Reversibility of liver fibrosis

por Pellicoro, Antonella, Ramachandran, Prakash, Iredale, John P
Publicado 2012

Single-cell RNA-seq reveals CD16(-) monocytes as key regulators of human monocyte transcriptional response to Toxoplasma

por Patir, Anirudh, Gossner, Anton, Ramachandran, Prakash, Alves, Joana, Freeman, Tom C., Henderson, Neil C., Watson, Mick, Hassan, Musa A.
Publicado 2020

Macrophage derived Wnt signalling opposes Notch signalling in a Numb mediated manner to specify HPC fate in chronic liver disease in human and mouse

por Boulter, Luke, Govaere, Olivier, Bird, Tom G, Radulescu, Sorina, Ramachandran, Prakash, Pellicoro, Antonella, Ridgway, Rachel A, Seo, Sang Soo, Spee, Bart, Van Rooijen, Nico, Sansom, Owen J., Iredale, John P, Lowell, Sally, Roskams, Tania, Forbes, Stuart J
Publicado 2012

Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis

por King, Andrew, Houlihan, Diarmaid D., Kavanagh, Dean, Haldar, Debashis, Luu, Nguyet, Owen, Andrew, Suresh, Shankar, Than, Nwe Ni, Reynolds, Gary, Penny, Jasmine, Sumption, Henry, Ramachandran, Prakash, Henderson, Neil C., Kalia, Neena, Frampton, Jon, Adams, David H., Newsome, Philip N.
Publicado 2017

11Beta‐hydroxysteroid dehydrogenase‐1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis

por Zou, Xiantong, Ramachandran, Prakash, Kendall, Timothy J., Pellicoro, Antonella, Dora, Elena, Aucott, Rebecca L., Manwani, Kajal, Man, Tak Yung, Chapman, Karen E., Henderson, Neil C., Forbes, Stuart J., Webster, Scott P., Iredale, John P., Walker, Brian R., Michailidou, Zoi
Publicado 2018

An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease

por Kendall, Timothy J., Jimenez-Ramos, Maria, Turner, Frances, Ramachandran, Prakash, Minnier, Jessica, McColgan, Michael D., Alam, Masood, Ellis, Harriet, Dunbar, Donald R., Kohnen, Gabriele, Konanahalli, Prakash, Oien, Karin A., Bandiera, Lucia, Menolascina, Filippo, Juncker-Jensen, Anna, Alexander, Douglas, Mayor, Charlie, Guha, Indra Neil, Fallowfield, Jonathan A.
Publicado 2023

CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease

por Duan, Yi, Chu, Huikuan, Brandl, Katharina, Jiang, Lu, Zeng, Suling, Meshgin, Nairika, Papachristoforou, Eleni, Argemi, Josepmaria, Mendes, Beatriz G., Wang, Yanhan, Su, Hua, Sun, Weizhong, Llorente, Cristina, Hendrikx, Tim, Liu, Xiao, Hosseini, Mojgan, Kisseleva, Tatiana, Brenner, David A., Bataller, Ramon, Ramachandran, Prakash, Karin, Michael, Fu, Wenxian, Schnabl, Bernd
Publicado 2021

Macrophages promote anti-androgen resistance in prostate cancer bone disease

por Li, Xue-Feng, Selli, Cigdem, Zhou, Han-Lin, Cao, Jian, Wu, Shuiqing, Ma, Ruo-Yu, Lu, Ye, Zhang, Cheng-Bin, Xun, Bijie, Lam, Alyson D., Pang, Xiao-Cong, Fernando, Anu, Zhang, Zeda, Unciti-Broceta, Asier, Carragher, Neil O., Ramachandran, Prakash, Henderson, Neil C., Sun, Ling-Ling, Hu, Hai-Yan, Li, Gui-Bo, Sawyers, Charles, Qian, Bin-Zhi
Publicado 2023

Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

por Dobie, Ross, Wilson-Kanamori, John R., Henderson, Beth E.P., Smith, James R., Matchett, Kylie P., Portman, Jordan R., Wallenborg, Karolina, Picelli, Simone, Zagorska, Anna, Pendem, Swetha V., Hudson, Thomas E., Wu, Minnie M., Budas, Grant R., Breckenridge, David G., Harrison, Ewen M., Mole, Damian J., Wigmore, Stephen J., Ramachandran, Prakash, Ponting, Chris P., Teichmann, Sarah A., Marioni, John C., Henderson, Neil C.
Publicado 2019

Genome‐Wide Association Study of NAFLD Using Electronic Health Records

por Fairfield, Cameron J., Drake, Thomas M., Pius, Riinu, Bretherick, Andrew D., Campbell, Archie, Clark, David W., Fallowfield, Jonathan A., Hayward, Caroline, Henderson, Neil C., Joshi, Peter K., Mills, Nicholas L., Porteous, David J., Ramachandran, Prakash, Semple, Robert K., Shaw, Catherine A., Sudlow, Cathie L.M., Timmers, Paul R.H.J., Wilson, James F., Wigmore, Stephen J., Harrison, Ewen M., Spiliopoulou, Athina
Publicado 2021

Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial

por Snowdon, Victoria K., Lachlan, Neil J., Hoy, Anna M., Hadoke, Patrick W. F., Semple, Scott I., Patel, Dilip, Mungall, Will, Kendall, Timothy J., Thomson, Adrian, Lennen, Ross J., Jansen, Maurits A., Moran, Carmel M., Pellicoro, Antonella, Ramachandran, Prakash, Shaw, Isaac, Aucott, Rebecca L., Severin, Thomas, Saini, Rajnish, Pak, Judy, Yates, Denise, Dongre, Neelesh, Duffield, Jeremy S., Webb, David J., Iredale, John P., Hayes, Peter C., Fallowfield, Jonathan A.
Publicado 2017

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

por Kotsiliti, Elena, Leone, Valentina, Schuehle, Svenja, Govaere, Olivier, Li, Hai, Wolf, Monika J., Horvatic, Helena, Bierwirth, Sandra, Hundertmark, Jana, Inverso, Donato, Zizmare, Laimdota, Sarusi-Portuguez, Avital, Gupta, Revant, O’Connor, Tracy, Giannou, Anastasios D., Shiri, Ahmad Mustafa, Schlesinger, Yehuda, Beccaria, Maria Garcia, Rennert, Charlotte, Pfister, Dominik, Öllinger, Rupert, Gadjalova, Iana, Ramadori, Pierluigi, Rahbari, Mohammad, Rahbari, Nuh, Healy, Marc E., Fernández-Vaquero, Mirian, Yahoo, Neda, Janzen, Jakob, Singh, Indrabahadur, Fan, Chaofan, Liu, Xinyuan, Rau, Monika, Feuchtenberger, Martin, Schwaneck, Eva, Wallace, Sebastian J., Cockell, Simon, Wilson-Kanamori, John, Ramachandran, Prakash, Kho, Celia, Kendall, Timothy J., Leblond, Anne-Laure, Keppler, Selina J., Bielecki, Piotr, Steiger, Katja, Hofmann, Maike, Rippe, Karsten, Zitzelsberger, Horst, Weber, Achim, Malek, Nisar, Luedde, Tom, Vucur, Mihael, Augustin, Hellmut G., Flavell, Richard, Parnas, Oren, Rad, Roland, Pabst, Olivier, Henderson, Neil C., Huber, Samuel, Macpherson, Andrew, Knolle, Percy, Claassen, Manfred, Geier, Andreas, Trautwein, Christoph, Unger, Kristian, Elinav, Eran, Waisman, Ari, Abdullah, Zeinab, Haller, Dirk, Tacke, Frank, Anstee, Quentin M., Heikenwalder, Mathias
Publicado 2023