Lack of Allelic Exclusion in B Cell Chronic Lymphocytic Leukemia

por Rassenti, Laura Z., Kipps, Thomas J.
Publicado 1997

Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells

por Hasan, Md Kamrul, Rassenti, Laura, Widhopf, George F., Yu, Jian, Kipps, Thomas J.
Publicado 2018

Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism

por Hasan, Md Kamrul, Ghia, Emanuela M., Rassenti, Laura Z., Widhopf, George F., Kipps, Thomas J.
Publicado 2020

Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma

por Yu, Jian, Chen, Yun, Chen, Liguang, Zhang, Ling, Rassenti, Laura Z., Widhopf, George F., Kipps, Thomas J.
Publicado 2018

RITUXIMAB IN COMBINATION WITH HIGH DOSE METHYLPREDNISOLONE FOR THE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA

por Castro, Januario E., James, Danelle F., Sandoval-Sus, Jose D., Jain, Sonia, Bole, Janet, Rassenti, Laura, Kipps, Thomas J.
Publicado 2009

High expression level of ROR1 and ROR1-signaling associates with venetoclax resistance in chronic lymphocytic leukemia

por Ghia, Emanuela M., Rassenti, Laura Z., Choi, Michael Y., Quijada-Álamo, Miguel, Chu, Elvin, Widhopf, George F., Kipps, Thomas J.
Publicado 2022

B-cell Receptor Signaling Induced Metabolic Alterations in Chronic Lymphocytic Leukemia Can Be Partially Bypassed by TP53 Abnormalities

por Kluckova, Katarina, Clear, Andrew J., D’Avola, Annalisa, Rassenti, Laura Z., Kipps, Thomas J., Gribben, John G., Riches, John C.
Publicado 2022

A large fraction of trisomy 12, 17p(−), and 11q(−) CLL cases carry unidentified microdeletions of miR-15a/16-1

por Pepe, Felice, Rassenti, Laura Z., Pekarsky, Yuri, Labanowska, Jadwiga, Nakamura, Tatsuya, Nigita, Giovanni, Kipps, Thomas J., Balatti, Veronica, Croce, Carlo M.
Publicado 2022

Biased estimates of clonal evolution and subclonal heterogeneity can arise from PCR duplicates in deep sequencing experiments

por Smith, Erin N, Jepsen, Kristen, Khosroheidari, Mahdieh, Rassenti, Laura Z, D’Antonio, Matteo, Ghia, Emanuela M, Carson, Dennis A, Jamieson, Catriona HM, Kipps, Thomas J, Frazer, Kelly A
Publicado 2014

Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers

por DeBoever, Christopher, Ghia, Emanuela M., Shepard, Peter J., Rassenti, Laura, Barrett, Christian L., Jepsen, Kristen, Jamieson, Catriona H. M., Carson, Dennis, Kipps, Thomas J., Frazer, Kelly A.
Publicado 2015

The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience

por Van Dyke, Daniel L., Werner, Lillian, Rassenti, Laura Z., Neuberg, Donna, Ghia, Emanuella, Heerema, Nyla A., Dal Cin, Paola, Dell Aquila, Marie, Sreekantaiah, Chandrika, Greaves, Andrew W., Kipps, Thomas J., Kay, Neil E.
Publicado 2016

cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies

por Pedersen, Christina Bligaard, Dam, Søren Helweg, Barnkob, Mike Bogetofte, Leipold, Michael D., Purroy, Noelia, Rassenti, Laura Z., Kipps, Thomas J., Nguyen, Jennifer, Lederer, James Arthur, Gohil, Satyen Harish, Wu, Catherine J., Olsen, Lars Rønn
Publicado 2022

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

por Kämpjärvi, Kati, Järvinen, Tiina M., Heikkinen, Tuomas, Ruppert, Amy S., Senter, Leigha, Hoag, Kevin W., Dufva, Olli, Kontro, Mika, Rassenti, Laura, Hertlein, Erin, Kipps, Thomas J., Porkka, Kimmo, Byrd, John C., de la Chapelle, Albert, Vahteristo, Pia
Publicado 2014

HNRNPL Restrains miR-155 Targeting of BUB1 to Stabilize Aberrant Karyotypes of Transformed Cells in Chronic Lymphocytic Leukemia

por Pagotto, Sara, Veronese, Angelo, Soranno, Alessandra, Balatti, Veronica, Ramassone, Alice, Guanciali-Franchi, Paolo E., Palka, Giandomenico, Innocenti, Idanna, Autore, Francesco, Rassenti, Laura Z., Kipps, Thomas J., Mariani-Costantini, Renato, Laurenti, Luca, Croce, Carlo M., Visone, Rosa
Publicado 2019

Quaking and miR-155 interactions in inflammation and leukemogenesis

por Tili, Esmerina, Chiabai, Marcela, Palmieri, Dario, Brown, Melissa, Cui, Ri, Fernandes, Cecilia, Richmond, Tim, Kim, Taewan, Sheetz, Tyler, Sun, Hui-Lung, Lagana, Alessandro, Veneziano, Dario, Volinia, Stefano, Rassenti, Laura, Kipps, Thomas, Awad, Hamdy, Michaille, Jean-Jacques, Croce, Carlo M.
Publicado 2015

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathwa...

por Kashyap, Manoj K., Kumar, Deepak, Jones, Harrison, Amaya-Chanaga, Carlos I., Choi, Michael Y., Melo-Cardenas, Johanna, Ale-Ali, Amine, Kuhne, Michelle R., Sabbatini, Peter, Cohen, Lewis J., Shelat, Suresh G., Rassenti, Laura Z., Kipps, Thomas J., Cardarelli, Pina M., Castro, Januario E.
Publicado 2015

The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia

por Miller, Cecelia R., Ruppert, Amy S., Fobare, Sydney, Chen, Timothy L., Liu, Chaomei, Lehman, Amy, Blachly, James S., Zhang, Xiaoli, Lucas, David M., Grever, Michael R., Tallman, Martin S., Flinn, Ian W., Rassenti, Laura Z., Kipps, Thomas J., Sampath, Deepa, Coombes, Kevin R., Hertlein, Erin K.
Publicado 2017

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

por Rosenwald, Andreas, Alizadeh, Ash A., Widhopf, George, Simon, Richard, Davis, R. Eric, Yu, Xin, Yang, Liming, Pickeral, Oxana K., Rassenti, Laura Z., Powell, John, Botstein, David, Byrd, John C., Grever, Michael R., Cheson, Bruce D., Chiorazzi, Nicholas, Wilson, Wyndham H., Kipps, Thomas J., Brown, Patrick O., Staudt, Louis M.
Publicado 2001

Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia

por Kashyap, Manoj K., Amaya-Chanaga, Carlos I., Kumar, Deepak, Simmons, Brett, Huser, Nanni, Gu, Yin, Hallin, Max, Lindquist, Kevin, Yafawi, Rolla, Choi, Michael Y., Amine, Ale-Ali, Rassenti, Laura Z., Zhang, Cathy, Liu, Shu-Hui, Smeal, Tod, Fantin, Valeria R., Kipps, Thomas J., Pernasetti, Flavia, Castro, Januario E.
Publicado 2017

Characterization of a New Chronic Lymphocytic Leukemia Cell Line for Mechanistic In Vitro and In Vivo Studies Relevant to Disease

por Hertlein, Erin, Beckwith, Kyle A., Lozanski, Gerard, Chen, Timothy L., Towns, William H., Johnson, Amy J., Lehman, Amy, Ruppert, Amy S., Bolon, Brad, Andritsos, Leslie, Lozanski, Arletta, Rassenti, Laura, Zhao, Weiqiang, Jarvinen, Tiina M., Senter, Leigha, Croce, Carlo M., Symer, David E., de la Chapelle, Albert, Heerema, Nyla A., Byrd, John C.
Publicado 2013