DNA methylation reprogramming in cancer: Does it act by re-configuring the binding landscape of Polycomb repressive complexes?

por Reddington, James P, Sproul, Duncan, Meehan, Richard R
Publicado 2014

scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation

por Heinen, Tobias, Secchia, Stefano, Reddington, James P., Zhao, Bingqing, Furlong, Eileen E. M., Stegle, Oliver
Publicado 2022

The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in...

por Brook, Matthew, McCracken, Lora, Reddington, James P., Lu, Zhi-Liang, Morrice, Nicholas A., Gray, Nicola K.
Publicado 2012

The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice

por Reichmann, Judith, Reddington, James P., Best, Diana, Read, David, Öllinger, Rupert, Meehan, Richard R., Adams, Ian R.
Publicado 2013

The Role of Chromatin Accessibility in cis-Regulatory Evolution

por Peng, Pei-Chen, Khoueiry, Pierre, Girardot, Charles, Reddington, James P, Garfield, David A, Furlong, Eileen E M, Sinha, Saurabh
Publicado 2019

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

por Liu, Jialin, Viales, Rebecca R., Khoueiry, Pierre, Reddington, James P., Girardot, Charles, Furlong, Eileen E.M., Robinson-Rechavi, Marc
Publicado 2021

Apoptosis and DNA Methylation

por Meng, Huan X., Hackett, James A., Nestor, Colm, Dunican, Donncha S., Madej, Monika, Reddington, James P., Pennings, Sari, Harrison, David J., Meehan, Richard R.
Publicado 2011

The cis-regulatory dynamics of embryonic development at single cell resolution

por Cusanovich, Darren A., Reddington, James P., Garfield, David A., Daza, Riza, Aghamirzaie, Delasa, Marco-Ferreres, Raquel, Pliner, Hannah, Christiansen, Lena, Qiu, Xiaojie, Steemers, Frank J., Trapnell, Cole, Shendure, Jay, Furlong, Eileen E.M.
Publicado 2018

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

por Reddington, James P, Perricone, Sara M, Nestor, Colm E, Reichmann, Judith, Youngson, Neil A, Suzuki, Masako, Reinhardt, Diana, Dunican, Donncha S, Prendergast, James G, Mjoseng, Heidi, Ramsahoye, Bernard H, Whitelaw, Emma, Greally, John M, Adams, Ian R, Bickmore, Wendy A, Meehan, Richard R
Publicado 2013