Guilt by Association: The Physical Chemistry and Biology of Protein Aggregation

por Raleigh, Daniel P.
Publicado 2014

The Ability of Insulin To Inhibit the Formation of Amyloid by Pro-Islet Amyloid Polypeptide Processing Intermediates Is Significantly Reduced in the Presence of Sulfated Glycosamin...

por Wang, Hui, Raleigh, Daniel P.
Publicado 2014

General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

por Wang, Hui, Raleigh, Daniel P.
Publicado 2014

Rationally Designed, Nontoxic, Nonamyloidogenic Analogues of Human Islet Amyloid Polypeptide with Improved Solubility

por Wang, Hui, Abedini, Andisheh, Ruzsicska, Bela, Raleigh, Daniel P.
Publicado 2014

A Structural Basis for the Regulation of an H-NOX-Associated Cyclic-di-GMP Synthase/Phosphodiesterase Enzyme by Nitric Oxide-Bound H-NOX

por Lahiri, Tanaya, Luan, Bowu, Raleigh, Daniel P., Boon, Elizabeth M.
Publicado 2014

Aspirin, Diabetes, and Amyloid: Re-examination of the Inhibition of Amyloid Formation by Aspirin and Ketoprofen

por Tu, Ling-Hsien, Noor, Harris, Cao, Ping, Raleigh, Daniel P.
Publicado 2014

On the plasticity of amyloid formation: The impact of destabilizing small to large substitutions on islet amyloid polypeptide amyloid formation

por Manathunga, Lakshan, Akter, Rehana, Zhyvoloup, Alexander, Simmerling, Carlos, Raleigh, Daniel P.
Publicado 2023

The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes w...

por Akter, Rehana, Zhyvoloup, Alexander, Zheng, Bingqian, Bhatia, Surita R., Raleigh, Daniel P.
Publicado 2019

Ion Mobility Spectrometry–Mass Spectrometry Defines the Oligomeric Intermediates in Amylin Amyloid Formation and the Mode of Action of Inhibitors

por Young, Lydia M., Cao, Ping, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.
Publicado 2013

Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions

por Peran, Ivan, Holehouse, Alex S., Carrico, Isaac S., Pappu, Rohit V., Bilsel, Osman, Raleigh, Daniel P.
Publicado 2019

Linking Gas-Phase and Solution-Phase Protein Unfolding via Mobile Proton Simulations

por Eldrid, Charles, Cragnolini, Tristan, Ben-Younis, Aisha, Zou, Junjie, Raleigh, Daniel P., Thalassinos, Konstantinos
Publicado 2022

Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

por Young, Lydia M., Tu, Ling-Hsien, Raleigh, Daniel P., Ashcroft, Alison E., Radford, Sheena E.
Publicado 2017

Histone H2B ubiquitylation disrupts local and higher order chromatin compaction

por Fierz, Beat, Chatterjee, Champak, McGinty, Robert K., Bar-Dagan, Maya, Raleigh, Daniel P., Muir, Tom W.
Publicado 2011

Tuning Protein Autoinhibition by Domain Destabilization

por Cho, Jae-Hyun, Muralidharan, Vasant, Vila-Perello, Miquel, Raleigh, Daniel P., Muir, Tom W., Palmer, Arthur G.
Publicado 2011

Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic–Inhibitor and Histidi...

por Tu, Ling-Hsien, Young, Lydia M., Wong, Amy G., Ashcroft, Alison E., Radford, Sheena E., Raleigh, Daniel P.
Publicado 2014

General Strategy for the Bioorthogonal Incorporation of Strongly Absorbing, Solvation-Sensitive Infrared Probes into Proteins

por Peran, Ivan, Oudenhoven, Tracey, Woys, Ann Marie, Watson, Matthew D., Zhang, Tianqi O., Carrico, Isaac, Zanni, Martin T., Raleigh, Daniel P.
Publicado 2014

Neprilysin Is Required for Angiotensin-(1–7)’s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1–2)

por Brar, Gurkirat S., Barrow, Breanne M., Watson, Matthew, Griesbach, Ryan, Choung, Edwina, Welch, Andrew, Ruzsicska, Bela, Raleigh, Daniel P., Zraika, Sakeneh
Publicado 2017

Defining the Molecular Basis of Amyloid Inhibitors: Human Islet Amyloid Polypeptide–Insulin Interactions

por Susa, Anna C., Wu, Chun, Bernstein, Summer L., Dupuis, Nicholas F., Wang, Hui, Raleigh, Daniel P., Shea, Joan-Emma, Bowers, Michael T.
Publicado 2014

Two-dimensional infrared spectroscopy reveals the complex behavior of an amyloid fibril inhibitor

por Middleton, Chris T., Marek, Peter, Cao, Ping, Chiu, Chi-cheng, Singh, Sadanand, Woys, Ann Marie, de Pablo, Juan J., Raleigh, Daniel P., Zanni, Martin T.
Publicado 2012

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

por Akter, Rehana, Cao, Ping, Noor, Harris, Ridgway, Zachary, Tu, Ling-Hsien, Wang, Hui, Wong, Amy G., Zhang, Xiaoxue, Abedini, Andisheh, Schmidt, Ann Marie, Raleigh, Daniel P.
Publicado 2016