Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?()

por Reeve, Amy, Simcox, Eve, Turnbull, Doug
Publicado 2014

Mitochondrial Dysfunction in Parkinson’s Disease—Cause or Consequence?

por Chen, Chun, Turnbull, Doug M., Reeve, Amy K.
Publicado 2019

Mitochondrial Mutations: Newly Discovered Players in Neuronal Degeneration

por Lax, Nichola Z., Turnbull, Doug M., Reeve, Amy K.
Publicado 2011

The ageing mitochondrial genome

por Krishnan, Kim J., Greaves, Laura C., Reeve, Amy K., Turnbull, Doug
Publicado 2007

The rise and rise of mitochondrial DNA mutations

por Lawless, Conor, Greaves, Laura, Reeve, Amy K., Turnbull, Doug M., Vincent, Amy E.
Publicado 2020

No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis

por Campbell, Graham R, Reeve, Amy K, Ziabreva, Iryna, Reynolds, Richard, Turnbull, Doug M, Mahad, Don J
Publicado 2013

Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease

por Reeve, Amy K., Grady, John P., Cosgrave, Eve M., Bennison, Emma, Chen, Chun, Hepplewhite, Philippa D., Morris, Christopher M.
Publicado 2018

The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons

por Reeve, Amy K, Krishnan, Kim J, Taylor, Geoffrey, Elson, Joanna L, Bender, Andreas, Taylor, Robert W, Morris, Christopher M, Turnbull, Doug M
Publicado 2009

Microangiopathy in the cerebellum of patients with mitochondrial DNA disease

por Lax, Nichola Z., Pienaar, Ilse S., Reeve, Amy K., Hepplewhite, Philippa D., Jaros, Evelyn, Taylor, Robert W., Kalaria, Raj N., Turnbull, Doug M.
Publicado 2012

OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules

por Yu-Wai-Man, Patrick, Sitarz, Kamil S., Samuels, David C., Griffiths, Philip G., Reeve, Amy K., Bindoff, Laurence A., Horvath, Rita, Chinnery, Patrick F.
Publicado 2010

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

por Campbell, Graham R, Ziabreva, Iryna, Reeve, Amy K, Krishnan, Kim J, Reynolds, Richard, Howell, Owen, Lassmann, Hans, Turnbull, Doug M, Mahad, Don J
Publicado 2011

Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue

por Grünewald, Anne, Lax, Nichola Z., Rocha, Mariana C., Reeve, Amy K., Hepplewhite, Philippa D., A. Rygiel, Karolina, Taylor, Robert W., Turnbull, Doug M.
Publicado 2014

3D neuronal mitochondrial morphology in axons, dendrites, and somata of the aging mouse hippocampus

por Faitg, Julie, Lacefield, Clay, Davey, Tracey, White, Kathryn, Laws, Ross, Kosmidis, Stylianos, Reeve, Amy K., Kandel, Eric R., Vincent, Amy E., Picard, Martin
Publicado 2021

Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies

por Hatton, Christopher, Reeve, Amy, Lax, Nichola Zoe, Blain, Alasdair, Ng, Yi Shiau, El-Agnaf, Omar, Attems, Johannes, Taylor, John-Paul, Turnbull, Doug, Erskine, Daniel
Publicado 2020

Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis

por Rygiel, Karolina A., Tuppen, Helen A., Grady, John P., Vincent, Amy, Blakely, Emma L., Reeve, Amy K., Taylor, Robert W., Picard, Martin, Miller, James, Turnbull, Doug M.
Publicado 2016

Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss

por Dobson, Philip F., Dennis, Ella P., Hipps, Daniel, Reeve, Amy, Laude, Alex, Bradshaw, Carla, Stamp, Craig, Smith, Anna, Deehan, David J., Turnbull, Doug M., Greaves, Laura C.
Publicado 2020

Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls

por Erskine, Daniel, Reeve, Amy K., Polvikoski, Tuomo, Schaefer, Andrew M., Taylor, Robert W., Lax, Nichola Z., El-Agnaf, Omar, Attems, Johannes, Gorman, Gráinne S., Turnbull, Doug M., Ng, Yi Shau
Publicado 2019

Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein

por Tweedy, Clare, Kindred, Nathan, Curry, Joshua, Williams, Christopher, Taylor, John-Paul, Atkinson, Peter, Randall, Fiona, Erskine, Daniel, Morris, Christopheer M., Reeve, Amy K., Clowry, Gavin J., LeBeau, Fiona E.N.
Publicado 2021

Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease

por Chen, Chun, McDonald, David, Blain, Alasdair, Sachdeva, Ashwin, Bone, Laura, Smith, Anna L. M., Warren, Charlotte, Pickett, Sarah J., Hudson, Gavin, Filby, Andrew, Vincent, Amy E., Turnbull, Doug M., Reeve, Amy K.
Publicado 2021

Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins

por Chen, Chun, McDonald, David, Blain, Alasdair, Mossman, Emily, Atkin, Kiera, Marusich, Michael F., Capaldi, Roderick, Bone, Laura, Smith, Anna, Filby, Andrew, Erskine, Daniel, Russell, Oliver, Hudson, Gavin, Vincent, Amy E., Reeve, Amy K.
Publicado 2023