Identifying small molecule probes of ENTPD5 through high throughput screening

por Durst, Matthew A., Ratia, Kiira, Lavie, Arnon
Publicado 2019

Coronavirus Papain-like Peptidases

por Ratia, Kiira, Mesecar, Andrew, O’Brien, Amornrat, Baker, Susan C.
Publicado 2013

Inhibition of Aβ(42) oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs

por Park, Sei-Kyoung, Ratia, Kiira, Ba, Mariam, Valencik, Maria, Liebman, Susan W.
Publicado 2016

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

por Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Publicado 2014

Evaluating the 3C-like protease activity of SARS-Coronavirus: Recommendations for standardized assays for drug discovery

por Grum-Tokars, Valerie, Ratia, Kiira, Begaye, Adrian, Baker, Susan C., Mesecar, Andrew D.
Publicado 2008

Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase

por Ratia, Kiira, Light, Samuel H., Antanasijevic, Aleksandar, Anderson, Wayne F., Caffrey, Michael, Lavie, Arnon
Publicado 2014

Deubiquitinating Activity of the SARS-CoV Papain-Like Protease

por Barretto, Naina, Jukneliene, Dalia, Ratia, Kiira, Chen, Zhongbin, Mesecar, Andrew D., Baker, Susan C.
Publicado 2006

Identification of Quorum-Sensing Inhibitors Disrupting Signaling between Rgg and Short Hydrophobic Peptides in Streptococci

por Aggarwal, Chaitanya, Jimenez, Juan Cristobal, Lee, Hyun, Chlipala, George E., Ratia, Kiira, Federle, Michael J.
Publicado 2015

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

por Ghosh, Arun K., Xi, Kai, Grum-Tokars, Valerie, Xu, Xiaoming, Ratia, Kiira, Fu, Wentao, Houser, Katherine V., Baker, Susan C., Johnson, Michael E., Mesecar, Andrew D.
Publicado 2007

XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer

por Principe, Daniel R., Xiong, Rui, Li, Yangfeng, Pham, Thao N. D., Kamath, Suneel D., Dubrovskyi, Oleksii, Ratia, Kiira, Huang, Fei, Zhao, Jiong, Shen, Zhengnan, Thummuri, Dinesh, Daohong, Zhou, Underwood, Patrick W., Trevino, Jose, Munshi, Hidayatullah G., Thatcher, Gregory R. J., Rana, Ajay
Publicado 2022

PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer

por Salvi, Amrita, Young, Alexandria N., Huntsman, Andrew C., Pergande, Melissa R., Korkmaz, Melissa A., Rathnayake, Rathnayake A., Mize, Brittney K., Kinghorn, A. Douglas, Zhang, Xiaoli, Ratia, Kiira, Schirle, Markus, Thomas, Jason R., Brittain, Scott M., Shelton, Claude, Aldrich, Leslie N., Cologna, Stephanie M., Fuchs, James R., Burdette, Joanna E.
Publicado 2022