Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy

por Jang, Sang-Min, Redon, Christophe E., Aladjem, Mirit I.
Publicado 2018

SOD2 deficiency promotes aging phenotypes in mouse skin

por Weyemi, Urbain, Parekh, Palak R., Redon, Christophe E., Bonner, William M.
Publicado 2012

Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

por Nakamura, Asako J., Redon, Christophe E., Bonner, William M., Sedelnikova, Olga A.
Publicado 2009

Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model

por Moroni, Maria, Maeda, Daisuke, Whitnall, Mark H., Bonner, William M., Redon, Christophe E.
Publicado 2013

Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases

por Jang, Sang-Min, Redon, Christophe E., Thakur, Bhushan L., Bahta, Meriam K., Aladjem, Mirit I.
Publicado 2020

The Use of Gamma-H2AX as a Biodosimeter for Total-Body Radiation Exposure in Non-Human Primates

por Redon, Christophe E., Nakamura, Asako J., Gouliaeva, Ksenia, Rahman, Arifur, Blakely, William F., Bonner, William M.
Publicado 2010

Evaluation of surrogate tissues as indicators of drug activity in a melanoma skin model

por Parekh, Palak R., Choudhuri, Rohini, Weyemi, Urbain, Martin, Olga A., Bonner, William M., Redon, Christophe E.
Publicado 2016

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

por Redon, Christophe E., Nakamura, Asako J., Martin, Olga A., Parekh, Palak R., Weyemi, Urbain S., Bonner, William M.
Publicado 2011

Mitochondrial Topoisomerase I is Critical for Mitochondrial Integrity and Cellular Energy Metabolism

por Douarre, Céline, Sourbier, Carole, Dalla Rosa, Ilaria, Brata Das, Benu, Redon, Christophe E., Zhang, Hongliang, Neckers, Len, Pommier, Yves
Publicado 2012

Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity

por Dickey, Jennifer S., Baird, Brandon J., Redon, Christophe E., Avdoshina, Valeriya, Palchik, Guillermo, Wu, Junfang, Kondratyev, Alexei, Bonner, William M., Martin, Olga A.
Publicado 2012

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability

por Utani, Koichi, Fu, Haiqing, Jang, Sang-Min, Marks, Anna B., Smith, Owen K., Zhang, Ya, Redon, Christophe E., Shimizu, Noriaki, Aladjem, Mirit I.
Publicado 2017

Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells

por Redon, Christophe E., Schmal, Zoe, Tewary, Gargi, Mangelinck, Adèle, Courbeyrette, Régis, Thuret, Jean-Yves, Aladjem, Mirit I., Bonner, William M., Rübe, Claudia E., Mann, Carl
Publicado 2021

SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci

por Thakur, Bhushan L., Kusi, Nana A., Mosavarpour, Sara, Zhu, Roger, Redon, Christophe E., Fu, Haiqing, Dhall, Anjali, Pongor, Lorinc S., Sebastian, Robin, Indig, Fred E., Aladjem, Mirit I.
Publicado 2023

Replication Stress Defines Distinct Molecular Subtypes Across Cancers

por Takahashi, Nobuyuki, Kim, Sehyun, Schultz, Christopher W., Rajapakse, Vinodh N., Zhang, Yang, Redon, Christophe E., Fu, Haiqing, Pongor, Lorinc, Kumar, Suresh, Pommier, Yves, Aladjem, Mirit I., Thomas, Anish
Publicado 2022

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

por Jang, Sang-Min, Zhang, Ya, Utani, Koichi, Fu, Haiqing, Redon, Christophe E., Marks, Anna B., Smith, Owen K., Redmond, Catherine J., Baris, Adrian M., Tulchinsky, Danielle A., Aladjem, Mirit I.
Publicado 2018

The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition

por Weyemi, Urbain, Redon, Christophe E., Choudhuri, Rohini, Aziz, Towqir, Maeda, Daisuke, Boufraqech, Myriem, Parekh, Palak R., Sethi, Taresh K., Kasoji, Manjula, Abrams, Natalie, Merchant, Anand, Rajapakse, Vinodh N., Bonner, William M.
Publicado 2016

BEND3 safeguards pluripotency by repressing differentiation-associated genes

por Kurniawan, Fredy, Chetlangia, Neha, Kamran, Mohammad, Redon, Christophe E., Pongor, Lorinc, Sun, Qinyu, Lin, Yo-Chuen, Mohan, Vijay, Shaqildi, Oways, Asoudegi, Darya, Hao, Qinyu, Khan, Abid, Aladjem, Mirit I., Prasanth, Kannanganattu V., Prasanth, Supriya G.
Publicado 2022

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

por Ji, Jiuping, Zhang, Yiping, Redon, Christophe E., Reinhold, William C., Chen, Alice P., Fogli, Laura K., Holbeck, Susan L., Parchment, Ralph E., Hollingshead, Melinda, Tomaszewski, Joseph E., Dudon, Quentin, Pommier, Yves, Doroshow, James H., Bonner, William M.
Publicado 2017

The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

por Jang, Sang-Min, Nathans, Jenny F., Fu, Haiqing, Redon, Christophe E., Jenkins, Lisa M., Thakur, Bhushan L., Pongor, Lőrinc S., Baris, Adrian M., Gross, Jacob M., OʹNeill, Maura J., Indig, Fred E., Cappell, Steven D., Aladjem, Mirit I.
Publicado 2020

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells

por Zhang, Ya, Huang, Liang, Fu, Haiqing, Smith, Owen K., Lin, Chii Mei, Utani, Koichi, Rao, Mishal, Reinhold, William C., Redon, Christophe E., Ryan, Michael, Kim, RyangGuk, You, Yang, Hanna, Harlington, Boisclair, Yves, Long, Qiaoming, Aladjem, Mirit I.
Publicado 2016