Blocking type TSH receptor antibodies

por Furmaniak, Jadwiga, Sanders, Jane, Rees Smith, Bernard
Publicado 2012

TSH receptor specific monoclonal autoantibody K1‐70(TM) targeting of the TSH receptor in subjects with Graves' disease and Graves' orbitopathy—Results from a phase I clinical trial...

por Furmaniak, Jadwiga, Sanders, Jane, Sanders, Paul, Li, Yang, Rees Smith, Bernard
Publicado 2022

Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70(TM) a human monoclonal autoantibody to the TSH receptor with TSH antagonist activity

por Furmaniak, Jadwiga, Sanders, Jane, Clark, Jill, Wilmot, Jane, Sanders, Paul, Li, Yang, Rees Smith, Bernard
Publicado 2019

Characteristic phenotype of Chinese patients with adult-onset diabetes who are autoantibody positive by 3-Screen ICA™ ELISA

por Wang, Zhida, Guo, Liang, Chen, Shu, Guan, Jun, Powell, Michael, Furmaniak, Jadwiga, Rees Smith, Bernard, Chen, Liming
Publicado 2021

In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)

por Furmaniak, Jadwiga, Sanders, Jane, Young, Stuart, Kabelis, Katarzyna, Sanders, Paul, Evans, Michele, Clark, Jill, Wilmot, Jane, Rees Smith, Bernard
Publicado 2011

Structure of full-length TSH receptor in complex with antibody K1-70™

por Núñez Miguel, Ricardo, Sanders, Paul, Allen, Lloyd, Evans, Michele, Holly, Matthew, Johnson, William, Sullivan, Andrew, Sanders, Jane, Furmaniak, Jadwiga, Rees Smith, Bernard
Publicado 2022

The prevalence of diabetes and thyroid related autoantibodies in Sri Lankan children with type 1 diabetes and their unaffected siblings – The utility of a new screening assay

por Atapattu, Navoda, Amoroso, Marie, Powell, Michael, de Silva, D. G. Harendra, de Silva, K. Shamya H., Furmaniak, Jadwiga, Rees Smith, Bernard, Premawardhana, Lakdasa D.
Publicado 2023