Pretreatment of human retinal pigment epithelial cells with sterculic acid forestalls fenretinide-induced apoptosis

por William, Samuel, Duncan, Todd, Redmond, T. Michael
Publicado 2022

The dual roles of RPE65 S-palmitoylation in membrane association and visual cycle function

por Uppal, Sheetal, Liu, Tingting, Poliakov, Eugenia, Gentleman, Susan, Redmond, T. Michael
Publicado 2019

Palmitoylation of Metazoan Carotenoid Oxygenases

por Uppal, Sheetal, Rogozin, Igor B., Redmond, T.Michael, Poliakov, Eugenia
Publicado 2020

Phylogenetic analysis of the metazoan carotenoid oxygenase superfamily: a new ancestral gene assemblage of BCO-like (BCOL) proteins

por Poliakov, Eugenia, Soucy, Joseph, Gentleman, Susan, Rogozin, Igor B., Redmond, T. Michael
Publicado 2017

Stable Intronic Sequences and Exon Skipping Events in the Human RPE65 Gene: Analysis of Expression in Retinal Pigment Epithelium Cells and Cell Culture Models

por Postnikova, Olga, Poliakov, Eugenia, Golestaneh, Nady, Rogozin, Igor B., Redmond, T. Michael
Publicado 2019

Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets β-carotene o...

por Poliakov, Eugenia, Samuel, William, Duncan, Todd, Gutierrez, Danielle B., Mata, Nathan L., Redmond, T. Michael
Publicado 2017

Xanthophylls Modulate Palmitoylation of Mammalian β-Carotene Oxygenase 2

por Uppal, Sheetal, Dergunov, Sergey A., Zhang, Weiyu, Gentleman, Susan, Redmond, T. Michael, Pinkhassik, Eugene, Poliakov, Eugenia
Publicado 2021

An inducible amphipathic α-helix mediates subcellular targeting and membrane binding of RPE65

por Uppal, Sheetal, Liu, Tingting, Galvan, Emily, Gomez, Fatima, Tittley, Tishina, Poliakov, Eugenia, Gentleman, Susan, Redmond, T Michael
Publicado 2022

Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse β-carotene 15, 15'-monooxygenase

por Poliakov, Eugenia, Gentleman, Susan, Chander, Preethi, Cunningham, Francis X, Grigorenko, Bella L, Nemuhin, Alexander V, Redmond, T Michael
Publicado 2009

Volatile Evolution of Long Non-Coding RNA Repertoire in Retinal Pigment Epithelium: Insights from Comparison of Bovine and Human RNA Expression Profiles

por Postnikova, Olga A., Rogozin, Igor B., Samuel, William, Nudelman, German, Babenko, Vladimir N., Poliakov, Eugenia, Redmond, T. Michael
Publicado 2019

MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: Increased expression of microRNA-9 by N-(4-Hydroxyphenyl)retinamide

por Kutty, R. Krishnan, Samuel, William, Jaworski, Cynthia, Duncan, Todd, Nagineni, Chandrasekharam N., Raghavachari, Nalini, Wiggert, Barbara, Redmond, T. Michael
Publicado 2010

Proinflammatory cytokines decrease the expression of genes critical for RPE function

por Kutty, R. Krishnan, Samuel, William, Boyce, Kaifa, Cherukuri, Aswini, Duncan, Todd, Jaworski, Cynthia, Nagineni, Chandrasekharam N., Redmond, T. Michael
Publicado 2016

Low-Density Lipoprotein Receptor (LDLR) Is Involved in Internalization of Lentiviral Particles Pseudotyped with SARS-CoV-2 Spike Protein in Ocular Cells

por Uppal, Sheetal, Postnikova, Olga, Villasmil, Rafael, Rogozin, Igor B., Bocharov, Alexander V., Eggerman, Thomas L., Poliakov, Eugenia, Redmond, T. Michael
Publicado 2023

Origin and Evolution of Retinoid Isomerization Machinery in Vertebrate Visual Cycle: Hint from Jawless Vertebrates

por Poliakov, Eugenia, Gubin, Alexander N., Stearn, Olivia, Li, Yan, Campos, Maria Mercedes, Gentleman, Susan, Rogozin, Igor B., Redmond, T. Michael
Publicado 2012

The Functional Consequences of the Novel Ribosomal Pausing Site in SARS-CoV-2 Spike Glycoprotein RNA

por Postnikova, Olga A., Uppal, Sheetal, Huang, Weiliang, Kane, Maureen A., Villasmil, Rafael, Rogozin, Igor B., Poliakov, Eugenia, Redmond, T. Michael
Publicado 2021

Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65(-/- )knockout mouse eye results in limited rescue

por Lai, Chooi-May, Yu, Meaghan JT, Brankov, Meliha, Barnett, Nigel L, Zhou, Xiaohuai, Redmond, T Michael, Narfstrom, Kristina, Rakoczy, P Elizabeth
Publicado 2004

Multiple A2E treatments lead to melanization of rod outer segment–challenged ARPE-19 cells

por Poliakov, Eugenia, Strunnikova, Natalya V., Jiang, Jian-kang, Martinez, Bianca, Parikh, Toral, Lakkaraju, Aparna, Thomas, Craig, Brooks, Brian P., Redmond, T. Michael
Publicado 2014

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells

por Samuel, William, Jaworski, Cynthia, Postnikova, Olga. A., Kutty, R. Krishnan, Duncan, Todd, Tan, Li Xuan, Poliakov, Eugenia, Lakkaraju, Aparna, Redmond, T. Michael
Publicado 2017

Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1β, tumor necrosis factor-α, and interferon-γ

por Kutty, R. Krishnan, Nagineni, Chandrasekharam N., Samuel, William, Vijayasarathy, Camasamudram, Jaworski, Cynthia, Duncan, Todd, Cameron, Jennifer E., Flemington, Erik K., Hooks, John J., Redmond, T. Michael
Publicado 2013

CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function

por Sethna, Saumil, Scott, Patrick A., Giese, Arnaud P. J., Duncan, Todd, Jian, Xiaoying, Riazuddin, Sheikh, Randazzo, Paul A., Redmond, T. Michael, Bernstein, Steven L., Riazuddin, Saima, Ahmed, Zubair M.
Publicado 2021