Pharmacodynamic Models of Differential Bortezomib Signaling Across Several Cell Lines of Multiple Myeloma

por Ramakrishnan, Vidya, Mager, Donald E.
Publicado 2018

gQSPSim: A SimBiology‐Based GUI for Standardized QSP Model Development and Application

por Hosseini, Iraj, Feigelman, Justin, Gajjala, Anita, Susilo, Monica, Ramakrishnan, Vidya, Ramanujan, Saroja, Gadkar, Kapil
Publicado 2020

Modeling Alzheimer's disease progression utilizing clinical trial and ADNI data to predict longitudinal trajectory of CDR‐SB

por Jamalian, Samira, Dolton, Michael, Chanu, Pascal, Ramakrishnan, Vidya, Franco, Yesenia, Wildsmith, Kristin, Manser, Paul, Teng, Edmond, Jin, Jin Y., Quartino, Angelica, Hsu, Joy C.
Publicado 2023

A phase I, randomized, ascending‐dose study to assess safety, pharmacokinetics, and activity of GDC‐8264, a RIP1 inhibitor, in healthy volunteers

por Jones, Nicholas S., Kshirsagar, Smita, Mohanan, Vishnu, Ramakrishnan, Vidya, Di Nucci, Flavia, Ma, Ling, Mao, Jialin, Ding, Hao, Klabunde, Sha, Vucic, Domagoj, Pan, Lin, Lekkerkerker, Annemarie N., Chen, Yuan, Rothenberg, Michael E.
Publicado 2023

Hallmarks of neurodegenerative disease: A systems pharmacology perspective

por Bloomingdale, Peter, Karelina, Tatiana, Ramakrishnan, Vidya, Bakshi, Suruchi, Véronneau‐Veilleux, Florence, Moye, Matthew, Sekiguchi, Kazutaka, Meno‐Tetang, Guy, Mohan, Aparna, Maithreye, R., Thomas, Veena A., Gibbons, Frank, Cabal, Antonio, Bouteiller, Jean‐Marie, Geerts, Hugo
Publicado 2022

Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: Lauriet

por Monteiro, Cecilia, Toth, Balazs, Brunstein, Flavia, Bobbala, Ashwini, Datta, Seema, Ceniceros, Ryan, Sanabria Bohorquez, Sandra M., Anania, Veronica G., Wildsmith, Kristin R., Schauer, Stephen P., Lee, Julie, Dolton, Michael J., Ramakrishnan, Vidya, Abramzon, Daniel, Teng, Edmond
Publicado 2023

Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial

por Teng, Edmond, Manser, Paul T., Pickthorn, Karen, Brunstein, Flavia, Blendstrup, Mira, Sanabria Bohorquez, Sandra, Wildsmith, Kristin R., Toth, Bali, Dolton, Michael, Ramakrishnan, Vidya, Bobbala, Ashwini, Sikkes, Sietske A. M., Ward, Michael, Fuji, Reina N., Kerchner, Geoffrey A.
Publicado 2022

Quantitative systems pharmacology model of the amyloid pathway in Alzheimer's disease: Insights into the therapeutic mechanisms of clinical candidates

por Ramakrishnan, Vidya, Friedrich, Christina, Witt, Colleen, Sheehan, Robert, Pryor, Meghan, Atwal, Jasvinder K., Wildsmith, Kristin, Kudrycki, Katherine, Lee, Seung‐Hye, Mazer, Norman, Hofmann, Carsten, Fuji, Reina N., Jin, Jin Y., Ramanujan, Saroja, Dolton, Michael, Quartino, Angelica
Publicado 2022