Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer’s disease

por Wang, Qi, Chen, Kewei, Su, Yi, Reiman, Eric M., Dudley, Joel T., Readhead, Benjamin
Publicado 2021

Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer’s disease and implicate its dynamic role in disease progression

por Wang, Qi, Chen, Yinghua, Readhead, Benjamin, Chen, Kewei, Su, Yi, Reiman, Eric M., Dudley, Joel T.
Publicado 2020

Reduced PIN1 gene expression in neocortical and limbic brain regions in female Alzheimer’s patients correlates with cognitive and neuropathological phenotypes

por de Ávila, Camila, Suazo, Crystal, Nolz, Jennifer, Cochran, J. Nicholas, Wang, Qi, Velazquez, Ramon, Dammer, Eric, Readhead, Benjamin, Mastroeni, Diego
Publicado 2023

Reliable multiplex generation of pooled induced pluripotent stem cells

por Smullen, Molly, Olson, Meagan N., Reichert, Julia M., Dawes, Pepper, Murray, Liam F., Baer, Christina E., Wang, Qi, Readhead, Benjamin, Church, George M., Lim, Elaine T., Chan, Yingleong
Publicado 2023

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis

por Bhattacharya, Dipankar, Becker, Christine, Readhead, Benjamin, Goossens, Nicolas, Novik, Jacqueline, Fiel, Maria Isabel, Cousens, Leslie P., Magnusson, Björn, Backmark, Anna, Hicks, Ryan, Dudley, Joel T., Friedman, Scott L.
Publicado 2021

Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach

por Li, Li, Greene, Ilana, Readhead, Benjamin, Menon, Madhav C., Kidd, Brian A., Uzilov, Andrew V., Wei, Chengguo, Philippe, Nimrod, Schroppel, Bernd, He, John Cijiang, Chen, Rong, Dudley, Joel T., Murphy, Barbara
Publicado 2017

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

por Readhead, Benjamin, Hartley, Brigham J., Eastwood, Brian J., Collier, David A., Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T., Schadt, Eric E., Savić, Radoslav, Brennand, Kristen J.
Publicado 2018

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

por Readhead, Benjamin, Hartley, Brigham J., Eastwood, Brian J., Collier, David A., Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T., Schadt, Eric E., Savić, Radoslav, Brennand, Kristen J.
Publicado 2018

Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G

por Smullen, Molly, Olson, Meagan N., Murray, Liam F., Suresh, Madhusoodhanan, Yan, Guang, Dawes, Pepper, Barton, Nathaniel J., Mason, Jivanna N., Zhang, Yucheng, Fernandez-Fontaine, Aria A., Church, George M., Mastroeni, Diego, Wang, Qi, Lim, Elaine T., Chan, Yingleong, Readhead, Benjamin
Publicado 2023

Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease

por Serrano, Geidy E., Walker, Jessica E., Arce, Richard, Glass, Michael J., Vargas, Daisy, Sue, Lucia I., Intorcia, Anthony J., Nelson, Courtney M., Oliver, Javon, Papa, Jaclyn, Russell, Aryck, Suszczewicz, Katsuko E., Borja, Claryssa I., Belden, Christine, Goldfarb, Danielle, Shprecher, David, Atri, Alireza, Adler, Charles H., Shill, Holly A., Driver-Dunckley, Erika, Mehta, Shyamal H., Readhead, Benjamin, Huentelman, Matthew J., Peters, Joseph L., Alevritis, Ellie, Bimi, Christian, Mizgerd, Joseph P., Reiman, Eric M., Montine, Thomas J., Desforges, Marc, Zehnder, James L., Sahoo, Malaya K., Zhang, Haiyu, Solis, Daniel, Pinsky, Benjamin A., Deture, Michael, Dickson, Dennis W., Beach, Thomas G.
Publicado 2021