Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs—First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor

por Lingappa, Jaisri R., Lingappa, Vishwanath R., Reed, Jonathan C.
Publicado 2021

Host ABCE1 is at Plasma Membrane HIV Assembly Sites and Its Dissociation from Gag is Linked to Subsequent Events of Virus Production

por Dooher, Julia E, Schneider, Bobbie L, Reed, Jonathan C, Lingappa, Jaisri R
Publicado 2007

Mutations of Conserved Residues in the Major Homology Region Arrest Assembling HIV-1 Gag as a Membrane-Targeted Intermediate Containing Genomic RNA and Cellular Proteins

por Tanaka, Motoko, Robinson, Bridget A., Chutiraka, Kasana, Geary, Clair D., Reed, Jonathan C., Lingappa, Jaisri R.
Publicado 2016

Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging

por Barajas, Brook C., Tanaka, Motoko, Robinson, Bridget A., Phuong, Daryl J., Chutiraka, Kasana, Reed, Jonathan C., Lingappa, Jaisri R.
Publicado 2018

HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly

por Reed, Jonathan C., Molter, Britta, Geary, Clair D., McNevin, John, McElrath, Julie, Giri, Samina, Klein, Kevin C., Lingappa, Jaisri R.
Publicado 2012

A SARS-CoV-2 Nucleocapsid Variant that Affects Antigen Test Performance

por Bourassa, Lori, Perchetti, Garrett A., Phung, Quynh, Lin, Michelle J., Mills, Margaret G., Roychoudhury, Pavitra, Harmon, Kimberly G., Reed, Jonathan C., Greninger, Alexander L.
Publicado 2021

Identification of an Antiretroviral Small Molecule That Appears To Be a Host-Targeting Inhibitor of HIV-1 Assembly

por Reed, Jonathan C., Solas, Dennis, Kitaygorodskyy, Anatoliy, Freeman, Beverly, Ressler, Dylan T. B., Phuong, Daryl J., Swain, J. Victor, Matlack, Kent, Hurt, Clarence R., Lingappa, Vishwanath R., Lingappa, Jaisri R.
Publicado 2021