The use of CrossMAb technology for the generation of bi- and multispecific antibodies

por Klein, Christian, Schaefer, Wolfgang, Regula, Jörg T.
Publicado 2016

Proteomic screen in the simple metazoan Hydra identifies 14-3-3 binding proteins implicated in cellular metabolism, cytoskeletal organisation and Ca(2+ )signalling

por Pauly, Barbara, Lasi, Margherita, MacKintosh, Carol, Morrice, Nick, Imhof, Axel, Regula, Jörg, Rudd, Stephen, David, Charles N, Böttger, Angelika
Publicado 2007

Low Level Sequence Variant Analysis of Recombinant Proteins: An Optimized Approach

por Zeck, Anne, Regula, Jörg Thomas, Larraillet, Vincent, Mautz, Björn, Popp, Oliver, Göpfert, Ulrich, Wiegeshoff, Frank, Vollertsen, Ulrike E. E., Gorr, Ingo H., Koll, Hans, Papadimitriou, Apollon
Publicado 2012

Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2

por Scheuer, Werner, Thomas, Markus, Hanke, Petra, Sam, Johannes, Osl, Franz, Weininger, Diana, Baehner, Monika, Seeber, Stefan, Kettenberger, Hubert, Schanzer, Jürgen, Brinkmann, Ulrich, Weidner, K. Michael, Regula, Jörg, Klein, Christian
Publicado 2016

A Novel Angiopoietin-2 Selective Fully Human Antibody with Potent Anti-Tumoral and Anti-Angiogenic Efficacy and Superior Side Effect Profile Compared to Pan-Angiopoietin-1/-2 Inhib...

por Thomas, Markus, Kienast, Yvonne, Scheuer, Werner, Bähner, Monika, Kaluza, Klaus, Gassner, Christian, Herting, Frank, Brinkmann, Ulrich, Seeber, Stefan, Kavlie, Anita, Welschof, Martin, Ries, Stefan, Weidner, K. Michael, Regula, Jörg T., Klein, Christian
Publicado 2013

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases

por Regula, Jörg T, Lundh von Leithner, Peter, Foxton, Richard, Barathi, Veluchamy A, Cheung, Chui Ming Gemmy, Bo Tun, Sai Bo, Wey, Yeo Sia, Iwata, Daiju, Dostalek, Miroslav, Moelleken, Jörg, Stubenrauch, Kay G, Nogoceke, Everson, Widmer, Gabriella, Strassburger, Pamela, Koss, Michael J, Klein, Christian, Shima, David T, Hartmann, Guido
Publicado 2016

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

por Sustmann, Claudio, Dickopf, Steffen, Regula, Jörg T., Kettenberger, Hubert, Mølhøj, Michael, Gassner, Christian, Weininger, Diana, Fenn, Sebastian, Manigold, Tobias, Kling, Lothar, Künkele, Klaus-Peter, Schwaiger, Manfred, Bossenmaier, Birgit, Griese, Julia J., Hopfner, Karl-Peter, Graff-Meyer, Alexandra, Stahlberg, Henning, Ringler, Philippe, Lauer, Matthias E., Brinkmann, Ulrich, Schaefer, Wolfgang, Klein, Christian
Publicado 2019