High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding

por Nguyen, Thuy-Tien T., Ramachandran, Sekar, Hill, Matthew J., Cerione, Richard A.
Publicado 2022

Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity

por Møller, Magda, Nielsen, Søren S., Ramachandran, Sekar, Li, Yuxing, Tria, Giancarlo, Streicher, Werner, Petoukhov, Maxim V., Cerione, Richard A., Gillilan, Richard E., Vestergaard, Bente
Publicado 2013

Correction: Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity

por Møller, Magda, Nielsen, Søren S., Ramachandran, Sekar, Yunxing, Li, Tria, Giancarlo, Streicher, Werner, Petoukhov, Maxim V., Cerione, Richard A., Gillilan, Richard E., Vestergaard, Bente
Publicado 2013

New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography

por Milano, Shawn K., Huang, Qingqiu, Nguyen, Thuy-Tien T., Ramachandran, Sekar, Finke, Aaron, Kriksunov, Irina, Schuller, David J., Szebenyi, D. Marian, Arenholz, Elke, McDermott, Lee A., Sukumar, N., Cerione, Richard A., Katt, William P.
Publicado 2021

Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

por Lukey, Michael J., Cluntun, Ahmad A., Katt, William P., Lin, Miao-chong J., Druso, Joseph E., Ramachandran, Sekar, Erickson, Jon W., Le, Henry H., Wang, Zhihan-Emily, Blank, Bryant, Greene, Kai Su, Cerione, Richard A.
Publicado 2019

Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures

por Bucki, Robert, Iwamoto, Daniel V., Shi, Xuechen, Kerr, Katherine E., Byfield, Fitzroy J., Suprewicz, Łukasz, Skłodowski, Karol, Sutaria, Julian, Misiak, Paweł, Wilczewska, Agnieszka Z., Ramachandran, Sekar, Wolfe, Aaron, Thanh, Minh-Tri Ho, Whalen, Eli, Patteson, Alison E., Janmey, Paul A.
Publicado 2023

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

por de Opakua, Alain Ibáñez, Parag-Sharma, Kshitij, DiGiacomo, Vincent, Merino, Nekane, Leyme, Anthony, Marivin, Arthur, Villate, Maider, Nguyen, Lien T., de la Cruz-Morcillo, Miguel Angel, Blanco-Canosa, Juan B., Ramachandran, Sekar, Baillie, George S., Cerione, Richard A., Blanco, Francisco J., Garcia-Marcos, Mikel
Publicado 2017