Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

por Harris, Rebecca, Randle, Suzanne, Laman, Heike
Publicado 2021

Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

por Nelson, David E., Randle, Suzanne J., Laman, Heike
Publicado 2013

Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression

por Randle, Suzanne J, Nelson, David E, Patel, Shachi P, Laman, Heike
Publicado 2015

Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27

por Patel, Shachi P., Randle, Suzanne J., Gibbs, Sarah, Cooke, Anne, Laman, Heike
Publicado 2016

Expression of Fbxo7 in Haematopoietic Progenitor Cells Cooperates with p53 Loss to Promote Lymphomagenesis

por Lomonosov, Mikhail, Meziane, El Kahina, Ye, Hongtao, Nelson, David E., Randle, Suzanne J., Laman, Heike
Publicado 2011

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

por Teixeira, Felipe Roberti, Randle, Suzanne J., Patel, Shachi P., Mevissen, Tycho E.T., Zenkeviciute, Grasilda, Koide, Tie, Komander, David, Laman, Heike
Publicado 2016

The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration

por St George-Hyslop, Peter, Lin, Julie Qiaojin, Miyashita, Akinori, Phillips, Emma C., Qamar, Seema, Randle, Suzanne J., Wang, GuoZhen
Publicado 2018

Loss of FBXO7 results in a Parkinson's‐like dopaminergic degeneration via an RPL23–MDM2–TP53 pathway

por Stott, Simon RW, Randle, Suzanne J, Al Rawi, Sara, Rowicka, Paulina A, Harris, Rebecca, Mason, Bethany, Xia, Jing, Dalley, Jeffrey W, Barker, Roger A, Laman, Heike
Publicado 2019

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling

por Rathje, Claudia C., Randle, Suzanne J., Al Rawi, Sara, Skinner, Benjamin M., Nelson, David E., Majumdar, Antara, Johnson, Emma E. P., Bacon, Joanne, Vlazaki, Myrto, Affara, Nabeel A., Ellis, Peter J., Laman, Heike
Publicado 2019

The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

por Spagnol, Valentine, Oliveira, Caio A.B., Randle, Suzanne J., Passos, Patrícia M.S., Correia, Camila R.S.T.B., Simaroli, Natália B., Oliveira, Joice S., Mevissen, Tycho E.T., Medeiros, Ana Carla, Gomes, Marcelo D., Komander, David, Laman, Heike, Teixeira, Felipe Roberti
Publicado 2021

The Parkinson’s disease genes Fbxo7 and Parkin interact to mediate mitophagy

por Burchell, Victoria S, Nelson, David E, Sanchez-Martinez, Alvaro, Delgado-Camprubi, Marta, Ivatt, Rachael M, Pogson, Joe H, Randle, Suzanne J, Wray, Selina, Lewis, Patrick A, Houlden, Henry, Abramov, Andrey Y, Hardy, John, Wood, Nicholas W, Whitworth, Alexander J, Laman, Heike, Plun-Favreau, Helene
Publicado 2013

Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors

por Chou, David B., Furlong, Brooke A., Posey, Ryan R., Kyprianou, Christos, O’Sullivan, Lucy R., David, Rhiannon, Randle, Suzanne J., Polanska, Urszula M., Travers, Jon, Urosevic, Jelena, Hutchinson, John N., Che, Jianwei, Howley, Anna M., Hasserjian, Robert P., Prantil-Baun, Rachelle, Ingber, Donald E.
Publicado 2022

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

por Qamar, Seema, Wang, GuoZhen, Randle, Suzanne J., Ruggeri, Francesco Simone, Varela, Juan A., Lin, Julie Qiaojin, Phillips, Emma C., Miyashita, Akinori, Williams, Declan, Ströhl, Florian, Meadows, William, Ferry, Rodylyn, Dardov, Victoria J., Tartaglia, Gian G., Farrer, Lindsay A., Kaminski Schierle, Gabriele S., Kaminski, Clemens F., Holt, Christine E., Fraser, Paul E., Schmitt-Ulms, Gerold, Klenerman, David, Knowles, Tuomas, Vendruscolo, Michele, St George-Hyslop, Peter
Publicado 2018