Antitumorigenic effect of combination treatment with ONC201 and TRAIL in endometrial cancer in vitro and in vivo

por Ray, Jocelyn E., Ralff, Marie D., Jhaveri, Aakash, Zhou, Lanlan, Dicker, David T., Ross, Eric A., El-Deiry, Wafik S.
Publicado 2021

TRAIL receptor agonists convert the response of breast cancer cells to ONC201 from anti-proliferative to apoptotic

por Ralff, Marie D., Jhaveri, Aakash, Ray, Jocelyn E., Zhou, Lanlan, Lev, Avital, Campbell, Kerry S., Dicker, David T., Ross, Eric A., El-Deiry, Wafik S.
Publicado 2020

Role of Dopamine Receptors in the Anticancer Activity of ONC201()()

por Kline, Christina Leah B., Ralff, Marie D., Lulla, Amriti R., Wagner, Jessica M., Abbosh, Phillip H., Dicker, David T., Allen, Joshua E., El-Deiry, Wafik S.
Publicado 2017

Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo

por Jhaveri, Aakash V., Zhou, Lanlan, Ralff, Marie D., Lee, Young S., Navaraj, Arunasalam, Carneiro, Benedito A., Safran, Howard, Prabhu, Varun V., Ross, Eric A., Lee, Seulki, El-Deiry, Wafik S.
Publicado 2021

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

por Lev, Avital, Lulla, Amriti R., Wagner, Jessica, Ralff, Marie D., Kiehl, Joshua B., Zhou, Yan, Benes, Cyril H., Prabhu, Varun V., Oster, Wolfgang, Astsaturov, Igor, Dicker, David T., El-Deiry, Wafik S.
Publicado 2017

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors

por Prabhu, Varun V., Lulla, Amriti R., Madhukar, Neel S., Ralff, Marie D., Zhao, Dan, Kline, Christina Leah B., Van den Heuvel, A. Pieter J., Lev, Avital, Garnett, Mathew J., McDermott, Ultan, Benes, Cyril H., Batchelor, Tracy T., Chi, Andrew S., Elemento, Olivier, Allen, Joshua E., El-Deiry, Wafik S.
Publicado 2017

ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

por Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.
Publicado 2020