qiao, Aijun, Jyothidasan, Arun, Krishnamurthy, Prasanna, Ramamurthy, Muralidharan T, Crossman, David K, Pogwizd, Steven, Cinghu, Senthilkumar, Rajasekaran, Namakkal S
Publicado 2021

Transgenic Expression of Nrf2 Induces a Pro-Reductive Stress and Adaptive Cardiac Remodeling in the Mouse

por Jyothidasan, Arun, Sunny, Sini, Murugesan, Saravanakumar, Quiles, Justin M., Challa, Anil Kumar, Dalley, Brian, Cinghu, Senthil Kumar, Nanda, Vivek, Rajasekaran, Namakkal-Soorappan
Publicado 2022

The NADPH Metabolic Network Regulates Human αB-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster

por Xie, Heng B., Cammarato, Anthony, Rajasekaran, Namakkal S., Zhang, Huali, Suggs, Jennifer A., Lin, Ho-Chen, Bernstein, Sanford I., Benjamin, Ivor J., Golic, Kent G.
Publicado 2013

Morinda citrifolia and Its Active Principle Scopoletin Mitigate Protein Aggregation and Neuronal Apoptosis through Augmenting the DJ-1/Nrf2/ARE Signaling Pathway

por Narasimhan, Kishore Kumar S., Jayakumar, Deepthy, Velusamy, Prema, Srinivasan, Ashokkumar, Mohan, Thangarajeswari, Ravi, Divya Bhavani, Uthamaraman, Saraswathi, Sathyamoorthy, Yogesh Kanna, Rajasekaran, Namakkal Soorappan, Periandavan, Kalaiselvi
Publicado 2019

A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes

por Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Sakthivel, Ramasamy, Kumar R, Rajesh, Davidson, Christopher, Palaniappan, Sethu, Claycomb, William W., Hoidal, John R., Darley-Usmar, Victor M., Rajasekaran, Namakkal Soorappan
Publicado 2016

Impaired Transcriptional Activity of Nrf2 in Age-Related Myocardial Oxidative Stress Is Reversible by Moderate Exercise Training

por Gounder, Sellamuthu S., Kannan, Sankaranarayanan, Devadoss, Dinesh, Miller, Corey J., Whitehead, Kevin S., Odelberg, Shannon J., Firpo, Matthew A., Paine, Robert, Hoidal, John R., Abel, E. Dale, Rajasekaran, Namakkal S.
Publicado 2012