Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection

por Reginato, Giordano, Cannavo, Elda, Cejka, Petr
Publicado 2017

Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners

por Marsella, Antonio, Gobbini, Elisa, Cassani, Corinne, Tisi, Renata, Cannavo, Elda, Reginato, Giordano, Cejka, Petr, Longhese, Maria Pia
Publicado 2021

Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres

por Spegg, Vincent, Panagopoulos, Andreas, Stout, Merula, Krishnan, Aswini, Reginato, Giordano, Imhof, Ralph, Roschitzki, Bernd, Cejka, Petr, Altmeyer, Matthias
Publicado 2023

A highly specific SpCas9 variant is identified by in vivo screening in yeast

por Casini, Antonio, Olivieri, Michele, Petris, Gianluca, Montagna, Claudia, Reginato, Giordano, Maule, Giulia, Lorenzin, Francesca, Prandi, Davide, Romanel, Alessandro, Demichelis, Francesca, Inga, Alberto, Cereseto, Anna
Publicado 2018

The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length

por Vernekar, Dipti Vinayak, Reginato, Giordano, Adam, Céline, Ranjha, Lepakshi, Dingli, Florent, Marsolier, Marie-Claude, Loew, Damarys, Guérois, Raphaël, Llorente, Bertrand, Cejka, Petr, Borde, Valérie
Publicado 2021

Mre11-Rad50 oligomerization promotes DNA double-strand break repair

por Kissling, Vera M., Reginato, Giordano, Bianco, Eliana, Kasaciunaite, Kristina, Tilma, Janny, Cereghetti, Gea, Schindler, Natalie, Lee, Sung Sik, Guérois, Raphaël, Luke, Brian, Seidel, Ralf, Cejka, Petr, Peter, Matthias
Publicado 2022