Fast and efficient synaptosome isolation and post-synaptic density enrichment from hiPSC-motor neurons by biochemical sub-cellular fractionation

por Rajkumar, Sandeep, Böckers, Tobias M., Catanese, Alberto
Publicado 2023

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons

por Sommer, Daniel, Rajkumar, Sandeep, Seidel, Mira, Aly, Amr, Ludolph, Albert, Ho, Ritchie, Boeckers, Tobias M., Catanese, Alberto
Publicado 2022

Propranolol reduces the accumulation of cytotoxic aggregates in C9orf72-ALS/FTD in vitro models

por Seidel, Mira, Rajkumar, Sandeep, Steffke, Christina, Noeth, Vivien, Agarwal, Shreya, Roger, Kevin, Lipecka, Joanna, Ludolph, Albert, Guerrera, Chiara Ida, Boeckers, Tobias, Catanese, Alberto
Publicado 2023

Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis

por Catanese, Alberto, Rajkumar, Sandeep, Sommer, Daniel, Masrori, Pegah, Hersmus, Nicole, Van Damme, Philip, Witzel, Simon, Ludolph, Albert, Ho, Ritchie, Boeckers, Tobias M, Mulaw, Medhanie
Publicado 2023

Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

por Aly, Amr, Laszlo, Zsofia I., Rajkumar, Sandeep, Demir, Tugba, Hindley, Nicole, Lamont, Douglas J., Lehmann, Johannes, Seidel, Mira, Sommer, Daniel, Franz-Wachtel, Mirita, Barletta, Francesca, Heumos, Simon, Czemmel, Stefan, Kabashi, Edor, Ludolph, Albert, Boeckers, Tobias M., Henstridge, Christopher M., Catanese, Alberto
Publicado 2023

Correction to: Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

por Aly, Amr, Laszlo, Zsofia I., Rajkumar, Sandeep, Demir, Tugba, Hindley, Nicole, Lamont, Douglas J., Lehmann, Johannes, Seidel, Mira, Sommer, Daniel, Franz-Wachtel, Mirita, Barletta, Francesca, Heumos, Simon, Czemmel, Stefan, Kabashi, Edor, Ludolph, Albert, Boeckers, Tobias M., Henstridge, Christopher M., Catanese, Alberto
Publicado 2023

Synaptic disruption and CREB‐regulated transcription are restored by K(+) channel blockers in ALS

por Catanese, Alberto, Rajkumar, Sandeep, Sommer, Daniel, Freisem, Dennis, Wirth, Alexander, Aly, Amr, Massa‐López, David, Olivieri, Andrea, Torelli, Federica, Ioannidis, Valentin, Lipecka, Joanna, Guerrera, Ida Chiara, Zytnicki, Daniel, Ludolph, Albert, Kabashi, Edor, Mulaw, Medhanie A, Roselli, Francesco, Böckers, Tobias M
Publicado 2021