Data management strategies for multinational large-scale systems biology projects

por Wruck, Wasco, Peuker, Martin, Regenbrecht, Christian R.A.
Publicado 2014

From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity

por Gambara, Guido, Gaebler, Manuela, Keilholz, Ulrich, Regenbrecht, Christian R. A., Silvestri, Alessandra
Publicado 2018

Context Matters—Why We Need to Change From a One Size Fits all Approach to Made-to-Measure Therapies for Individual Patients With Pancreatic Cancer

por Sankarasubramanian, Sushmitha, Pfohl, Ulrike, Regenbrecht, Christian R. A., Reinhard, Christoph, Wedeken, Lena
Publicado 2021

Precision Oncology Beyond Genomics: The Future Is Here—It Is Just Not Evenly Distributed

por Pfohl, Ulrike, Pflaume, Alina, Regenbrecht, Manuela, Finkler, Sabine, Graf Adelmann, Quirin, Reinhard, Christoph, Regenbrecht, Christian R. A., Wedeken, Lena
Publicado 2021

Three-Dimensional Patient-Derived In Vitro Sarcoma Models: Promising Tools for Improving Clinical Tumor Management

por Gaebler, Manuela, Silvestri, Alessandra, Haybaeck, Johannes, Reichardt, Peter, Lowery, Caitlin D., Stancato, Louis F., Zybarth, Gabriele, Regenbrecht, Christian R. A.
Publicado 2017

The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma Cells

por Redmer, Torben, Welte, Yvonne, Behrens, Diana, Fichtner, Iduna, Przybilla, Dorothea, Wruck, Wasco, Yaspo, Marie-Laure, Lehrach, Hans, Schäfer, Reinhold, Regenbrecht, Christian R. A.
Publicado 2014

Glioblastoma cells express functional cell membrane receptors activated by daily used medical drugs

por Kuhn, Susanne A., Mueller, Ulrike, Hanisch, Uwe-K., Regenbrecht, Christian R. A., Schoenwald, Ilona, Brodhun, Michael, Kosmehl, Hartwig, Ewald, Christian, Kalff, Rolf, Reichart, Rupert
Publicado 2009

Photon and Proton irradiation in Patient-derived, Three-Dimensional Soft Tissue Sarcoma Models

por Roohani, Siyer, Loskutov, Jürgen, Heufelder, Jens, Ehret, Felix, Wedeken, Lena, Regenbrecht, Manuela, Sauer, Rica, Zips, Daniel, Denker, Andrea, Joussen, Antonia M., Regenbrecht, Christian R. A., Kaul, David
Publicado 2023

A RAS-Independent Biomarker Panel to Reliably Predict Response to MEK Inhibition in Colorectal Cancer

por Pfohl, Ulrike, Loskutov, Jürgen, Bashir, Sanum, Kühn, Ralf, Herter, Patrick, Templin, Markus, Mamlouk, Soulafa, Belanov, Sergei, Linnebacher, Michael, Bürtin, Florian, Vetter, Marcus, Reinhard, Christoph, Wedeken, Lena, Regenbrecht, Christian R. A.
Publicado 2022

Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures

por Boehnke, Karsten, Iversen, Philip W., Schumacher, Dirk, Lallena, María José, Haro, Rubén, Amat, Joaquín, Haybaeck, Johannes, Liebs, Sandra, Lange, Martin, Schäfer, Reinhold, Regenbrecht, Christian R. A., Reinhard, Christoph, Velasco, Juan A.
Publicado 2016

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures

por Schumacher, Dirk, Andrieux, Geoffroy, Boehnke, Karsten, Keil, Marlen, Silvestri, Alessandra, Silvestrov, Maxine, Keilholz, Ulrich, Haybaeck, Johannes, Erdmann, Gerrit, Sachse, Christoph, Templin, Markus, Hoffmann, Jens, Boerries, Melanie, Schäfer, Reinhold, Regenbrecht, Christian R. A.
Publicado 2019

RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence

por Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Publicado 2021

Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis

por Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Publicado 2022

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

por Schütte, Moritz, Risch, Thomas, Abdavi-Azar, Nilofar, Boehnke, Karsten, Schumacher, Dirk, Keil, Marlen, Yildiriman, Reha, Jandrasits, Christine, Borodina, Tatiana, Amstislavskiy, Vyacheslav, Worth, Catherine L., Schweiger, Caroline, Liebs, Sandra, Lange, Martin, Warnatz, Hans- Jörg, Butcher, Lee M., Barrett, James E., Sultan, Marc, Wierling, Christoph, Golob-Schwarzl, Nicole, Lax, Sigurd, Uranitsch, Stefan, Becker, Michael, Welte, Yvonne, Regan, Joseph Lewis, Silvestrov, Maxine, Kehler, Inge, Fusi, Alberto, Kessler, Thomas, Herwig, Ralf, Landegren, Ulf, Wienke, Dirk, Nilsson, Mats, Velasco, Juan A., Garin-Chesa, Pilar, Reinhard, Christoph, Beck, Stephan, Schäfer, Reinhold, Regenbrecht, Christian R. A., Henderson, David, Lange, Bodo, Haybaeck, Johannes, Keilholz, Ulrich, Hoffmann, Jens, Lehrach, Hans, Yaspo, Marie-Laure
Publicado 2017