Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells

por Srisongkram, Tarapong, Weerapreeyakul, Natthida, Kärkkäinen, Jussi, Rautio, Jarkko
Publicado 2019

Intranasal Nanoemulsions for Direct Nose-to-Brain Delivery of Actives for CNS Disorders

por Bahadur, Shiv, Pardhi, Dinesh M., Rautio, Jarkko, Rosenholm, Jessica M., Pathak, Kamla
Publicado 2020

Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma

por Srisongkram, Tarapong, Bahrami, Katayun, Järvinen, Juulia, Timonen, Juri, Rautio, Jarkko, Weerapreeyakul, Natthida
Publicado 2022

Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7

por Pocasap, Piman, Weerapreeyakul, Natthida, Timonen, Juri, Järvinen, Juulia, Leppänen, Jukka, Kärkkäinen, Jussi, Rautio, Jarkko
Publicado 2020

Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates

por Bahrami, Katayun, Järvinen, Juulia, Laitinen, Tuomo, Reinisalo, Mika, Honkakoski, Paavo, Poso, Antti, Huttunen, Kristiina M., Rautio, Jarkko
Publicado 2022

Sweet Battle of the Epimers—Continued Exploration of Monosaccharide-Derived Delivery Agents for Boron Neutron Capture Therapy

por Matović, Jelena, Bahrami, Katayun, Stockmann, Philipp, Sokka, Iris K., Khng, You Cheng, Sarparanta, Mirkka, Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.
Publicado 2023

Synthesis and In Vitro Evaluation of a Set of 6-Deoxy-6-thio-carboranyl d-Glucoconjugates Shed Light on the Substrate Specificity of the GLUT1 Transporter

por Matović, Jelena, Järvinen, Juulia, Sokka, Iris K., Stockmann, Philipp, Kellert, Martin, Imlimthan, Surachet, Sarparanta, Mirkka, Johansson, Mikael P., Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.
Publicado 2022

Development of Lyophilised Eudragit(®) Retard Nanoparticles for the Sustained Release of Clozapine via Intranasal Administration

por Lombardo, Rosamaria, Ruponen, Marika, Rautio, Jarkko, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Calosi, Laura, Bani, Daniele, Lampinen, Riikka, Kanninen, Katja M., Koivisto, Anne M., Penttilä, Elina, Löppönen, Heikki, Pignatello, Rosario
Publicado 2023

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes

por Muñoz-Torrero, Diego, Mangoni, Arduino A., Guillou, Catherine, Collina, Simona, Vanden Eynde, Jean Jacques, Rautio, Jarkko, Keserű, György M., Hulme, Christopher, Chibale, Kelly, Luque, F. Javier, Karaman, Rafik, Gütschow, Michael, Liu, Hong, Ragno, Rino
Publicado 2017

Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing l-Thyroxine-Derived Prodrugs

por Tonduru, Arun Kumar, Maljaei, Seyed Hamed, Adla, Santosh Kumar, Anamea, Landry, Tampio, Janne, Králová, Adéla, Jalkanen, Aaro J., Espada, Catarina, Santos, Inês Falcato, Montaser, Ahmed B., Rautio, Jarkko, Kronenberger, Thales, Poso, Antti, Huttunen, Kristiina M.
Publicado 2023

Addressing the Biochemical Foundations of a Glucose-Based “Trojan Horse”-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment

por Matović, Jelena, Järvinen, Juulia, Bland, Helena C., Sokka, Iris K., Imlimthan, Surachet, Ferrando, Ruth Mateu, Huttunen, Kristiina M., Timonen, Juri, Peräniemi, Sirpa, Aitio, Olli, Airaksinen, Anu J., Sarparanta, Mirkka, Johansson, Mikael P., Rautio, Jarkko, Ekholm, Filip S.
Publicado 2020

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2

por Muñoz-Torrero, Diego, Mangoni, Arduino A., Liu, Hong, Hulme, Christopher, Rautio, Jarkko, Karaman, Rafik, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Sabatier, Jean-Marc, Siciliano, Carlo, Luque, F. Javier, Kokotos, George, Ragno, Rino, Collina, Simona, Guillou, Catherine, Gütschow, Michael, Agrofoglio, Luigi A.
Publicado 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

por Mangoni, Arduino A., Tuccinardi, Tiziano, Collina, Simona, Vanden Eynde, Jean Jacques, Muñoz-Torrero, Diego, Karaman, Rafik, Siciliano, Carlo, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Rautio, Jarkko, Guillou, Catherine, Gütschow, Michael, Galdiero, Stefania, Liu, Hong, Agrofoglio, Luigi A., Sabatier, Jean-Marc, Hulme, Christopher, Kokotos, George, You, Qidong, Gomes, Paula A. C.
Publicado 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4

por Mangoni, Arduino A, Guillou, Catherine, Vanden Eynde, Jean Jacques, Hulme, Christopher, Jampilek, Josef, Li, Wei, Prokai-Tatrai, Katalin, Rautio, Jarkko, Collina, Simona, Tuccinardi, Tiziano, Sousa, Maria Emília, Sabatier, Jean-Marc, Galdiero, Stefania, Karaman, Rafik, Kokotos, George, Torri, Giangiacomo, Luque, F. Javier, Vasconcelos, M. Helena, Hadjipavlou-Litina, Dimitra, Siciliano, Carlo, Gütschow, Michael, Ragno, Rino, Gomes, Paula A. C., Agrofoglio, Luigi A., Muñoz-Torrero, Diego
Publicado 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5

por Mangoni, Arduino A., Eynde, Jean Jacques Vanden, Jampilek, Josef, Hadjipavlou-Litina, Dimitra, Liu, Hong, Reynisson, Jóhannes, Sousa, Maria Emília, Gomes, Paula A. C., Prokai-Tatrai, Katalin, Tuccinardi, Tiziano, Sabatier, Jean-Marc, Luque, F. Javier, Rautio, Jarkko, Karaman, Rafik, Vasconcelos, M. Helena, Gemma, Sandra, Galdiero, Stefania, Hulme, Christopher, Collina, Simona, Gütschow, Michael, Kokotos, George, Siciliano, Carlo, Capasso, Raffaele, Agrofoglio, Luigi A., Ragno, Rino, Muñoz-Torrero, Diego
Publicado 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

por Vanden Eynde, Jean Jacques, Mangoni, Arduino A., Rautio, Jarkko, Leprince, Jérôme, Azuma, Yasu-Taka, García-Sosa, Alfonso T., Hulme, Christopher, Jampilek, Josef, Karaman, Rafik, Li, Wei, Gomes, Paula A. C., Hadjipavlou-Litina, Dimitra, Capasso, Raffaele, Geronikaki, Athina, Cerchia, Laura, Sabatier, Jean-Marc, Ragno, Rino, Tuccinardi, Tiziano, Trabocchi, Andrea, Winum, Jean-Yves, Luque, F. Javier, Prokai-Tatrai, Katalin, Spetea, Mariana, Gütschow, Michael, Kosalec, Ivan, Guillou, Catherine, Vasconcelos, M. Helena, Kokotos, George, Rastelli, Giulio, de Sousa, Maria Emília, Manera, Clementina, Gemma, Sandra, Mangani, Stefano, Siciliano, Carlo, Galdiero, Stefania, Liu, Hong, Scott, Peter J. H., de los Ríos, Cristóbal, Agrofoglio, Luigi A., Collina, Simona, Guedes, Rita C., Muñoz-Torrero, Diego
Publicado 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

por Gütschow, Michael, Vanden Eynde, Jean Jacques, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino A., Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter J. H., Reynisson, Jóhannes, Rapposelli, Simona, Galdiero, Stefania, Winum, Jean-Yves, Brullo, Chiara, Prokai-Tatrai, Katalin, Sharma, Arun K., Schapira, Matthieu, Azuma, Yasu-Taka, Cerchia, Laura, Spetea, Mariana, Torri, Giangiacomo, Collina, Simona, Geronikaki, Athina, García-Sosa, Alfonso T., Vasconcelos, M. Helena, Sousa, Maria Emília, Kosalec, Ivan, Tuccinardi, Tiziano, Duarte, Iola F., Salvador, Jorge A. R., Bertinaria, Massimo, Pellecchia, Maurizio, Amato, Jussara, Rastelli, Giulio, Gomes, Paula A. C., Guedes, Rita C., Sabatier, Jean-Marc, Estévez-Braun, Ana, Pagano, Bruno, Mangani, Stefano, Ragno, Rino, Kokotos, George, Brindisi, Margherita, González, Florenci V., Borges, Fernanda, Miloso, Mariarosaria, Rautio, Jarkko, Muñoz-Torrero, Diego
Publicado 2020