Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase

por Rechkoblit, Olga, Kolbanovskiy, Alexander, Landes, Hannah, Geacintov, Nicholas E., Aggarwal, Aneel K.
Publicado 2017

Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studie...

por Zhang, Ling, Rechkoblit, Olga, Wang, Lihua, Patel, Dinshaw J., Shapiro, Robert, Broyde, Suse
Publicado 2006

Mechanism of error-free and semi-targeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4

por Rechkoblit, Olga, Kolbanovskiy, Alexander, Malinina, Lucy, Geacintov, Nicholas E., Broyde, Suse, Patel, Dinshaw J.
Publicado 2010

Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine

por Rechkoblit, Olga, Choudhury, Jayati Roy, Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2018

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η

por Rechkoblit, Olga, Johnson, Robert E., Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2019

Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase

por Rechkoblit, Olga, Johnson, Robert E., Gupta, Yogesh K., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2021

Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion

por Rechkoblit, Olga, Malinina, Lucy, Cheng, Yuan, Kuryavyi, Vitaly, Broyde, Suse, Geacintov, Nicholas E, Patel, Dinshaw J
Publicado 2006

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity

por Rechkoblit, Olga, Gupta, Yogesh K., Malik, Radhika, Rajashankar, Kanagalaghatta R., Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2016

Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals

por Kottur, Jithesh, White, Kris M., Rodriguez, M. Luis, Rechkoblit, Olga, Quintana-Feliciano, Richard, Nayar, Ahana, García-Sastre, Adolfo, Aggarwal, Aneel K.
Publicado 2023

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

por Ummat, Ajay, Rechkoblit, Olga, Jain, Rinku, Choudhary, Jayati R., Johnson, Robert E., Silverstein, Timothy D., Buku, Angeliki, Lone, Samer, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2012

Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblast...

por Padgaonkar, Amol, Rechkoblit, Olga, Vasquez-Del Carpio, Rodgrigo, Pallela, Venkat, Venkata Subbaiah, DRC, Cosenza, Stephen C., Baker, Stacey J., Ramana Reddy, M.V., Aggarwal, Aneel, Reddy, E. Premkumar
Publicado 2018

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

por Sato, Katsutoshi, Padgaonkar, Amol A., Baker, Stacey J., Cosenza, Stephen C., Rechkoblit, Olga, Subbaiah, D. R. C. Venkata, Domingo-Domenech, Josep, Bartkowski, Alison, Port, Elisa R., Aggarwal, Aneel K., Ramana Reddy, M. V., Irie, Hanna Y., Reddy, E. Premkumar
Publicado 2021