Trade-off between Responsiveness and Noise Suppression in Biomolecular System Responses to Environmental Cues

por Ratushny, Alexander V., Shmulevich, Ilya, Aitchison, John D.
Publicado 2011

Systems cell biology

por Mast, Fred D., Ratushny, Alexander V., Aitchison, John D.
Publicado 2014

Patient-Specific Cell Communication Networks Associate With Disease Progression in Cancer

por Gibbs, David L., Aguilar, Boris, Thorsson, Vésteinn, Ratushny, Alexander V., Shmulevich, Ilya
Publicado 2021

Asymmetric positive feedback loops reliably control biological responses

por Ratushny, Alexander V, Saleem, Ramsey A, Sitko, Katherine, Ramsey, Stephen A, Aitchison, John D
Publicado 2012

Analysis of cellular kinetic models suggest that physiologically based model parameters may be inherently, practically unidentifiable

por Brown, Liam V., Coles, Mark C., McConnell, Mark, Ratushny, Alexander V., Gaffney, Eamonn A.
Publicado 2022

One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!

por Herricks, Thurston, Dilworth, David J., Mast, Fred D., Li, Song, Smith, Jennifer J., Ratushny, Alexander V., Aitchison, John D.
Publicado 2016

Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions

por Danziger, Samuel A, Reiss, David J, Ratushny, Alexander V, Smith, Jennifer J, Plaisier, Christopher L, Aitchison, John D, Baliga, Nitin S
Publicado 2015

ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells

por Danziger, Samuel A., Gibbs, David L., Shmulevich, Ilya, McConnell, Mark, Trotter, Matthew W. B., Schmitz, Frank, Reiss, David J., Ratushny, Alexander V.
Publicado 2019

A FOXO3/IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

por Litvak, Vladimir, Ratushny, Alexander V., Lampano, Aaron E., Schmitz, Frank, Huang, Albert C., Raman, Ayush, Rust, Alistair G., Bergthaler, Andreas, Aitchison, John D., Aderem, Alan
Publicado 2012

Metallochaperones Regulate Intracellular Copper Levels

por Pang, W. Lee, Kaur, Amardeep, Ratushny, Alexander V., Cvetkovic, Aleksandar, Kumar, Sunil, Pan, Min, Arkin, Adam P., Aitchison, John D., Adams, Michael W. W., Baliga, Nitin S.
Publicado 2013

A generalizable data-driven multicellular model of pancreatic ductal adenocarcinoma

por Aguilar, Boris, Gibbs, David L, Reiss, David J, McConnell, Mark, Danziger, Samuel A, Dervan, Andrew, Trotter, Matthew, Bassett, Douglas, Hershberg, Robert, Ratushny, Alexander V, Shmulevich, Ilya
Publicado 2020

Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies

por Abbiati, Roberto A., Pourdehnad, Michael, Carrancio, Soraya, Pierce, Daniel W., Kasibhatla, Shailaja, McConnell, Mark, Trotter, Matthew W. B., Loos, Remco, Santini, Cristina C., Ratushny, Alexander V.
Publicado 2021

Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity

por Holden, Jennifer M., Koreny, Ludek, Obado, Samson, Ratushny, Alexander V., Chen, Wei-Ming, Chiang, Jung-Hsien, Kelly, Steven, Chait, Brian T., Aitchison, John D., Rout, Michael P., Field, Mark C.
Publicado 2014

Involvement in surface antigen expression by a moonlighting FG-repeat nucleoporin in trypanosomes

por Holden, Jennifer M., Koreny, Ludek, Obado, Samson, Ratushny, Alexander V., Chen, Wei-Ming, Bart, Jean-Mathieu, Navarro, Miguel, Chait, Brian T., Aitchison, John D., Rout, Michael P., Field, Mark C.
Publicado 2018

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression

por Maishman, Luke, Obado, Samson O., Alsford, Sam, Bart, Jean-Mathieu, Chen, Wei-Ming, Ratushny, Alexander V., Navarro, Miguel, Horn, David, Aitchison, John D., Chait, Brian T., Rout, Michael P., Field, Mark C.
Publicado 2016

Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer’s Disease Brain

por Korvatska, Olena, Kiianitsa, Kostantin, Ratushny, Alexander, Matsushita, Mark, Beeman, Neal, Chien, Wei-Ming, Satoh, Jun-Ichi, Dorschner, Michael O., Keene, C. Dirk, Bammler, Theo K., Bird, Thomas D., Raskind, Wendy H.
Publicado 2020

Molecular mechanisms of system responses to novel stimuli are predictable from public data

por Danziger, Samuel A., Ratushny, Alexander V., Smith, Jennifer J., Saleem, Ramsey A., Wan, Yakun, Arens, Christina E., Armstrong, Abraham M., Sitko, Katherine, Chen, Wei-Ming, Chiang, Jung-Hsien, Reiss, David J., Baliga, Nitin S., Aitchison, John D.
Publicado 2014

Integrative network modeling reveals mechanisms underlying T cell exhaustion

por Bolouri, Hamid, Young, Mary, Beilke, Joshua, Johnson, Rebecca, Fox, Brian, Huang, Lu, Santini, Cristina Costa, Hill, Christopher Mark, Vries, Anne-Renee van der Vuurst de, Shannon, Paul T., Dervan, Andrew, Sivakumar, Pallavur, Trotter, Matthew, Bassett, Douglas, Ratushny, Alexander
Publicado 2020

NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

por DuBois, Kelly N., Alsford, Sam, Holden, Jennifer M., Buisson, Johanna, Swiderski, Michal, Bart, Jean-Mathieu, Ratushny, Alexander V., Wan, Yakun, Bastin, Philippe, Barry, J. David, Navarro, Miguel, Horn, David, Aitchison, John D., Rout, Michael P., Field, Mark C.
Publicado 2012

Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma

por Wall, Matthew A., Turkarslan, Serdar, Wu, Wei-Ju, Danziger, Samuel A., Reiss, David J., Mason, Mike J., Dervan, Andrew P., Trotter, Matthew W. B., Bassett, Douglas, Hershberg, Robert M., Lomana, Adrián López García de, Ratushny, Alexander V., Baliga, Nitin S.
Publicado 2021