Pre-clinical modeling of cutaneous melanoma

por Rebecca, Vito W., Somasundaram, Rajasekharan, Herlyn, Meenhard
Publicado 2020

Dimeric quinacrines as chemical tools to identify PPT1, a new regulator of autophagy in cancer cells

por Nicastri, Michael C., Rebecca, Vito W., Amaravadi, Ravi K., Winkler, Jeffrey D.
Publicado 2017

Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma

por Das, Ishani, Chen, Huiqin, Maddalo, Gianluca, Tuominen, Rainer, Rebecca, Vito W., Herlyn, Meenhard, Hansson, Johan, Davies, Michael A., Egyházi Brage, Suzanne
Publicado 2020

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

por John, Jobin K., Paraiso, Kim H.T., Rebecca, Vito W., Cantini, Liliana P., Abel, Ethan V., Pagano, Nicholas, Meggers, Eric, Mathew, Rahel, Krepler, Clemens, Izumi, Victoria, Fang, Bin, Koomen, John M., Messina, Jane L., Herlyn, Meenhard, Smalley, Keiran S. M.
Publicado 2012

Dasatinib Resensitizes MAPK Inhibitor Efficacy in Standard-of-Care Relapsed Melanomas

por Rebecca, Vito W., Xiao, Min, Kossenkov, Andrew, Godok, Tetiana, Brown, Gregory Schuyler, Fingerman, Dylan, Alicea, Gretchen M., Wei, Meihan, Ji, Hongkai, Bravo, Jeremy, Chen, Yeqing, Fane, Mitchell E., Villanueva, Jessie, Nathanson, Katherine, Liu, Qin, Gopal, Y. N. Vashisht, Davies, Michael A., Herlyn, Meenhard
Publicado 2023

NUMB as a Therapeutic Target for Melanoma

por Hristova, Denitsa M., Fukumoto, Takeshi, Takemori, Chihiro, Gao, Le, Hua, Xia, Wang, Joshua X., Li, Ling, Beqiri, Marilda, Watters, Andrea, Vultur, Adina, Gimie, Yusra, Rebecca, Vito, Samarkina, Anastasia, Jimbo, Haruki, Nishigori, Chikako, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Somasundaram, Rajasekharan, Fukunaga-Kalabis, Mizuho, Herlyn, Meenhard
Publicado 2022

ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma

por Rebecca, Vito, Jagirdar, Kasturee, Portuallo, Marie, Wei, Meihan, Wilhide, Matthew, Bravo, Jeremy, Robertson, Bailey, Alicea, Gretchen, Aguh, Crsytal, Xiao, Min, Godok, Tetiana, Fingerman, Dylan, Brown, Gregory, Herlyn, Meenhard, Guo, Brian, Toska, Eneda, Zabransky, Daniel, Wubbenhorst, Bradley, Nathanson, Katherine, Kwatra, Shawn, Goyal, Yogesh, Ji, Hongkai, Liu, Qin
Publicado 2023

Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma

por Wang, Beike, Zhang, Wei, Zhang, Gao, Kwong, Lawrence, Lu, Hezhe, Tan, Jiufeng, Sadek, Norah, Xiao, Min, Zhang, Jie, Labrie, Marilyne, Randell, Sergio, Beroard, Aurelie, Sugarman, Eric, Rebecca, Vito W., Wei, Zhi, Lu, Yiling, Mills, Gordon B., Field, Jeffrey, Villanueva, Jessie, Xu, Xiaowei, Herlyn, Meenhard, Guo, Wei
Publicado 2021

Single-cell RNA sequencing reveals dysregulated fibroblast subclusters in prurigo nodularis

por Patel, Jay R., Joel, Marina Z., Lee, Kevin K., Kambala, Anusha, Cornman, Hannah, Oladipo, Olusola, Taylor, Matthew, Deng, June, Parthasarathy, Varsha, Cravero, Karen, Marani, Melika, Zhao, Ryan, Sankararam, Sreenidhi, Li, Ruixiang, Pritchard, Thomas, Rebecca, Vito, Kwatra, Madan M., Ho, Won Jin, Dong, Xinzhong, Kang, Sewon, Kwatra, Shawn G.
Publicado 2023

PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

por Sharma, Gaurav, Ojha, Rani, Noguera-Ortega, Estela, Rebecca, Vito W., Attanasio, John, Liu, Shujing, Piao, Shengfu, Lee, Jennifer J., Nicastri, Michael C., Harper, Sandra L., Ronghe, Amruta, Jain, Vaibhav, Winkler, Jeffrey D., Speicher, David W., Mastio, Jerome, Gimotty, Phyllis A., Xu, Xiaowei, Wherry, E. John, Gabrilovich, Dmitry I., Amaravadi, Ravi K.
Publicado 2020

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

por Capparelli, Claudia, Purwin, Timothy J., Glasheen, McKenna, Caksa, Signe, Tiago, Manoela, Wilski, Nicole, Pomante, Danielle, Rosenbaum, Sheera, Nguyen, Mai Q., Cai, Weijia, Franco-Barraza, Janusz, Zheng, Richard, Kumar, Gaurav, Chervoneva, Inna, Shimada, Ayako, Rebecca, Vito W., Snook, Adam E., Hookim, Kim, Xu, Xiaowei, Cukierman, Edna, Herlyn, Meenhard, Aplin, Andrew E.
Publicado 2022

PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

por Sharma, Gaurav, Ojha, Rani, Noguera-Ortega, Estela, Rebecca, Vito W., Attanasio, John, Liu, Shujing, Piao, Shengfu, Lee, Jennifer J., Nicastri, Michael C., Harper, Sandra L., Ronghe, Amruta, Jain, Vaibhav, Winkler, Jeffrey D., Speicher, David W., Mastio, Jerome, Gimotty, Phyllis A., Xu, Xiaowei, Wherry, E. John, Gabrilovich, Dmitry I., Amaravadi, Ravi K.
Publicado 2022

Persister state-directed transitioning and vulnerability in melanoma

por Chauvistré, Heike, Shannan, Batool, Daignault-Mill, Sheena M., Ju, Robert J., Picard, Daniel, Egetemaier, Stefanie, Váraljai, Renáta, Gibhardt, Christine S., Sechi, Antonio, Kaschani, Farnusch, Keminer, Oliver, Stehbens, Samantha J., Liu, Qin, Yin, Xiangfan, Jeyakumar, Kirujan, Vogel, Felix C. E., Krepler, Clemens, Rebecca, Vito W., Kubat, Linda, Lueong, Smiths S., Forster, Jan, Horn, Susanne, Remke, Marc, Ehrmann, Michael, Paschen, Annette, Becker, Jürgen C., Helfrich, Iris, Rauh, Daniel, Kaiser, Markus, Gul, Sheraz, Herlyn, Meenhard, Bogeski, Ivan, Rodríguez-López, José Neptuno, Haass, Nikolas K., Schadendorf, Dirk, Roesch, Alexander
Publicado 2022

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

por Liu, Jianglan, Rebecca, Vito W., Kossenkov, Andrew V., Connelly, Thomas, Liu, Qin, Gutierrez, Alexis, Xiao, Min, Li, Ling, Zhang, Gao, Samarkina, Anastasia, Zayasbazan, Delaine, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Alicea, Gretchen M., Fukunaga-Kalabis, Mizuho, Krepler, Clemens, Aza-Blanc, Pedro, Yang, Chih-Cheng, Delvadia, Bela, Tong, Cynthia, Huang, Ye, Delvadia, Maya, Morias, Alice S., Sproesser, Katrin, Brafford, Patricia, Wang, Joshua X., Beqiri, Marilda, Somasundaram, Rajasekharan, Vultur, Adina, Hristova, Denitsa M., Wu, Lawrence W., Lu, Yiling, Mills, Gordon B., Xu, Wei, Karakousis, Giorgos C., Xu, Xiaowei, Schuchter, Lynn M., Mitchell, Tara C., Amaravadi, Ravi K., Kwong, Lawrence N., Frederick, Dennie T., Boland, Genevieve M., Salvino, Joseph M., Speicher, David W., Flaherty, Keith T., Ronai, Ze'ev A., Herlyn, Meenhard
Publicado 2021

Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy

por Somasundaram, Rajasekharan, Connelly, Thomas, Choi, Robin, Choi, Hyeree, Samarkina, Anastasia, Li, Ling, Gregorio, Elizabeth, Chen, Yeqing, Thakur, Rohit, Abdel-Mohsen, Mohamed, Beqiri, Marilda, Kiernan, Meaghan, Perego, Michela, Wang, Fang, Xiao, Min, Brafford, Patricia, Yang, Xue, Xu, Xiaowei, Secreto, Anthony, Danet-Desnoyers, Gwenn, Traum, Daniel, Kaestner, Klaus H., Huang, Alexander C., Hristova, Denitsa, Wang, Joshua, Fukunaga-Kalabis, Mizuho, Krepler, Clemens, Ping-Chen, Fang, Zhou, Xiangyang, Gutierrez, Alexis, Rebecca, Vito W., Vonteddu, Prashanthi, Dotiwala, Farokh, Bala, Shashi, Majumdar, Sonali, Dweep, Harsh, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Reyes-Arbujas, Jorge, Santiago, Kenisha, Nguyen, Tran, Griss, Johannes, Keeney, Frederick, Hayden, James, Gavin, Brian J., Weiner, David, Montaner, Luis J., Liu, Qin, Peiffer, Lukas, Becker, Jürgen, Burton, Elizabeth M., Davies, Michael A., Tetzlaff, Michael T., Muthumani, Kar, Wargo, Jennifer A., Gabrilovich, Dmitry, Herlyn, Meenhard
Publicado 2021

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

por Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.
Publicado 2021

Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

por Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.
Publicado 2021