Making Enzymes Suitable for Organic Chemistry by Rational Protein Design

por Reetz, Manfred
Publicado 2022

Mixtures of monodentate P-ligands as a means to control the diastereoselectivity in Rh-catalyzed hydrogenation of chiral alkenes

por Reetz, Manfred T, Guo, Hongchao
Publicado 2005

The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions

por Reetz, Manfred T., Garcia-Borràs, Marc
Publicado 2021

Crystal structure of 7,8,9,10-tetra­hydro­benzo[b]naphtho­[2,1-d]furan

por Wu, Zhongyuan, Reetz, Manfred T., Harms, Klaus
Publicado 2016

Exploiting Designed Oxidase–Peroxygenase Mutual Benefit System for Asymmetric Cascade Reactions

por Yu, Da, Wang, Jian-bo, Reetz, Manfred T.
Publicado 2019

Towards practical biocatalytic Baeyer-Villiger reactions: applying a thermostable enzyme in the gram-scale synthesis of optically-active lactones in a two-liquid-phase system

por Schulz, Frank, Leca, François, Hollmann, Frank, Reetz, Manfred T
Publicado 2005

Economical analysis of saturation mutagenesis experiments

por Acevedo-Rocha, Carlos G., Reetz, Manfred T., Nov, Yuval
Publicado 2015

Boosting the efficiency of site-saturation mutagenesis for a difficult-to-randomize gene by a two-step PCR strategy

por Li, Aitao, Acevedo-Rocha, Carlos G., Reetz, Manfred T.
Publicado 2018

Chemical and Biocatalytic Routes to Arbutin †

por Zhou, Hangyu, Zhao, Jing, Li, Aitao, Reetz, Manfred T.
Publicado 2019

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

por Cen, Yixin, Singh, Warispreet, Arkin, Mamatjan, Moody, Thomas S., Huang, Meilan, Zhou, Jiahai, Wu, Qi, Reetz, Manfred T.
Publicado 2019

P450-BM3-Catalyzed Sulfoxidation versus Hydroxylation: A Common or Two Different Catalytically Active Species?

por Wang, Jian-bo, Huang, Qun, Peng, Wei, Wu, Peng, Yu, Da, Chen, Bo, Wang, Binju, Reetz, Manfred T.
Publicado 2020

A redox-mediated Kemp eliminase

por Li, Aitao, Wang, Binju, Ilie, Adriana, Dubey, Kshatresh D., Bange, Gert, Korendovych, Ivan V., Shaik, Sason, Reetz, Manfred T.
Publicado 2017

Correction: Simultaneous engineering of an enzyme’s entrance tunnel and active site: the case of monoamine oxidase MAO-N

por Li, Guangyue, Yao, Peiyuan, Gong, Rui, Li, Jinlong, Liu, Pi, Lonsdale, Richard, Wu, Qiaqing, Lin, Jianping, Zhu, Dunming, Reetz, Manfred T.
Publicado 2017

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N

por Li, Guangyue, Yao, Peiyuan, Gong, Rui, Li, Jinlong, Liu, Pi, Lonsdale, Richard, Wu, Qiaqing, Lin, Jianping, Zhu, Dunming, Reetz, Manfred T.
Publicado 2017

A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

por Cadet, Frédéric, Fontaine, Nicolas, Li, Guangyue, Sanchis, Joaquin, Ng Fuk Chong, Matthieu, Pandjaitan, Rudy, Vetrivel, Iyanar, Offmann, Bernard, Reetz, Manfred T.
Publicado 2018

Publisher Correction: A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

por Cadet, Frédéric, Fontaine, Nicolas, Li, Guangyue, Sanchis, Joaquin, Chong, Matthieu Ng Fuk, Pandjaitan, Rudy, Vetrivel, Iyanar, Offmann, Bernard, Reetz, Manfred T.
Publicado 2021

Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles

por Li, Jun-Kuan, Qu, Ge, Li, Xu, Tian, Yuchen, Cui, Chengsen, Zhang, Fa-Guang, Zhang, Wuyuan, Ma, Jun-An, Reetz, Manfred T., Sun, Zhoutong
Publicado 2022

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

por Acevedo-Rocha, Carlos G., Li, Aitao, D’Amore, Lorenzo, Hoebenreich, Sabrina, Sanchis, Joaquin, Lubrano, Paul, Ferla, Matteo P., Garcia-Borràs, Marc, Osuna, Sílvia, Reetz, Manfred T.
Publicado 2021

Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants

por Li, Aitao, Acevedo‐Rocha, Carlos G., D'Amore, Lorenzo, Chen, Jinfeng, Peng, Yaqin, Garcia‐Borràs, Marc, Gao, Chenghua, Zhu, Jinmei, Rickerby, Harry, Osuna, Sílvia, Zhou, Jiahai, Reetz, Manfred T.
Publicado 2020

Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation

por Li, Guangyue, Qin, Youcai, Fontaine, Nicolas T., Ng Fuk Chong, Matthieu, Maria‐Solano, Miguel A., Feixas, Ferran, Cadet, Xavier F., Pandjaitan, Rudy, Garcia‐Borràs, Marc, Cadet, Frederic, Reetz, Manfred T.
Publicado 2020