Beyond Neuroprotection to Brain Repair: Exploring the Next Frontier in Clinical Neuroscience to Expand the Therapeutic Window for Stroke

por Ratan, Rajiv R.
Publicado 2010

Oxidative Stress and Huntington’s Disease: The Good, The Bad, and The Ugly

por Kumar, Amit, Ratan, Rajiv R.
Publicado 2016

Rehabilitation following hemorrhagic stroke: building the case for stroke-subtype specific recovery therapies

por Kitago, Tomoko, Ratan, Rajiv R.
Publicado 2017

Higher Blood Glucose within the Normal Range Is Associated with More Severe Strokes

por Martin, Rolf J., Ratan, Rajiv R., Reding, Michael J., Olsen, Tom S.
Publicado 2012

Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Müller Cell–Derived Inflammatory Cytokine Production in Diabetes

por Zhong, Yimin, Li, Jingming, Chen, Yanming, Wang, Joshua J., Ratan, Rajiv, Zhang, Sarah X.
Publicado 2012

Recent advances in hydrogen peroxide imaging for biological applications

por Guo, Hengchang, Aleyasin, Hossein, Dickinson, Bryan C, Haskew-Layton, Renée E, Ratan, Rajiv R
Publicado 2014

Suppression of Steady-state, but not Stimulus-induced NF-κB Activity Inhibits Alphavirus-induced Apoptosis

por Lin, Kuo-I, DiDonato, Joseph A., Hoffmann, Alexander, Marie Hardwick, J., Ratan, Rajiv R.
Publicado 1998

Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration

por Sleiman, Sama F., Berlin, Jill, Basso, Manuela, S.Karuppagounder, Saravanan, Rohr, Jürgen, Ratan, Rajiv R.
Publicado 2011

A STING agonist preconditions against ischaemic stroke via an adaptive antiviral Type 1 interferon response

por Kundu, Nandini, Kumar, Amit, Corona, Carlo, Chen, Yingxin, Seth, Sonia, Karuppagounder, Saravanan S., Ratan, Rajiv R.
Publicado 2022

The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson’s disease

por Aimé, Pascaline, Karuppagounder, Saravanan S., Rao, Apeksha, Chen, Yingxin, Burke, Robert E., Ratan, Rajiv R., Greene, Lloyd A.
Publicado 2020

Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors

por Zille, Marietta, Kumar, Amit, Kundu, Nandini, Bourassa, Megan W., Wong, Victor S. C., Willis, Dianna, Karuppagounder, Saravanan S., Ratan, Rajiv R.
Publicado 2019

ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

por Lange, Philipp S., Chavez, Juan C., Pinto, John T., Coppola, Giovanni, Sun, Chiao-Wang, Townes, Tim M., Geschwind, Daniel H., Ratan, Rajiv R.
Publicado 2008

Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats

por Ferguson, Adam R., Irvine, Karen-Amanda, Gensel, John C., Nielson, Jessica L., Lin, Amity, Ly, Johnathan, Segal, Mark R., Ratan, Rajiv R., Bresnahan, Jacqueline C., Beattie, Michael S.
Publicado 2013

Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery

por Wei, George Z., Saraswat Ohri, Sujata, Khattar, Nicolas K., Listerman, Adam W., Doyle, Catherine H., Andres, Kariena R., Karuppagounder, Saravanan S., Ratan, Rajiv R., Whittemore, Scott R., Hetman, Michal
Publicado 2021

Paired Associative Stimulation as a Tool to Assess Plasticity Enhancers in Chronic Stroke

por Silverstein, Joshua, Cortes, Mar, Tsagaris, Katherine Zoe, Climent, Alejandra, Gerber, Linda M., Oromendia, Clara, Fonzetti, Pasquale, Ratan, Rajiv R., Kitago, Tomoko, Iacoboni, Marco, Wu, Allan, Dobkin, Bruce, Edwards, Dylan J.
Publicado 2019

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

por Sleiman, Sama F, Henry, Jeffrey, Al-Haddad, Rami, El Hayek, Lauretta, Abou Haidar, Edwina, Stringer, Thomas, Ulja, Devyani, Karuppagounder, Saravanan S, Holson, Edward B, Ratan, Rajiv R, Ninan, Ipe, Chao, Moses V
Publicado 2016

HIF1α stabilization in hypoxia is not oxidant-initiated

por Kumar, Amit, Vaish, Manisha, Karuppagounder, Saravanan S, Gazaryan, Irina, Cave, John W, Starkov, Anatoly A, Anderson, Elizabeth T, Zhang, Sheng, Pinto, John T, Rountree, Austin M, Wang, Wang, Sweet, Ian R, Ratan, Rajiv R
Publicado 2021

Harnessing hypoxic adaptation to prevent, treat, and repair stroke

por Ratan, Rajiv R., Siddiq, Ambreena, Smirnova, Natalya, Karpisheva, Ksenia, Haskew-Layton, Renee, McConoughey, Stephen, Langley, Brett, Estevez, Alvaro, Huerta, Patricio T., Volpe, Bruce, Roy, Sashwati, Sen, Chandan K., Gazaryan, Irina, Cho, Sunghee, Fink, Matthew, LaManna, Joseph
Publicado 2007

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington’s Disease Knock-In Mouse Models

por Franich, Nicholas R., Basso, Manuela, André, Emily A., Ochaba, Joseph, Kumar, Amit, Thein, Soe, Fote, Gianna, Kachemov, Marketta, Lau, Alice L., Yeung, Sylvia Y., Osmand, Alexander, Zeitlin, Scott O., Ratan, Rajiv R., Thompson, Leslie M., Steffan, Joan S.
Publicado 2018

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease

por Smirnova, Natalya A., Kaidery, Navneet Ammal, Hushpulian, Dmitry M., Rakhman, Ilay I., Poloznikov, Andrey A., Tishkov, Vladimir I., Karuppagounder, Saravanan S., Gaisina, Irina N., Pekcec, Anton, Leyen, Klaus Van, Kazakov, Sergey V., Yang, Lichuan, Thomas, Bobby, Ratan, Rajiv R., Gazaryan, Irina G.
Publicado 2016