Oncogenic switching of hypoxia signalling pathways

por Ratcliffe, Peter J
Publicado 2014

Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways

por Masson, Norma, Ratcliffe, Peter J
Publicado 2014

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives

por Bishop, Tammie, Ratcliffe, Peter J
Publicado 2014

Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer

por Sugimoto, Yoichiro, Ratcliffe, Peter J.
Publicado 2022

New horizons in hypoxia signaling pathways

por Pugh, Christopher W., Ratcliffe, Peter J.
Publicado 2017

Novel Insights into FH-associated Disease are KEAPing the Lid on Oncogenic HIF Signalling

por Adam, Julie, Ratcliffe, Peter J., Pollard, Patrick J.
Publicado 2011

The human side of hypoxia-inducible factor

por Smith, Thomas G, Robbins, Peter A, Ratcliffe, Peter J
Publicado 2008

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

por Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Publicado 2016

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively

por Wang, Yihua, Zhong, Shan, Schofield, Christopher J., Ratcliffe, Peter J., Lu, Xin
Publicado 2018

Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells

por Tian, Ya-Min, Holdship, Philip, To, Trang Quynh, Ratcliffe, Peter J., Keeley, Thomas P.
Publicado 2023

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma

por Lafleur, Véronique N, Halim, Silvia, Choudhry, Hani, Ratcliffe, Peter J, Mole, David R
Publicado 2023

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

por Lombardi, Olivia, Li, Ran, Halim, Silvia, Choudhry, Hani, Ratcliffe, Peter J., Mole, David R.
Publicado 2022

Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-contain...

por Cockman, Matthew E., Webb, James D., Kramer, Holger B., Kessler, Benedikt M., Ratcliffe, Peter J.
Publicado 2009

Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation

por Singleton, Rachelle S., Trudgian, David C., Fischer, Roman, Kessler, Benedikt M., Ratcliffe, Peter J., Cockman, Matthew E.
Publicado 2011

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

por Mole, David R., Blancher, Christine, Copley, Richard R., Pollard, Patrick J., Gleadle, Jonathan M., Ragoussis, Jiannis, Ratcliffe, Peter J.
Publicado 2009

A global view of the aspiring physician-scientist

por Williams, Christopher S, Rathmell, W Kimryn, Carethers, John M, Harper, Diane M, Lo, YM Dennis, Ratcliffe, Peter J, Zaidi, Mone
Publicado 2022

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

por Choudhry, Hani, Schödel, Johannes, Oikonomopoulos, Spyros, Camps, Carme, Grampp, Steffen, Harris, Adrian L, Ratcliffe, Peter J, Ragoussis, Jiannis, Mole, David R
Publicado 2014

Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

por Platt, James L, Salama, Rafik, Smythies, James, Choudhry, Hani, Davies, James OJ, Hughes, Jim R, Ratcliffe, Peter J, Mole, David R
Publicado 2016

The increase in pulmonary arterial pressure caused by hypoxia depends on iron status

por Smith, Thomas G, Balanos, George M, Croft, Quentin P P, Talbot, Nick P, Dorrington, Keith L, Ratcliffe, Peter J, Robbins, Peter A
Publicado 2008

Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells

por Simpson, Peter D., Eipper, Betty A., Katz, Maximiliano J., Gandara, Lautaro, Wappner, Pablo, Fischer, Roman, Hodson, Emma J., Ratcliffe, Peter J., Masson, Norma
Publicado 2015