Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

por Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Lakenberg, Nico, Suchiman, Eka, Mei, Hailiang, Kloppenburg, Margreet, Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Publicado 2021

The role of TNFRSF11B in development of osteoarthritic cartilage

por Rodríguez Ruiz, Alejandro, Tuerlings, Margo, Das, Ankita, Coutinho de Almeida, Rodrigo, Suchiman, H Eka D, Nelissen, Rob G H H, Ramos, Yolande F M, Meulenbelt, Ingrid
Publicado 2021

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

por Houtman, Evelyn, van Hoolwerff, Marcella, Lakenberg, Nico, Suchiman, Eka H. D., van der Linden-van der Zwaag, Enrike, Nelissen, Rob G. H. H., Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Characterizing the secretome of licensed hiPSC-derived MSCs

por Ramos, Yolande F. M., Tertel, Tobias, Shaw, Georgina, Staubach, Simon, de Almeida, Rodrigo Coutinho, Suchiman, Eka, Kuipers, Thomas B., Mei, Hailiang, Barry, Frank, Murphy, Mary, Giebel, Bernd, Meulenbelt, Ingrid
Publicado 2022

Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice

por Bomer, Nils, Cornelis, Frederique M. F., Ramos, Yolande F. M., den Hollander, Wouter, Lakenberg, Nico, van der Breggen, Ruud, Storms, Lies, Slagboom, P. Eline, Lories, Rik J. U., Meulenbelt, Ingrid
Publicado 2016

High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II

por van Hoolwerff, Marcella, Rodríguez Ruiz, Alejandro, Bouma, Marga, Suchiman, H. Eka D., Koning, Roman I., Jost, Carolina R., Mulder, Aat A., Freund, Christian, Guilak, Farshid, Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Genome-wide assessment of differential roles for p300 and CBP in transcription regulation

por Ramos, Yolande F. M., Hestand, Matthew S., Verlaan, Matty, Krabbendam, Elise, Ariyurek, Yavuz, van Galen, Michiel, van Dam, Hans, van Ommen, Gert-Jan B., den Dunnen, Johan T., Zantema, Alt, ′t Hoen, Peter A. C.
Publicado 2010

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

por Rodríguez Ruiz, Alejandro, Dicks, Amanda, Tuerlings, Margo, Schepers, Koen, van Pel, Melissa, Nelissen, Rob G. H. H., Freund, Christian, Mummery, Christine L., Orlova, Valeria, Guilak, Farshid, Meulenbelt, Ingrid, Ramos, Yolande F. M.
Publicado 2021

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

por Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D., van der Wal, Robert J. P., Nelissen, Rob G. H. H., Mei, Hailiang, Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage

por van Hoolwerff, Marcella, Metselaar, Paula I., Tuerlings, Margo, Suchiman, H. Eka D., Lakenberg, Nico, Ramos, Yolande F.M., Cats, Davy, Nelissen, Rob G.H.H., Broekhuis, Demiën, Mei, Hailiang, de Almeida, Rodrigo Coutinho, Meulenbelt, Ingrid
Publicado 2020

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

por Coutinho de Almeida, Rodrigo, Mahfouz, Ahmed, Mei, Hailiang, Houtman, Evelyn, den Hollander, Wouter, Soul, Jamie, Suchiman, Eka, Lakenberg, Nico, Meessen, Jennifer, Huetink, Kasper, Nelissen, Rob G H H, Ramos, Yolande F M, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2020

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis

por Tuerlings, Margo, van Hoolwerff, Marcella, van Bokkum, Jessica M, Suchiman, H Eka D, Lakenberg, Nico, Broekhuis, Demiën, Nelissen, Rob G H H, Ramos, Yolande F M, Mei, Hailiang, Cats, Davy, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study

por Ramos, Yolande F. M., den Hollander, Wouter, Bovée, Judith V. M. G., Bomer, Nils, van der Breggen, Ruud, Lakenberg, Nico, Keurentjes, J. Christiaan, Goeman, Jelle J., Slagboom, P. Eline, Nelissen, Rob G. H. H., Bos, Steffan D., Meulenbelt, Ingrid
Publicado 2014

Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization

por Rodríguez Ruiz, Alejandro, van Hoolwerff, Marcella, Sprangers, Sara, Suchiman, Eka, Schoenmaker, Ton, Dibbets-Schneider, Petra, Bloem, Johan L, Nelissen, Rob G H H, Freund, Christian, Mummery, Christine, Everts, Vincent, de Vries, Teun J, Ramos, Yolande F M, Meulenbelt, Ingrid
Publicado 2022

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes

por Houtman, Evelyn, Tuerlings, Margo, Suchiman, H Eka D, Lakenberg, Nico, Cornelis, Frederique M F, Mei, Hailiang, Broekhuis, Demiën, Nelissen, Rob G H H, Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Lories, Rik J, Cruz, Luis J, Meulenbelt, Ingrid
Publicado 2022

CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes

por Timmermans, Ritchie G.M., Blom, Arjen B., Bloks, Niek G.C., Nelissen, Rob. G.H.H., van der Linden, Enrike H.M.J., van der Kraan, Peter M., Meulenbelt, Ingrid, Ramos, Yolande F.M., van den Bosch, Martijn H.J.
Publicado 2022

Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis

por Peters, Marjolein J., Ramos, Yolande F.M., den Hollander, Wouter, Schiphof, Dieuwke, Hofman, Albert, Uitterlinden, André G., Oei, Edwin H.G., Slagboom, P. Eline, Kloppenburg, Margreet, Bloem, Johan L., Bierma-Zeinstra, Sita M.A., Meulenbelt, Ingrid, van Meurs, Joyce B.J.
Publicado 2016

Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants

por van Hoolwerff, Marcella, Tuerlings, Margo, Wijnen, Imke J L, Suchiman, H Eka D, Cats, Davy, Mei, Hailiang, Nelissen, Rob G H H, van der Linden–van der Zwaag, Henrike M J, Ramos, Yolande F M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2022

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

por Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Mahfouz, Ahmed, den Hollander, Wouter, Lakenberg, Nico, Houtman, Evelyn, van Hoolwerff, Marcella, Suchiman, H Eka D, Rodríguez Ruiz, Alejandro, Slagboom, P Eline, Mei, Hailiang, Kiełbasa, Szymon M, Nelissen, Rob G H H, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2019

A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress

por Timmermans, Ritchie G.M., Bloks, Niek G.C., Tuerlings, Margo, van Hoolwerff, Marcella, Nelissen, Rob G.H.H., van der Wal, Robert J.P., van der Kraan, Peter M., Blom, Arjen B., van den Bosch, Martijn H.J., Ramos, Yolande F.M., Meulenbelt, Ingrid
Publicado 2021