Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

por Latham, Tom, Mackay, Logan, Sproul, Duncan, Karim, Muhammed, Culley, Jayne, Harrison, David J, Hayward, Larry, Langridge-Smith, Pat, Gilbert, Nick, Ramsahoye, Bernard H
Publicado 2012

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

por Sproul, Duncan, Kitchen, Robert R, Nestor, Colm E, Dixon, J Michael, Sims, Andrew H, Harrison, David J, Ramsahoye, Bernard H, Meehan, Richard R
Publicado 2012

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain

por Lagger, Sabine, Connelly, John C., Schweikert, Gabriele, Webb, Shaun, Selfridge, Jim, Ramsahoye, Bernard H., Yu, Miao, He, Chuan, Sanguinetti, Guido, Sowers, Lawrence C., Walkinshaw, Malcolm D., Bird, Adrian
Publicado 2017

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

por Reddington, James P, Perricone, Sara M, Nestor, Colm E, Reichmann, Judith, Youngson, Neil A, Suzuki, Masako, Reinhardt, Diana, Dunican, Donncha S, Prendergast, James G, Mjoseng, Heidi, Ramsahoye, Bernard H, Whitelaw, Emma, Greally, John M, Adams, Ian R, Bickmore, Wendy A, Meehan, Richard R
Publicado 2013

ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy

por Handley, Mark T., Reddy, Kaalak, Wills, Jimi, Rosser, Elisabeth, Kamath, Archith, Halachev, Mihail, Falkous, Gavin, Williams, Denise, Cox, Phillip, Meynert, Alison, Raymond, Eleanor S., Morrison, Harris, Brown, Stephen, Allan, Emma, Aligianis, Irene, Jackson, Andrew P., Ramsahoye, Bernard H., von Kriegsheim, Alex, Taylor, Robert W., Finch, Andrew J., FitzPatrick, David R.
Publicado 2019

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis

por Redl, Elisa, Sheibani-Tezerji, Raheleh, Cardona, Crhistian de Jesus, Hamminger, Patricia, Timelthaler, Gerald, Hassler, Melanie Rosalia, Zrimšek, Maša, Lagger, Sabine, Dillinger, Thomas, Hofbauer, Lorena, Draganić, Kristina, Tiefenbacher, Andreas, Kothmayer, Michael, Dietz, Charles H, Ramsahoye, Bernard H, Kenner, Lukas, Bock, Christoph, Seiser, Christian, Ellmeier, Wilfried, Schweikert, Gabriele, Egger, Gerda
Publicado 2020