Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library

por Mustonen, Enni-Kaisa, Pantsar, Tatu, Rashidian, Azam, Reiner, Juliander, Schwab, Matthias, Laufer, Stefan, Burk, Oliver
Publicado 2022

Discrepancy in interactions and conformational dynamics of pregnane X receptor (PXR) bound to an agonist and a novel competitive antagonist

por Rashidian, Azam, Mustonen, Enni-Kaisa, Kronenberger, Thales, Schwab, Matthias, Burk, Oliver, Laufer, Stefan A., Pantsar, Tatu
Publicado 2022

Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure

por Mejdrová, Ivana, Dušek, Jan, Škach, Kryštof, Stefela, Alžbeta, Skoda, Josef, Chalupský, Karel, Dohnalová, Klára, Pavkova, Ivona, Kronenberger, Thales, Rashidian, Azam, Smutná, Lucie, Duchoslav, Vojtěch, Smutny, Tomas, Pávek, Petr, Nencka, Radim
Publicado 2023