Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency

por Meuser, Megan E., Murphy, Michael B., Rashad, Adel A., Cocklin, Simon
Publicado 2018

Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor

por Meuser, Megan E., Rashad, Adel A., Ozorowski, Gabriel, Dick, Alexej, Ward, Andrew B., Cocklin, Simon
Publicado 2019

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry

por Ang, Charles Gotuaco, Carter, Erik, Haftl, Ann, Zhang, Shiyu, Rashad, Adel A., Kutzler, Michele, Abrams, Cameron F., Chaiken, Irwin M.
Publicado 2021

Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators

por Zhang, Shiyu, Holmes, Andrew P., Dick, Alexej, Rashad, Adel A., Enríquez Rodríguez, Lucía, Canziani, Gabriela A., Root, Michael J., Chaiken, Irwin M.
Publicado 2021

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2

por Kandeil, Ahmed, Mostafa, Ahmed, Kutkat, Omnia, Moatasim, Yassmin, Al-Karmalawy, Ahmed A., Rashad, Adel A., Kayed, Ahmed E., Kayed, Azza E., El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A.
Publicado 2021

FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2

por Mostafa, Ahmed, Kandeil, Ahmed, A. M. M. Elshaier, Yaseen, Kutkat, Omnia, Moatasim, Yassmin, Rashad, Adel A., Shehata, Mahmoud, Gomaa, Mokhtar R., Mahrous, Noura, Mahmoud, Sara H., GabAllah, Mohamed, Abbas, Hisham, Taweel, Ahmed El, Kayed, Ahmed E., Kamel, Mina Nabil, Sayes, Mohamed El, Mahmoud, Dina B., El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A.
Publicado 2020