Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5′-triphosphate exposure to support posology for SARS-CoV-2

por Pertinez, Henry, Rajoli, Rajith K R, Khoo, Saye H, Owen, Andrew
Publicado 2021

Serum vitamin D level in patients with schizophrenia: A community-based study

por Rajith, K. Ravindren, Krishnakumar, Padinharath, Danish, Ekkalayil, Dhanasooraj, Dhananjayan, Ranjitha, M., Midhun, Sidharthan
Publicado 2022

Using mechanistic physiologically-based pharmacokinetic models to assess prenatal drug exposure: Thalidomide versus efavirenz as case studies

por Atoyebi, Shakir Adeyinka, Rajoli, Rajith K.R., Adejuyigbe, Ebunoluwa, Owen, Andrew, Bolaji, Oluseye, Siccardi, Marco, Olagunju, Adeniyi
Publicado 2019

Short Term Efficacy and Safety of Low Dose Tolvaptan in Patients with Acute Decompensated Heart Failure with Hyponatremia: A Prospective Observational Pilot Study from a Single Cen...

por Patra, Soumya, Kumar, Basant, Harlalka, Kaushal K., Jain, Apoorva, Bhanuprakash, H. M., Sadananda, K. S., Basappa, Harsha, Santhosh, K., Rajith, K. S., Bharathi, K. S., Manjunath, C. N.
Publicado 2014

Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters

por Gallardo-Toledo, Eduardo, Neary, Megan, Sharp, Joanne, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Curley, Paul, Arshad, Usman, Pertinez, Henry, Rajoli, Rajith K. R., Valentijn, Anthony, Cox, Helen, Tatham, Lee, Kipar, Anja, Stewart, James P., Owen, Andrew
Publicado 2023

Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters

por Neary, Megan, Sharp, Joanne, Gallardo-Toledo, Eduardo, Herriott, Joanne, Kijak, Edyta, Bramwell, Chloe, Cox, Helen, Tatham, Lee, Box, Helen, Curley, Paul, Arshad, Usman, Rajoli, Rajith K. R., Pertinez, Henry, Valentijn, Anthony, Dhaliwal, Kevin, Mc Caughan, Frank, Hobson, James, Rannard, Steve, Kipar, Anja, Stewart, James P., Owen, Andrew
Publicado 2023

Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics

por Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith K. R., Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steve P., O’Neill, Paul M., Aljayyoussi, Ghaith, Pennington, Shaun H., Ward, Stephen A., Hill, Andrew, Back, David J., Khoo, Saye H., Bray, Patrick G., Biagini, Giancarlo A., Owen, Andrew
Publicado 2020

Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis

por Rajoli, Rajith K. R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun H., Hill, Andrew, Boffito, Marta, Ward, Steve A., Khoo, Saye H., Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo A., Owen, Andrew
Publicado 2020

Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells

por Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Dias, Suelen S. G., Temerozo, Jairo R., Da Silva, Aline de Paula D., da Silva, Carine S., Blanco, Camilla, Ferreira, André C., Mattos, Mayara, Soares, Vinicius C., Pereira-Dutra, Filipe, Miranda, Milene Dias, Barreto-Vieira, Debora F., da Silva, Marcos Alexandre N., Santos, Suzana S., Torres, Mateo, Chaves, Otávio Augusto, Rajoli, Rajith K. R., Paccanaro, Alberto, Owen, Andrew, Bou-Habib, Dumith Chequer, Bozza, Patrícia T., Souza, Thiago Moreno L.
Publicado 2022

An Open Label, Adaptive, Phase 1 Trial of High‐Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS‐CoV‐2

por Walker, Lauren E., FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin, Rajoli, Rajith K. R., Else, Laura, Dilly‐Penchala, Sujan, Amara, Alieu, Lalloo, David G., Jacobs, Michael, Pertinez, Henry, Hatchard, Parys, Waugh, Robert, Lawrence, Megan, Johnson, Lucy, Fines, Keira, Reynolds, Helen, Rowland, Timothy, Crook, Rebecca, Okenyi, Emmanuel, Byrne, Kelly, Mozgunov, Pavel, Jaki, Thomas, Khoo, Saye, Owen, Andrew, Griffiths, Gareth, Fletcher, Thomas E.
Publicado 2021