Genomic approaches for understanding the genetics of complex disease

por Lowe, William L., Reddy, Timothy E.
Publicado 2015

Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites

por Reddy, Timothy E, DeLisi, Charles, Shakhnovich, Boris E
Publicado 2007

Functional Genomics of Healthy and Pathological Fetal Membranes

por Cunningham, Sarah J., Feng, Liping, Allen, Terrence K., Reddy, Timothy E.
Publicado 2020

Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABA(A) receptor subunit genes

por Reddy, Timothy E., Shakhnovich, Boris E., Roberts, Daniel S., Russek, Shelley J., DeLisi, Charles
Publicado 2007

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

por Gertz, Jason, Reddy, Timothy E., Varley, Katherine E., Garabedian, Michael J., Myers, Richard M.
Publicado 2012

ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection

por Zhu, Xinyu, Trimarco, Joseph D., Williams, Courtney A., Barrera, Alejandro, Reddy, Timothy E., Heaton, Nicholas S.
Publicado 2022

New Insights Into Gestational Glucose Metabolism: Lessons Learned From 21st Century Approaches

por Angueira, Anthony R., Ludvik, Anton E., Reddy, Timothy E., Wicksteed, Barton, Lowe, William L., Layden, Brian T.
Publicado 2015

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

por Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015

Clustering gene expression time series data using an infinite Gaussian process mixture model

por McDowell, Ian C., Manandhar, Dinesh, Vockley, Christopher M., Schmid, Amy K., Reddy, Timothy E., Engelhardt, Barbara E.
Publicado 2018

Transversions have larger regulatory effects than transitions

por Guo, Cong, McDowell, Ian C., Nodzenski, Michael, Scholtens, Denise M., Allen, Andrew S., Lowe, William L., Reddy, Timothy E.
Publicado 2017

AP-1 subunits converge promiscuously at enhancers to potentiate transcription

por Seo, Jungkyun, Koçak, D. Dewran, Bartelt, Luke C., Williams, Courtney A., Barrera, Alejandro, Gersbach, Charles A., Reddy, Timothy E.
Publicado 2021

Genome-wide quantification of the effects of DNA methylation on human gene regulation

por Lea, Amanda J, Vockley, Christopher M, Johnston, Rachel A, Del Carpio, Christina A, Barreiro, Luis B, Reddy, Timothy E, Tung, Jenny
Publicado 2018

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers

por Hilton, Isaac B., D’Ippolito, Anthony M., Vockley, Christopher M., Thakore, Pratiksha I., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2015

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

por Vockley, Christopher M., Guo, Cong, Majoros, William H., Nodzenski, Michael, Scholtens, Denise M., Hayes, M. Geoffrey, Lowe, William L., Reddy, Timothy E.
Publicado 2015

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

por Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Perez-Pinera, Pablo, Brown, Matthew T, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A
Publicado 2015

Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain

por Kabadi, Ami M., Thakore, Pratiksha I., Vockley, Christopher M., Ousterout, David G., Gibson, Tyler M., Guilak, Farshid, Reddy, Timothy E., Gersbach, Charles A.
Publicado 2014

CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

por Klann, Tyler S., Black, Joshua B., Chellappan, Malathi, Safi, Alexias, Song, Lingyun, Hilton, Isaac B., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publicado 2017

c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program

por Parker, Morgan E., Barrera, Alejandro, Wheaton, Joshua D., Zuberbuehler, Matthew K., Allan, David S.J., Carlyle, James R., Reddy, Timothy E., Ciofani, Maria
Publicado 2019

Correcting signal biases and detecting regulatory elements in STARR-seq data

por Kim, Young-Sook, Johnson, Graham D., Seo, Jungkyun, Barrera, Alejandro, Cowart, Thomas N., Majoros, William H., Ochoa, Alejandro, Allen, Andrew S., Reddy, Timothy E.
Publicado 2021

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

por Gertz, Jason, Varley, Katherine E., Reddy, Timothy E., Bowling, Kevin M., Pauli, Florencia, Parker, Stephanie L., Kucera, Katerina S., Willard, Huntington F., Myers, Richard M.
Publicado 2011