Soluble adenylyl cyclase is essential for proper lysosomal acidification

por Rahman, Nawreen, Ramos-Espiritu, Lavoisier, Milner, Teresa A., Buck, Jochen, Levin, Lonny R.
Publicado 2016

High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease

por Krumm, Christopher S., Landzberg, Renée S., Ramos-Espiritu, Lavoisier, Adura, Carolina, Liu, Xu, Acuna, Mariana, Xie, Yang, Xu, Xu, Tillman, Matthew C., Li, Yingxia, Glickman, J. Fraser, Ortlund, Eric A., Ginn, John D., Cohen, David E.
Publicado 2023

Human liver organoids for disease modeling of fibrolamellar carcinoma

por Narayan, Nicole J.C., Requena, David, Lalazar, Gadi, Ramos-Espiritu, Lavoisier, Ng, Denise, Levin, Solomon, Shebl, Bassem, Wang, Ruisi, Hammond, William J., Saltsman, James A., Gehart, Helmuth, Torbenson, Michael S., Clevers, Hans, LaQuaglia, Michael P., Simon, Sanford M.
Publicado 2022

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

por Ramos-Espiritu, Lavoisier, Diaz, Ana, Nardin, Charlee, Saviola, Anthony J., Shaw, Fiona, Plitt, Tamar, Yang, Xia, Wolchok, Jedd, Pirog, Edyta C., Desman, Garrett, Sboner, Andrea, Zhang, Tuo, Xiang, Jenny, Merghoub, Taha, Levin, Lonny R., Buck, Jochen, Zippin, Jonathan H.
Publicado 2016

Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase

por Ramos-Espiritu, Lavoisier, Kleinboelting, Silke, Navarrete, Felipe A., Alvau, Antonio, Visconti, Pablo E., Valsecchi, Federica, Starkov, Anatoly, Manfredi, Giovanni, Buck, Hannes, Adura, Carolina, Zippin, Jonathan H., van den Heuvel, Joop, Glickman, J. Fraser, Steegborn, Clemens, Levin, Lonny R., Buck, Jochen
Publicado 2016

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

por Lama, Lodoe, Adura, Carolina, Xie, Wei, Tomita, Daisuke, Kamei, Taku, Kuryavyi, Vitaly, Gogakos, Tasos, Steinberg, Joshua I., Miller, Michael, Ramos-Espiritu, Lavoisier, Asano, Yasutomi, Hashizume, Shogo, Aida, Jumpei, Imaeda, Toshihiro, Okamoto, Rei, Jennings, Andy J., Michino, Mayako, Kuroita, Takanobu, Stamford, Andrew, Gao, Pu, Meinke, Peter, Glickman, J. Fraser, Patel, Dinshaw J., Tuschl, Thomas
Publicado 2019