Epac-Inhibitors: Facts and Artefacts

por Rehmann, Holger
Publicado 2013

A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

por Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger
Publicado 2019

Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish

por Smith, Kelly A., Noël, Emily, Thurlings, Ingrid, Rehmann, Holger, Chocron, Sonja, Bakkers, Jeroen
Publicado 2011

Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance

por Pannekoek, Willem-Jan, Linnemann, Jelena R., Brouwer, Patricia M., Bos, Johannes L., Rehmann, Holger
Publicado 2013

The Rap1 Guanine Nucleotide Exchange Factor C3G Is Required for Preservation of Larval Muscle Integrity in Drosophila melanogaster

por Shirinian, Margret, Grabbe, Caroline, Popovic, Milica, Varshney, Gaurav, Hugosson, Fredrik, Bos, Hans, Rehmann, Holger, Palmer, Ruth H.
Publicado 2010

Correction: The Rap1 Guanine Nucleotide Exchange Factor C3G Is Required for Preservation of Larval Muscle Integrity in Drosophila melanogaster

por Shirinian, Margret, Popovic, Milica, Grabbe, Caroline, Varshney, Gaurav, Hugosson, Fredrik, Bos, Hans, Rehmann, Holger, Palmer, Ruth H.
Publicado 2010

A Receptor-associated Protein/Phosphatidylinositol 3-Kinase Pathway Controls Pseudopod Formation

por Kortholt, Arjan, Bolourani, Parvin, Rehmann, Holger, Keizer-Gunnink, Ineke, Weeks, Gerald, Wittinghofer, Alfred, Van Haastert, Peter J.M.
Publicado 2010

Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22

por Woller, Barbara, Luiskandl, Susan, Popovic, Milica, Prieler, Barbara E.M., Ikonge, Gloria, Mutzl, Michaela, Rehmann, Holger, Herbst, Ruth
Publicado 2011

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity

por Gloerich, Martijn, Vliem, Marjolein J., Prummel, Esther, Meijer, Lars A.T., Rensen, Marije G.A., Rehmann, Holger, Bos, Johannes L.
Publicado 2011

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

por Huveneers, Stephan, Oldenburg, Joppe, Spanjaard, Emma, van der Krogt, Gerard, Grigoriev, Ilya, Akhmanova, Anna, Rehmann, Holger, de Rooij, Johan
Publicado 2012

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1

por Parnell, Euan, McElroy, Stuart P., Wiejak, Jolanta, Baillie, Gemma L., Porter, Alison, Adams, David R., Rehmann, Holger, Smith, Brian O., Yarwood, Stephen J.
Publicado 2017

Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects

por Runtuwene, Vincent, van Eekelen, Mark, Overvoorde, John, Rehmann, Holger, Yntema, Helger G., Nillesen, Willy M., van Haeringen, Arie, van der Burgt, Ineke, Burgering, Boudewijn, den Hertog, Jeroen
Publicado 2011

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation

por Twiss, Floor, Le Duc, Quint, Van Der Horst, Suzanne, Tabdili, Hamid, Van Der Krogt, Gerard, Wang, Ning, Rehmann, Holger, Huveneers, Stephan, Leckband, Deborah E., De Rooij, Johan
Publicado 2012

Functional characterisation of a novel class of in-frame insertion variants of KRAS and HRAS

por Eijkelenboom, Astrid, van Schaik, Frederik M. A., van Es, Robert M., Ten Broek, Roel W., Rinne, Tuula, van der Vleuten, Carine, Flucke, Uta, Ligtenberg, Marjolijn J. L., Rehmann, Holger
Publicado 2019

NAA80 bi-allelic missense variants result in high-frequency hearing loss, muscle weakness and developmental delay

por Muffels, Irena J J, Wiame, Elsa, Fuchs, Sabine A, Massink, Maarten P G, Rehmann, Holger, Musch, Jiska L I, Van Haaften, Gijs, Vertommen, Didier, van Schaftingen, Emile, van Hasselt, Peter M
Publicado 2021

A second case of glutaminase hyperactivity: Expanding the phenotype with epilepsy

por Rumping, Lynne, Pouwels, Petra J. W., Wolf, Nicole I., Rehmann, Holger, Wamelink, Mirjam M. C., Waisfisz, Quinten, Jans, Judith J. M., Prinsen, Hubertus C. M. T., van de Kamp, Jiddeke M., van Hasselt, Peter M.
Publicado 2023

Structure-Guided Design of Selective Epac1 and Epac2 Agonists

por Schwede, Frank, Bertinetti, Daniela, Langerijs, Carianne N., Hadders, Michael A., Wienk, Hans, Ellenbroek, Johanne H., de Koning, Eelco J. P., Bos, Johannes L., Herberg, Friedrich W., Genieser, Hans-Gottfried, Janssen, Richard A. J., Rehmann, Holger
Publicado 2015

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

por Park, Sung-Jun, Ahmad, Faiyaz, Philp, Andrew, Baar, Keith, Williams, Tishan, Luo, Haibin, Ke, Hengming, Rehmann, Holger, Taussig, Ronald, Brown, Alexandra L, Kim, Myung K, Beaven, Michael A, Burgin, Alex B, Manganiello, Vincent, Chung, Jay H
Publicado 2012

Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes

por Hoogenraad, Casper C., Popa, Ioana, Futai, Kensuke, Sanchez-Martinez, Emma, Wulf, Phebe S., van Vlijmen, Thijs, Dortland, Bjorn R., Oorschot, Viola, Govers, Roland, Monti, Maria, Heck, Albert J. R., Sheng, Morgan, Klumperman, Judith, Rehmann, Holger, Jaarsma, Dick, Kapitein, Lukas C., van der Sluijs, Peter
Publicado 2010

Correction: Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes

por Hoogenraad, Casper C., Popa, Ioana, Futai, Kensuke, Martinez-Sanchez, Emma, Wulf, Phebe S., van Vlijmen, Thijs, Dortland, Bjorn R., Oorschot, Viola, Govers, Roland, Monti, Maria, Heck, Albert J. R., Sheng, Morgan, Klumperman, Judith, Rehmann, Holger, Jaarsma, Dick, Kapitein, Lukas C., van der Sluijs, Peter
Publicado 2010