Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer

por Raninga, Prahlad V., Trapani, Giovanna Di, Tonissen, Kathryn F.
Publicado 2014

GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival

por Cabrera, Elisa, Raninga, Prahlad, Khanna, Kum Kum, Freire, Raimundo
Publicado 2019

Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

por Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Tonissen, Kathryn F.
Publicado 2016

CX-5461 Enhances the Efficacy of APR-246 via Induction of DNA Damage and Replication Stress in Triple-Negative Breast Cancer

por Makhale, Ashwini, Nanayakkara, Devathri, Raninga, Prahlad, Khanna, Kum Kum, Kalimutho, Murugan
Publicado 2021

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

por Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Bhatia, Maneet, Tonissen, Kathryn F.
Publicado 2015

Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment

por Clapper, Erin, Wang, Sicong, Raninga, Prahlad V., Di Trapani, Giovanna, Tonissen, Kathryn F.
Publicado 2020

Correction: Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

por Raninga, Prahlad V., Trapani, Giovanna Di, Vuckovic, Slavica, Bhatia, Maneet, Tonissen, Kathryn F.
Publicado 2021

A design of experiments screen reveals that Clostridium novyi-NT spore germinant sensing is stereoflexible for valine and its analogs

por Sundaresan, Ajitha, Le Ngoc, Mai, Wew, Marvell Ung, Ramkumar, Varsha, Raninga, Prahlad, Sum, Rongji, Cheong, Ian
Publicado 2023

Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8(+) T-cells infiltration in triple-negative breast cancer

por Kalimutho, Murugan, Sinha, Debottam, Mittal, Deepak, Srihari, Sriganesh, Nanayakkara, Devathri, Shafique, Shagufta, Raninga, Prahlad, Nag, Purba, Parsons, Kate, Khanna, Kum Kum
Publicado 2019

Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma

por Sze, Jun Hui, Raninga, Prahlad V., Nakamura, Kyohei, Casey, Mika, Khanna, Kum Kum, Berners-Price, Susan J., Di Trapani, Giovanna, Tonissen, Kathryn F.
Publicado 2019

CBL0137 impairs homologous recombination repair and sensitizes high-grade serous ovarian carcinoma to PARP inhibitors

por Lu, Xue, He, Yaowu, Johnston, Rebecca L., Nanayakarra, Devathri, Sankarasubramanian, Sivanandhini, Lopez, J. Alejandro, Friedlander, Michael, Kalimutho, Murugan, Hooper, John D., Raninga, Prahlad V., Khanna, Kum Kum
Publicado 2022

Cep55 overexpression promotes genomic instability and tumorigenesis in mice

por Sinha, Debottam, Nag, Purba, Nanayakkara, Devathri, Duijf, Pascal H. G., Burgess, Andrew, Raninga, Prahlad, Smits, Veronique A. J., Bain, Amanda L., Subramanian, Goutham, Wall, Meaghan, Finnie, John. W., Kalimutho, Murugan, Khanna, Kum Kum
Publicado 2020

Marizomib suppresses triple-negative breast cancer via proteasome and oxidative phosphorylation inhibition

por Raninga, Prahlad V., Lee, Andy, Sinha, Debottam, Dong, Lan-feng, Datta, Keshava K., Lu, Xue, Kalita-de Croft, Priyakshi, Dutt, Mriga, Hill, Michelle, Pouliot, Normand, Gowda, Harsha, Kalimutho, Murugan, Neuzil, Jiri, Khanna, Kum Kum
Publicado 2020

Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia

por Sinclair, Paul B., Cranston, Ruth E., Raninga, Prahlad, Cheng, Joanna, Hanna, Rebecca, Hawking, Zoe, Hair, Steven, Ryan, Sarra L., Enshaei, Amir, Nakjang, Sirintra, Rand, Vikki, Blair, Helen J., Moorman, Anthony V., Heidenreich, Olaf, Harrison, Christine J.
Publicado 2023

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

por Kalimutho, Murugan, Sinha, Debottam, Jeffery, Jessie, Nones, Katia, Srihari, Sriganesh, Fernando, Winnie C, Duijf, Pascal HG, Vennin, Claire, Raninga, Prahlad, Nanayakkara, Devathri, Mittal, Deepak, Saunus, Jodi M, Lakhani, Sunil R, López, J Alejandro, Spring, Kevin J, Timpson, Paul, Gabrielli, Brian, Waddell, Nicola, Khanna, Kum Kum
Publicado 2018

RNA-binding protein NONO contributes to cancer cell growth and confers drug resistance as a theranostic target in TNBC

por Kim, Seong-Jin, Ju, Jin-Sung, Kang, Myoung-Hee, Won, Ji Eun, Kim, Young Ha, Raninga, Prahlad V, Khanna, Kum Kum, Győrffy, Balázs, Pack, Chan-Gi, Han, Hee-Dong, Lee, Hee Jin, Gong, Gyungyub, Shin, Yong, Mills, Gordon B., Eyun, Seong-il, Park, Yun-Yong
Publicado 2020

Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer

por Poursani, Ensieh M., Mercatelli, Daniele, Raninga, Prahlad, Bell, Jessica L., Saletta, Federica, Kohane, Felix V., Neumann, Daniel P., Zheng, Ye, Rouaen, Jourdin R. C., Jue, Toni Rose, Michniewicz, Filip T., Schadel, Piper, Kasiou, Erin, Tsoli, Maria, Cirillo, Giuseppe, Waters, Shafagh, Shai-Hee, Tyler, Cazzoli, Riccardo, Brettle, Merryn, Slapetova, Iveta, Kasherman, Maria, Whan, Renee, Souza-Fonseca-Guimaraes, Fernando, Vahdat, Linda, Ziegler, David, Lock, John G., Giorgi, Federico M., Khanna, KumKum, Vittorio, Orazio
Publicado 2023