Advancing Personalized Medicine in Common Forms of Parkinson’s Disease through Genetics: Current Therapeutics and the Future of Individualized Management

por Reed, Xylena, Schumacher-Schuh, Artur, Hu, Jing, Bandres-Ciga, Sara
Publicado 2021

Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2)

por Beylina, Aleksandra, Langston, Rebekah G., Rosen, Dorien, Reed, Xylena, Cookson, Mark R.
Publicado 2021

Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1

por Chen, Steven C., Frett, Ellie, Marx, Joseph, Bosnakovski, Darko, Reed, Xylena, Kyba, Michael, Kennedy, Brian K.
Publicado 2011

Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control

por Burzynski, Grzegorz M., Reed, Xylena, Taher, Leila, Stine, Zachary E., Matsui, Takeshi, Ovcharenko, Ivan, McCallion, Andrew S.
Publicado 2012

Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched

por Reed, Xylena, Cobb, Melanie M., Skinbinski, Gaia, Roosen, Dorien, Kaganovich, Alice, Ding, Jinhui, Finkbeiner, Steve, Cookson, Mark R.
Publicado 2021

Human brain single nucleus cell type enrichments in neurodegenerative diseases

por Alvarado, Chelsea X, Weller, Cory A., Johnson, Nicholas, Leonard, Hampton L., Singleton, Andrew B., Reed, Xylena, Blauewendraat, Cornelis, Nalls, Mike A
Publicado 2023

Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk

por Lake, Julie, Reed, Xylena, Langston, Rebekah G., Nalls, Mike A., Gan‐Or, Ziv, Cookson, Mark R., Singleton, Andrew B., Blauwendraat, Cornelis, Leonard, Hampton L.
Publicado 2021

Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes

por Gorkin, David U., Lee, Dongwon, Reed, Xylena, Fletez-Brant, Christopher, Bessling, Seneca L., Loftus, Stacie K., Beer, Michael A., Pavan, William J., McCallion, Andrew S.
Publicado 2012

SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer

por Prasad, Megana K, Reed, Xylena, Gorkin, David U, Cronin, Julia C, McAdow, Anthony R, Chain, Kristopher, Hodonsky, Chani J, Jones, Erin A, Svaren, John, Antonellis, Anthony, Johnson, Stephen L, Loftus, Stacie K, Pavan, William J, McCallion, Andrew S
Publicado 2011

An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome

por Snyder, Allison, Ryan, Veronica H, Hawrot, James, Lawton, Sydney, Ramos, Daniel M, Qi, Y Andy, Johnson, Kory, Reed, Xylena, Johnson, Nicholas L, Kollasch, Aaron W, Duffy, Megan, VandeVrede, Lawren, Cochran, J Nicholas, Miller, Bruce L, Toro, Camilo, Bielekova, Bibiana, Yokoyama, Jennifer S, Marks, Debora S, Kwan, Justin Y, Cookson, Mark R, Ward, Michael E
Publicado 2023

The Parkinson's Disease Genome‐Wide Association Study Locus Browser

por Grenn, Francis P., Kim, Jonggeol J., Makarious, Mary B., Iwaki, Hirotaka, Illarionova, Anastasia, Brolin, Kajsa, Kluss, Jillian H., Schumacher‐Schuh, Artur F., Leonard, Hampton, Faghri, Faraz, Billingsley, Kimberley, Krohn, Lynne, Hall, Ashley, Diez‐Fairen, Monica, Periñán, Maria Teresa, Foo, Jia Nee, Sandor, Cynthia, Webber, Caleb, Fiske, Brian K., Gibbs, J. Raphael, Nalls, Mike A., Singleton, Andrew B., Bandres‐Ciga, Sara, Reed, Xylena, Blauwendraat, Cornelis
Publicado 2020

Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation

por Kolmogorov, Mikhail, Billingsley, Kimberley J., Mastoras, Mira, Meredith, Melissa, Monlong, Jean, Lorig-Roach, Ryan, Asri, Mobin, Jerez, Pilar Alvarez, Malik, Laksh, Dewan, Ramita, Reed, Xylena, Genner, Rylee M., Daida, Kensuke, Behera, Sairam, Shafin, Kishwar, Pesout, Trevor, Prabakaran, Jeshuwin, Carnevali, Paolo, Yang, Jianzhi, Rhie, Arang, Scholz, Sonja W., Traynor, Bryan J., Miga, Karen H., Jain, Miten, Timp, Winston, Phillippy, Adam M., Chaisson, Mark, Sedlazeck, Fritz J., Blauwendraat, Cornelis, Paten, Benedict
Publicado 2023

The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism

por Bressan, Elisangela, Reed, Xylena, Bansal, Vikas, Hutchins, Elizabeth, Cobb, Melanie M., Webb, Michelle G., Alsop, Eric, Grenn, Francis P., Illarionova, Anastasia, Savytska, Natalia, Violich, Ivo, Broeer, Stefanie, Fernandes, Noémia, Sivakumar, Ramiyapriya, Beilina, Alexandra, Billingsley, Kimberley J., Berghausen, Joos, Pantazis, Caroline B., Pitz, Vanessa, Patel, Dhairya, Daida, Kensuke, Meechoovet, Bessie, Reiman, Rebecca, Courtright-Lim, Amanda, Logemann, Amber, Antone, Jerry, Barch, Mariya, Kitchen, Robert, Li, Yan, Dalgard, Clifton L., Rizzu, Patrizia, Hernandez, Dena G., Hjelm, Brooke E., Nalls, Mike, Gibbs, J. Raphael, Finkbeiner, Steven, Cookson, Mark R., Van Keuren-Jensen, Kendall, Craig, David W., Singleton, Andrew B., Heutink, Peter, Blauwendraat, Cornelis
Publicado 2023