Looking ahead in early-phase trial design to improve the drug development process: examples in oncology

por Vanderbeek, Alyssa M., Redd, Robert A., Ventz, Steffen, Trippa, Lorenzo
Publicado 2023

Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing

por ten Hacken, Elisa, Gruber, Michaela, Hernández-Sánchez, María, Hoffmann, Gabriela Brunsting, Baranowski, Kaitlyn, Redd, Robert A., Clement, Kendell, Livak, Kenneth, Wu, Catherine J.
Publicado 2023

KMDATA: a curated database of reconstructed individual patient-level data from 153 oncology clinical trials

por Fell, Geoffrey, Redd, Robert A, Vanderbeek, Alyssa M, Rahman, Rifaquat, Louv, Bill, McDunn, Jon, Arfè, Andrea, Alexander, Brian M, Ventz, Steffen, Trippa, Lorenzo
Publicado 2021

Phase 1 open-label study of panobinostat, lenalidomide, bortezomib + dexamethasone in relapsed and relapsed/refractory multiple myeloma

por Laubach, Jacob P., Tuchman, Sascha A., Rosenblatt, Jacalyn M., Mitsiades, Constantine S., Colson, Kathleen, Masone, Kelly, Warren, Diane, Redd, Robert A., Grayson, Dena, Richardson, Paul G.
Publicado 2021

P1207: SERIAL SINGLE-CELL PROFILING OF MANTLE CELL LYMPHOMA REVEALS FUNCTIONAL AND MOLECULAR CORRELATES OF RESISTANCE TO BTK INHIBITOR-INCLUSIVE TRIPLET THERAPY

por Debaize, Lydie, Zhang, Ye, Ramseier, Michelle, Zhang, Mingzeng, Langenbucher, Adam, Winter, Peter S., Xu, Ran, Senhaji, Nezha, Redd, Robert A, Aryee, Martin J., Branch, Paul H., Kim, Austin I., Weinstock, David M., Shalek, Alex, Manalis, Scott R., Murakami, Mark A.
Publicado 2023

Risks for Hospitalization and Death Among Patients with Blood Disorders from the ASH RC COVID-19 Registry for Hematology

por Hicks, Lisa K., Redd, Robert A., Anderson, Kenneth C., Desai, Pinkal, Dolan, Brendan, Goldberg, Aaron D, Narendra, Varun, Neuberg, Donna S., Radhakrishnan, Vivek, Sehn, Laurie H., Sekeres, Mikkael A., Stahl, Maximilian, Tallman, Martin S., Thompson, John Colton, Tucker, Emily, Wood, William A.
Publicado 2021

Clinical Predictors of Outcome in Adult Patients with Acute Leukemias and Myelodysplastic Syndrome and COVID-19 Infection: Report from the American Society of Hematology Research C...

por Desai, Pinkal, Goldberg, Aaron D, Anderson, Kenneth C., Narendra, Varun, Neuberg, Donna S., Radhakrishnan, Vivek, Redd, Robert A., Roboz, Gail J., Sehn, Laurie H., Sekeres, Mikkael A., Stahl, Maximilian, Tallman, Martin S., Thompson, John Colton, Tucker, Emily, Wood, William A., Hicks, Lisa K.
Publicado 2021

Attenuated response to SARS-CoV-2 vaccine in patients with asymptomatic precursor stages of multiple myeloma and Waldenstrom macroglobulinemia

por Konishi, Yoshinobu, Sklavenitis-Pistofidis, Romanos, Yue, Hong, Ferrari, Federico, Redd, Robert A., Lightbody, Elizabeth D., Russo, Massimiliano, Perry, Jacqueline, Horowitz, Erica, Justis, Anna V., Shayegh, Nader A., Savell, Alexandra, Prescott, Julia, Varmeh, Shohreh, Nowak, Radosław P., Hamilton, Mark, Auclair, Daniel, Marinac, Catherine R., Trippa, Lorenzo, Fischer, Eric S., Ghobrial, Irene M.
Publicado 2022

Minimal residual disease in patients with diffuse large B-cell lymphoma undergoing autologous stem cell transplantation

por Merryman, Reid W., Redd, Robert A., Taranto, Eleanor, Ahmed, Gulrayz, Jeter, Erin, McHugh, Kristin M., Brown, Jennifer R., Crombie, Jennifer L., Davids, Matthew S., Fisher, David C., Freedman, Arnold S., Jacobsen, Eric, Jacobson, Caron A., Kim, Austin I., LaCasce, Ann S., Ng, Samuel Y., Odejide, Oreofe O., Parry, Erin M., Jacene, Heather, Park, Hyesun, Dahi, Parastoo B., Nieto, Yago, Joyce, Robin M., Chen, Yi-Bin, Shipp, Margaret A., Herrera, Alex F., Armand, Philippe
Publicado 2022

Humoral and cellular immunogenicity of SARS-CoV-2 vaccines in chronic lymphocytic leukemia: a prospective cohort study

por Haydu, J. Erika, Maron, Jenny S., Redd, Robert A., Gallagher, Kathleen M. E., Fischinger, Stephanie, Barnes, Jeffrey A., Hochberg, Ephraim P., Johnson, P. Connor, Takvorian, R. W., Katsis, Katelin, Portman, Daneal, Ruiters, Jade, Sechio, Sidney, Devlin, Mary, Regan, Connor, Blumenthal, Kimberly G., Banerji, Aleena, Judd, Allen D., Scorsune, Krista J., McGree, Brianne M., Sherburne, Maryanne M., Lynch, Julia M., Weitzman, James I., Lei, Matthew, Kotton, Camille N., Dighe, Anand S., Maus, Marcela V., Alter, Galit, Abramson, Jeremy S., Soumerai, Jacob D.
Publicado 2022