HGF-induced migration depends on the PI(3,4,5)P(3)-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1

por Ratcliffe, Colin D.H., Siddiqui, Nadeem, Coelho, Paula P., Laterreur, Nancy, Cookey, Tumini N., Sonenberg, Nahum, Park, Morag
Publicado 2019

Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms

por Kondo, Hiroshi, Ratcliffe, Colin D.H., Hooper, Steven, Ellis, James, MacRae, James I., Hennequart, Marc, Dunsby, Christopher W., Anderson, Kurt I., Sahai, Erik
Publicado 2021

EphB6 Regulates TFEB-Lysosomal Pathway and Survival of Disseminated Indolent Breast Cancer Cells

por Zangrossi, Manuela, Romani, Patrizia, Chakravarty, Probir, Ratcliffe, Colin D.H., Hooper, Steven, Dori, Martina, Forcato, Mattia, Bicciato, Silvio, Dupont, Sirio, Sahai, Erik, Montagner, Marco
Publicado 2021

Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation

por Coelho, Paula P., Hesketh, Geoffrey G., Pedersen, Annika, Kuzmin, Elena, Fortier, Anne-Marie N., Bell, Emily S., Ratcliffe, Colin D. H., Gingras, Anne-Claude, Park, Morag
Publicado 2022

Cross-talk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination

por Montagner, Marco, Bhome, Rahul, Hooper, Steven, Chakravarty, Probir, Qin, Xiao, Sufi, Jahangir, Bhargava, Ajay, Ratcliffe, Colin D. H., Naito, Yutaka, Pocaterra, Arianna, Tape, Chris, Sahai, Erik
Publicado 2020

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family

por Trempe, Jean-François, Šašková, Klára Grantz, Sivá, Monika, Ratcliffe, Colin D. H., Veverka, Václav, Hoegl, Annabelle, Ménade, Marie, Feng, Xin, Shenker, Solomon, Svoboda, Michal, Kožíšek, Milan, Konvalinka, Jan, Gehring, Kalle
Publicado 2016

5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion

por Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Gertler, Frank B., Siegel, Peter M., Park, Morag
Publicado 2016

BSCI-11. Targeting PI3K/Akt/mTOR pathway to prevent melanoma brain metastasis

por Tehranian, Cedric, Fankhauser, Laura, Harter, Patrick N, Ratcliffe, Colin D H, Zeiner, Pia S, Messmer, Julia M, Hoffmann, Dirk C, Frey, Katharina, Westphal, Dana, Ronellenfitsch, Michael W, Sahai, Erik, Wick, Wolfgang, Karreman, Matthia A, Winkler, Frank
Publicado 2021

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer

por Knight, Jennifer F., Sung, Vanessa Y.C., Kuzmin, Elena, Couzens, Amber L., de Verteuil, Danielle A., Ratcliffe, Colin D.H., Coelho, Paula P., Johnson, Radia M., Samavarchi-Tehrani, Payman, Gruosso, Tina, Smith, Harvey W., Lee, Wontae, Saleh, Sadiq M., Zuo, Dongmei, Zhao, Hong, Guiot, Marie-Christine, Davis, Ryan R., Gregg, Jeffrey P., Moraes, Christopher, Gingras, Anne-Claude, Park, Morag
Publicado 2018