Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt

por Dutton, Louise R., Hoare, Owen P., McCorry, Amy M.B., Redmond, Keara L., Adam, Noor Eisa, Canamara, Shannon, Bingham, Victoria, Mullan, Paul B., Lawler, Mark, Dunne, Philip D., Brazil, Derek P.
Publicado 2019

Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data

por Ahmaderaghi, Baharak, Amirkhah, Raheleh, Jackson, James, Lannagan, Tamsin R. M., Gilroy, Kathryn, Malla, Sudhir B., Redmond, Keara L., Quinn, Gerard, McDade, Simon S., ACRCelerate Consortium, Maughan, Tim, Leedham, Simon, Campbell, Andrew S. D., Sansom, Owen J., Lawler, Mark, Dunne, Philip D.
Publicado 2022

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

por Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H
Publicado 2021

Biological Misinterpretation of Transcriptional Signatures in Tumor Samples Can Unknowingly Undermine Mechanistic Understanding and Faithful Alignment with Preclinical Data

por Fisher, Natalie C., Byrne, Ryan M., Leslie, Holly, Wood, Colin, Legrini, Assya, Cameron, Andrew J., Ahmaderaghi, Baharak, Corry, Shania M., Malla, Sudhir B., Amirkhah, Raheleh, McCooey, Aoife J., Rogan, Emily, Redmond, Keara L., Sakhnevych, Svetlana, Domingo, Enric, Jackson, James, Loughrey, Maurice B., Leedham, Simon, Maughan, Tim, Lawler, Mark, Sansom, Owen J., Lamrock, Felicity, Koelzer, Viktor H., Jamieson, Nigel B., Dunne, Philip D.
Publicado 2022

Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer

por Corry, Shania M, McCorry, Amy MB, Lannagan, Tamsin RM, Leonard, Niamh A, Fisher, Natalie C, Byrne, Ryan M, Tsantoulis, Petros, Cortes-Lavaud, Xabier, Amirkhah, Raheleh, Redmond, Keara L, McCooey, Aoife J, Malla, Sudhir B, Rogan, Emily, Sakhnevych, Svetlana, Gillespie, Michael A, White, Mark, Richman, Susan D, Jackstadt, Rene-Filip, Campbell, Andrew D, Maguire, Sarah, McDade, Simon S, Longley, Daniel B, Loughrey, Maurice B, Coleman, Helen G, Kerr, Emma M, Tejpar, Sabine, Maughan, Timothy, Leedham, Simon J, Small, Donna M, Ryan, Aideen E, Sansom, Owen J, Lawler, Mark, Dunne, Philip D
Publicado 2022

Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

por Flanagan, Dustin J., Amirkhah, Raheleh, Vincent, David F., Gunduz, Nuray, Gentaz, Pauline, Cammareri, Patrizia, McCooey, Aoife J., McCorry, Amy M. B., Fisher, Natalie C., Davis, Hayley L., Ridgway, Rachel A., Lohuis, Jeroen, Leach, Joshua D. G., Jackstadt, Rene, Gilroy, Kathryn, Mariella, Elisa, Nixon, Colin, Clark, William, Hedley, Ann, Markert, Elke K., Strathdee, Douglas, Bartholin, Laurent, Redmond, Keara L., Kerr, Emma M., Longley, Daniel B., Ginty, Fiona, Cho, Sanghee, Coleman, Helen G., Loughrey, Maurice B., Bardelli, Alberto, Maughan, Timothy S., Campbell, Andrew D., Lawler, Mark, Leedham, Simon J., Barry, Simon T., Inman, Gareth J., van Rheenen, Jacco, Dunne, Philip D., Sansom, Owen J.
Publicado 2022

Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

por Flanagan, Dustin J., Amirkhah, Raheleh, Vincent, David F., Gunduz, Nuray, Gentaz, Pauline, Cammareri, Patrizia, McCooey, Aoife J., McCorry, Amy M. B., Fisher, Natalie C., Davis, Hayley L., Ridgway, Rachel A., Lohuis, Jeroen, Leach, Joshua D. G., Jackstadt, Rene, Gilroy, Kathryn, Mariella, Elisa, Nixon, Colin, Clark, William, Hedley, Ann, Markert, Elke K., Strathdee, Douglas, Bartholin, Laurent, Redmond, Keara L., Kerr, Emma M., Longley, Daniel B., Ginty, Fiona, Cho, Sanghee, Coleman, Helen G., Loughrey, Maurice B., Bardelli, Alberto, Maughan, Timothy S., Campbell, Andrew D., Lawler, Mark, Leedham, Simon J., Barry, Simon T., Inman, Gareth J., van Rheenen, Jacco, Dunne, Philip D., Sansom, Owen J.
Publicado 2023