Mycobacterium tuberculosis WhiB3 Responds to Vacuolar pH-induced Changes in Mycothiol Redox Potential to Modulate Phagosomal Maturation and Virulence

por Mehta, Mansi, Rajmani, Raju S., Singh, Amit
Publicado 2016

PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection

por Borbora, Salik Miskat, Rajmani, Raju S., Balaji, Kithiganahalli Narayanaswamy
Publicado 2022

An allosteric inhibitor of Mycobacterium tuberculosis ArgJ: Implications to a novel combinatorial therapy

por Mishra, Archita, Mamidi, Ashalatha S, Rajmani, Raju S, Ray, Ananya, Roy, Rajanya, Surolia, Avadhesha
Publicado 2018

S-Adenosylmethionine–responsive cystathionine β-synthase modulates sulfur metabolism and redox balance in Mycobacterium tuberculosis

por Bandyopadhyay, Parijat, Pramanick, Ishika, Biswas, Rupam, PS, Sabarinath, Sreedharan, Sreesa, Singh, Shalini, Rajmani, Raju S., Laxman, Sunil, Dutta, Somnath, Singh, Amit
Publicado 2022

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions

por Mittal, Nidhi, Sengupta, Nayanika, Malladi, Sameer Kumar, Reddy, Poorvi, Bhat, Madhuraj, Rajmani, Raju S., Sedeyn, Koen, Saelens, Xavier, Dutta, Somnath, Varadarajan, Raghavan
Publicado 2021

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

por Prakhar, Praveen, Bhatt, Bharat, Lohia, Gaurav Kumar, Shah, Awantika, Mukherjee, Tanushree, Kolthur-Seetharam, Ullas, Sundaresan, Nagalingam R., Rajmani, Raju S., Balaji, Kithiganahalli Narayanaswamy
Publicado 2023

Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

por Mishra, Saurabh, Shukla, Prashant, Bhaskar, Ashima, Anand, Kushi, Baloni, Priyanka, Jha, Rajiv Kumar, Mohan, Abhilash, Rajmani, Raju S, Nagaraja, Valakunja, Chandra, Nagasuma, Singh, Amit
Publicado 2017

Neutralizing Efficacy of Encapsulin Nanoparticles against SARS-CoV2 Variants of Concern

por Khaleeq, Sara, Sengupta, Nayanika, Kumar, Sahil, Patel, Unnatiben Rajeshbhai, Rajmani, Raju S., Reddy, Poorvi, Pandey, Suman, Singh, Randhir, Dutta, Somnath, Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2023

Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo

por Tripathi, Ashutosh, Anand, Kushi, Das, Mayashree, O’Niel, Ruchika Annie, P. S, Sabarinath, Thakur, Chandrani, R. L., Raghunatha Reddy, Rajmani, Raju S., Chandra, Nagasuma, Laxman, Sunil, Singh, Amit
Publicado 2022

Identification of diphenylurea derivatives as novel endocytosis inhibitors that demonstrate broad-spectrum activity against SARS-CoV-2 and influenza A virus both in vitro and in vi...

por Kumar, Nirmal, Taily, Irshad Maajid, Singh, Charandeep, Kumar, Sahil, Rajmani, Raju S., Chakraborty, Debajyoti, Sharma, Anshul, Singh, Priyanka, Thakur, Krishan Gopal, Varadarajan, Raghavan, Ringe, Rajesh P., Banerjee, Prabal, Banerjee, Indranil
Publicado 2023

Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples

por Biji, Abhijith, Khatun, Oyahida, Swaraj, Shachee, Narayan, Rohan, Rajmani, Raju S., Sardar, Rahila, Satish, Deepshikha, Mehta, Simran, Bindhu, Hima, Jeevan, Madhumol, Saini, Deepak K., Singh, Amit, Gupta, Dinesh, Tripathi, Shashank
Publicado 2021

A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein

por Khatri, Bhavesh, Pramanick, Ishika, Malladi, Sameer Kumar, Rajmani, Raju S., Kumar, Sahil, Ghosh, Pritha, Sengupta, Nayanika, Rahisuddin, R., Kumar, Narender, Kumaran, S., Ringe, Rajesh P., Varadarajan, Raghavan, Dutta, Somnath, Chatterjee, Jayanta
Publicado 2022

Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe–4S cluster and regulates Fe–S cluster biogenesis for persistence in mice

por Anand, Kushi, Tripathi, Ashutosh, Shukla, Kaustubh, Malhotra, Nitish, Jamithireddy, Anil Kumar, Jha, Rajiv Kumar, Chaudhury, Susmit Narayan, Rajmani, Raju S., Ramesh, Arati, Nagaraja, Valakunja, Gopal, Balasubramanian, Nagaraju, Ganesh, Narain Seshayee, Aswin Sai, Singh, Amit
Publicado 2021

Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants

por Mittal, Nidhi, Kumar, Sahil, Rajmani, Raju S., Singh, Randhir, Lemoine, Céline, Jakob, Virginie, BJ, Sowrabha, Jagannath, Nayana, Bhat, Madhuraj, Chakraborty, Debajyoti, Pandey, Suman, Jory, Aurélie, SA, Suba Soundarya, Kleanthous, Harry, Dubois, Patrice, Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2023

Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis

por Shee, Somnath, Veetil, Reshma T, Mohanraj, Karthikeyan, Das, Mayashree, Malhotra, Nitish, Bandopadhyay, Devleena, Beig, Hussain, Birua, Shalini, Niphadkar, Shreyas, Nagarajan, Sathya Narayanan, Sinha, Vikrant Kumar, Thakur, Chandrani, Rajmani, Raju S, Chandra, Nagasuma, Laxman, Sunil, Singh, Mahavir, Samal, Areejit, Seshasayee, Aswin N, Singh, Amit
Publicado 2023

Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo

por Narayan, Rohan, Sharma, Mansi, Yadav, Rajesh, Biji, Abhijith, Khatun, Oyahida, Kaur, Sumandeep, Kanojia, Aditi, Joy, Christy Margrat, Rajmani, Raju, Sharma, Pallavi Raj, Jeyasankar, Sharumathi, Rani, Priya, Shandil, Radha Krishan, Narayanan, Shridhar, Rao, Durga Chilakalapudi, Satchidanandam, Vijaya, Das, Saumitra, Agarwal, Rachit, Tripathi, Shashank
Publicado 2023

A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern

por Ahmed, Shahbaz, Khan, Mohammad Suhail, Gayathri, Savitha, Singh, Randhir, Kumar, Sahil, Patel, Unnatiben Rajeshbhai, Malladi, Sameer Kumar, Rajmani, Raju S., van Vuren, Petrus Jansen, Riddell, Shane, Goldie, Sarah, Girish, Nidhi, Reddy, Poorvi, Upadhyaya, Aditya, Pandey, Suman, Siddiqui, Samreen, Tyagi, Akansha, Jha, Sujeet, Pandey, Rajesh, Khatun, Oyahida, Narayan, Rohan, Tripathi, Shashank, McAuley, Alexander J., Singanallur, Nagendrakumar Balasubramanian, Vasan, Seshadri S., Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2021

Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative

por Malladi, Sameer Kumar, Patel, Unnatiben Rajeshbhai, Rajmani, Raju S., Singh, Randhir, Pandey, Suman, Kumar, Sahil, Khaleeq, Sara, van Vuren, Petrus Jansen, Riddell, Shane, Goldie, Sarah, Gayathri, Savitha, Chakraborty, Debajyoti, Kalita, Parismita, Pramanick, Ishika, Agarwal, Nupur, Reddy, Poorvi, Girish, Nidhi, Upadhyaya, Aditya, Khan, Mohammad Suhail, Kanjo, Kawkab, Bhat, Madhuraj, Mani, Shailendra, Bhattacharyya, Sankar, Siddiqui, Samreen, Tyagi, Akansha, Jha, Sujeet, Pandey, Rajesh, Tripathi, Shashank, Dutta, Somnath, McAuley, Alexander J., Singanallur, Nagendrakumar Balasubramanian, Vasan, Seshadri S., Ringe, Rajesh P., Varadarajan, Raghavan
Publicado 2021