C1q, a small molecule with high impact on brain development: putative role for aging processes and the occurrence of Alzheimer’s disease

por Rupprecht, Christian, Rupprecht, Rainer, Rammes, Gerhard
Publicado 2021

DNA Damage, Neurodegeneration, and Synaptic Plasticity

por Merlo, Daniela, Cuchillo-Ibañez, Inmaculada, Parlato, Rosanna, Rammes, Gerhard
Publicado 2016

Quantification of astrocytic synaptic pruning in mouse hippocampal slices in response to ex vivo Aβ treatment via colocalization analysis with C1q

por Pradhan, Arpit Kumar, Shi, Qinfang, Tartler, Katharina Johanna, Rammes, Gerhard
Publicado 2022

The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease

por Russ, Hermann, Mazzanti, Michele, Parsons, Chris, Riemann, Katrin, Gebauer, Alexander, Rammes, Gerhard
Publicado 2022

Beta-Site Amyloid Precursor Protein-Cleaving Enzyme Inhibition Partly Restores Sevoflurane-Induced Deficits on Synaptic Plasticity and Spine Loss

por Wang, Xingxing, Shi, Qinfang, Pradhan, Arpit Kumar, Ziegon, Laura, Schlegel, Martin, Rammes, Gerhard
Publicado 2022

The Anaesthetics Isoflurane and Xenon Reverse the Synaptotoxic Effects of Aβ(1–42) on Megf10-Dependent Astrocytic Synapse Elimination and Spine Density in Ex Vivo Hippocampal Brain...

por Shi, Dai, Wong, Jaime K. Y., Zhu, Kaichuan, Noakes, Peter G., Rammes, Gerhard
Publicado 2023

Xenon’s Sedative Effect Is Mediated by Interaction with the Cyclic Nucleotide-Binding Domain (CNBD) of HCN2 Channels Expressed by Thalamocortical Neurons of the Ventrobasal Nucleus...

por Kassab, Nour El Dine, Mehlfeld, Verena, Kass, Jennifer, Biel, Martin, Schneider, Gerhard, Rammes, Gerhard
Publicado 2023

Identification of a Domain which Affects Kinetics and Antagonistic Potency of Clozapine at 5-HT(3) Receptors

por Rammes, Gerhard, Hosp, Christine, Eisensamer, Brigitte, Tanasic, Sascha, Nothdurfter, Caroline, Zieglgänsberger, Walter, Rupprecht, Rainer
Publicado 2009

Neurosteroids Mediate Neuroprotection in an In Vitro Model of Hypoxic/Hypoglycaemic Excitotoxicity via δ-GABA(A) Receptors without Affecting Synaptic Plasticity

por Puig-Bosch, Xènia, Ballmann, Markus, Bieletzki, Stefan, Antkowiak, Bernd, Rudolph, Uwe, Zeilhofer, Hanns Ulrich, Rammes, Gerhard
Publicado 2023

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation

por van Diggelen, Femke, Hrle, Dean, Apetri, Mihaela, Christiansen, Gunna, Rammes, Gerhard, Tepper, Armand, Otzen, Daniel Erik
Publicado 2019

Neurotoxicity of different amyloid beta subspecies in mice and their interaction with isoflurane anaesthesia

por Borgstedt, Laura, Blobner, Manfred, Musiol, Maximilian, Bratke, Sebastian, Syryca, Finn, Rammes, Gerhard, Jungwirth, Bettina, Schmid, Sebastian
Publicado 2020

Sevoflurane Anesthesia Improves Cognitive Performance in Mice, but Does Not Influence In Vitro Long-Term Potentation in Hippocampus CA1 Stratum Radiatum

por Haseneder, Rainer, Starker, Laura, Berkmann, Jasmin, Kellermann, Kristine, Jungwirth, Bettina, Blobner, Manfred, Eder, Matthias, Kochs, Eberhard, Rammes, Gerhard
Publicado 2013

Propofol and Sevoflurane Differentially Modulate Cortical Depolarization following Electric Stimulation of the Ventrobasal Thalamus

por Kratzer, Stephan, Mattusch, Corinna, Garcia, Paul S., Schmid, Sebastian, Kochs, Eberhard, Rammes, Gerhard, Schneider, Gerhard, Kreuzer, Matthias, Haseneder, Rainer
Publicado 2017

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels

por Kratzer, Stephan, Mattusch, Corinna, Metzger, Michael W., Dedic, Nina, Noll-Hussong, Michael, Kafitz, Karl W., Eder, Matthias, Deussing, Jan M., Holsboer, Florian, Kochs, Eberhard, Rammes, Gerhard
Publicado 2013

Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization

por Auffenberg, Eva, Jurik, Angela, Mattusch, Corinna, Stoffel, Rainer, Genewsky, Andreas, Namendorf, Christian, Schmid, Roland M., Rammes, Gerhard, Biel, Martin, Uhr, Manfred, Moosmang, Sven, Michalakis, Stylianos, Wotjak, Carsten T., Thoeringer, Christoph K.
Publicado 2016

Chronic administration of XBD173 ameliorates cognitive deficits and neuropathology via 18 kDa translocator protein (TSPO) in a mouse model of Alzheimer’s disease

por Pradhan, Arpit Kumar, Neumüller, Tatjana, Klug, Claudia, Fuchs, Severin, Schlegel, Martin, Ballmann, Markus, Tartler, Katharina Johanna, Pianos, Antoine, Garcia, Maria Sanchez, Liere, Philippe, Schumacher, Michael, Kreuzer, Matthias, Rupprecht, Rainer, Rammes, Gerhard
Publicado 2023

Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly

por Taş, Karin, Volta, Beatrice Dalla, Lindner, Christina, El Bounkari, Omar, Hille, Kathleen, Tian, Yuan, Puig-Bosch, Xènia, Ballmann, Markus, Hornung, Simon, Ortner, Martin, Prem, Sophia, Meier, Laura, Rammes, Gerhard, Haslbeck, Martin, Weber, Christian, Megens, Remco T. A., Bernhagen, Jürgen, Kapurniotu, Aphrodite
Publicado 2022

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3

por Pigoni, Martina, Hsia, Hung‐En, Hartmann, Jana, Rudan Njavro, Jasenka, Shmueli, Merav D, Müller, Stephan A, Güner, Gökhan, Tüshaus, Johanna, Kuhn, Peer‐Hendrik, Kumar, Rohit, Gao, Pan, Tran, Mai Ly, Ramazanov, Bulat, Blank, Birgit, Hipgrave Ederveen, Agnes L, Von Blume, Julia, Mulle, Christophe, Gunnersen, Jenny M, Wuhrer, Manfred, Rammes, Gerhard, Busche, Marc Aurel, Koeglsperger, Thomas, Lichtenthaler, Stefan F
Publicado 2020