JNK-signaling: A multiplexing hub in programmed cell death

por Dhanasekaran, Danny N., Reddy, E. Premkumar
Publicado 2017

CDK4: a master regulator of the cell cycle and its role in cancer

por Baker, Stacey J., Poulikakos, Poulikos I., Irie, Hanna Y., Parekh, Samir, Reddy, E. Premkumar
Publicado 2022

ON01210.Na (Ex-RAD(®)) Mitigates Radiation Damage through Activation of the AKT Pathway

por Kang, Anthony D., Cosenza, Stephen C., Bonagura, Marie, Manair, Manoj, Reddy, M. V. Ramana, Reddy, E. Premkumar
Publicado 2013

TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis

por Xia, Yuhan, Inoue, Kazuki, Du, Yong, Baker, Stacey J., Reddy, E. Premkumar, Greenblatt, Matthew B., Zhao, Baohong
Publicado 2022

Activation of p38α/β MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo

por Takaesu, Giichi, Kang, Jong-Sun, Bae, Gyu-Un, Yi, Min-Jeong, Lee, Clement M., Reddy, E. Premkumar, Krauss, Robert S.
Publicado 2006

Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component muta...

por Troilo, Albino, Benson, Erica K., Esposito, Davide, Garibsingh, Rachel-Ann A., Reddy, E. Premkumar, Mungamuri, Sathish Kumar, Aaronson, Stuart A.
Publicado 2016

Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer

por Ha, Ji Hee, Yan, Mingda, Gomathinayagam, Rohini, Jayaraman, Muralidharan, Husain, Sanam, Liu, Jinsong, Mukherjee, Priyabrata, Reddy, E. Premkumar, Song, Yong Sang, Dhanasekaran, Danny N.
Publicado 2016

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression

por Chen, Xu-Qiao, Barrero, Carlos A., Vasquez-Del Carpio, Rodrigo, Reddy, E. Premkumar, Fecchio, Chiara, Merali, Salim, Deglincerti, Alessia, Fang, Cheng, Rogers, Jack, Maccecchini, Maria L.
Publicado 2021

Dual Inhibition of CDK4/Rb and PI3K/AKT/mTOR Pathways by ON123300 Induces Synthetic Lethality in Mantle Cell Lymphomas

por Divakar, Saikrishna A., Reddy, M.V. Ramana, Cosenza, Stephen C., Baker, Stacey J., Perumal, Deepak, Antonelli, Anthony C., Brody, Joshua, Akula, Balaiah, Parekh, Samir, Reddy, E. Premkumar
Publicado 2015

Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblast...

por Padgaonkar, Amol, Rechkoblit, Olga, Vasquez-Del Carpio, Rodgrigo, Pallela, Venkat, Venkata Subbaiah, DRC, Cosenza, Stephen C., Baker, Stacey J., Ramana Reddy, M.V., Aggarwal, Aneel, Reddy, E. Premkumar
Publicado 2018

Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade

por Yan, Chi, Saleh, Nabil, Yang, Jinming, Nebhan, Caroline A., Vilgelm, Anna E., Reddy, E. Premkumar, Roland, Joseph T., Johnson, Douglas B., Chen, Sheau-Chiann, Shattuck-Brandt, Rebecca L., Ayers, Gregory D., Richmond, Ann
Publicado 2021

Epigenetic Silencing of β-Spectrin, a TGF-β Signaling/Scaffolding Protein in a Human Cancer Stem Cell Disorder: BECKWITH-WIEDEMANN SYNDROME

por Yao, Zhi-Xing, Jogunoori, Wilma, Choufani, Sanaa, Rashid, Asif, Blake, Tiffany, Yao, Wenguo, Kreishman, Peter, Amin, Rupen, Sidawy, Anton A., Evans, Stephen R. T., Finegold, Milton, Reddy, E. Premkumar, Mishra, Bibhuti, Weksberg, Rosanna, Kumar, Rakesh, Mishra, Lopa
Publicado 2010

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

por Sato, Katsutoshi, Padgaonkar, Amol A., Baker, Stacey J., Cosenza, Stephen C., Rechkoblit, Olga, Subbaiah, D. R. C. Venkata, Domingo-Domenech, Josep, Bartkowski, Alison, Port, Elisa R., Aggarwal, Aneel K., Ramana Reddy, M. V., Irie, Hanna Y., Reddy, E. Premkumar
Publicado 2021

Discovery of 8-Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinas...

por Reddy, M. V. Ramana, Akula, Balireddy, Cosenza, Stephen C., Athuluridivakar, Saikrishna, Mallireddigari, Muralidhar R., Pallela, Venkat R., Billa, Vinay K., Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Vasquez-Del Carpio, Rodrigo, Padgaonkar, Amol, Baker, Stacey J., Reddy, E. Premkumar
Publicado 2014