Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model

por Joshi, Lisha, Plastira, Ioanna, Bernhart, Eva, Reicher, Helga, Triebl, Alexander, Köfeler, Harald C., Sattler, Wolfgang
Publicado 2021

Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro

por Üllen, Andreas, Fauler, Günter, Bernhart, Eva, Nusshold, Christoph, Reicher, Helga, Leis, Hans-Jörg, Malle, Ernst, Sattler, Wolfgang
Publicado 2012

MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia

por Plastira, Ioanna, Bernhart, Eva, Joshi, Lisha, Koyani, Chintan N., Strohmaier, Heimo, Reicher, Helga, Malle, Ernst, Sattler, Wolfgang
Publicado 2020

Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons()

por Nusshold, Christoph, Uellen, Andreas, Bernhart, Eva, Hammer, Astrid, Damm, Sabine, Wintersperger, Andrea, Reicher, Helga, Hermetter, Albin, Malle, Ernst, Sattler, Wolfgang
Publicado 2013

Lysophosphatidic Acid Receptor 5 (LPA(5)) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In...

por Joshi, Lisha, Plastira, Ioanna, Bernhart, Eva, Reicher, Helga, Koshenov, Zhanat, Graier, Wolfgang F., Vujic, Nemanja, Kratky, Dagmar, Rivera, Richard, Chun, Jerold, Sattler, Wolfgang
Publicado 2022

Myeloperoxidase-Derived Oxidants Induce Blood-Brain Barrier Dysfunction In Vitro and In Vivo

por Üllen, Andreas, Singewald, Evelin, Konya, Viktoria, Fauler, Günter, Reicher, Helga, Nusshold, Christoph, Hammer, Astrid, Kratky, Dagmar, Heinemann, Akos, Holzer, Peter, Malle, Ernst, Sattler, Wolfgang
Publicado 2013

Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells

por Bernhart, Eva, Damm, Sabine, Wintersperger, Andrea, Nusshold, Christoph, Brunner, Anna Martina, Plastira, Ioanna, Rechberger, Gerald, Reicher, Helga, Wadsack, Christian, Zimmer, Andreas, Malle, Ernst, Sattler, Wolfgang
Publicado 2015

Lysophosphatidic Acid Induces Aerobic Glycolysis, Lipogenesis, and Increased Amino Acid Uptake in BV-2 Microglia

por Joshi, Lisha, Plastira, Ioanna, Bernhart, Eva, Reicher, Helga, Koyani, Chintan N., Madl, Tobias, Madreiter-Sokolowski, Corina, Koshenov, Zhanat, Graier, Wolfgang F., Hallström, Seth, Sattler, Wolfgang
Publicado 2021

Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages

por Schlager, Stefanie, Vujic, Nemanja, Korbelius, Melanie, Duta-Mare, Madalina, Dorow, Juliane, Leopold, Christina, Rainer, Silvia, Wegscheider, Martin, Reicher, Helga, Ceglarek, Uta, Sattler, Wolfgang, Radovic, Branislav, Kratky, Dagmar
Publicado 2017

Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro

por Prasch, Jürgen, Bernhart, Eva, Reicher, Helga, Kollroser, Manfred, Rechberger, Gerald N., Koyani, Chintan N., Trummer, Christopher, Rech, Lavinia, Rainer, Peter P., Hammer, Astrid, Malle, Ernst, Sattler, Wolfgang
Publicado 2020

1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype

por Plastira, Ioanna, Bernhart, Eva, Goeritzer, Madeleine, Reicher, Helga, Kumble, Vishwanath Bhat, Kogelnik, Nora, Wintersperger, Andrea, Hammer, Astrid, Schlager, Stefanie, Jandl, Katharina, Heinemann, Akos, Kratky, Dagmar, Malle, Ernst, Sattler, Wolfgang
Publicado 2016

Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation

por Leopold, Christina, Duta-Mare, Madalina, Sachdev, Vinay, Goeritzer, Madeleine, Maresch, Lisa Katharina, Kolb, Dagmar, Reicher, Helga, Wagner, Bettina, Stojakovic, Tatjana, Ruelicke, Thomas, Haemmerle, Guenter, Hoefler, Gerald, Sattler, Wolfgang, Kratky, Dagmar
Publicado 2019

Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin

por Üllen, Andreas, Nusshold, Christoph, Glasnov, Toma, Saf, Robert, Cantillo, David, Eibinger, Gerald, Reicher, Helga, Fauler, Günter, Bernhart, Eva, Hallstrom, Seth, Kogelnik, Nora, Zangger, Klaus, Oliver Kappe, C., Malle, Ernst, Sattler, Wolfgang
Publicado 2015

Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro

por Goeritzer, Madeleine, Bernhart, Eva, Plastira, Ioanna, Reicher, Helga, Leopold, Christina, Eichmann, Thomas O., Rechberger, Gerald, Madreiter-Sokolowski, Corina T., Prasch, Jürgen, Eller, Philipp, Graier, Wolfgang F., Kratky, Dagmar, Malle, Ernst, Sattler, Wolfgang
Publicado 2020

2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells

por Bernhart, Eva, Kogelnik, Nora, Prasch, Jürgen, Gottschalk, Benjamin, Goeritzer, Madeleine, Depaoli, Maria Rosa, Reicher, Helga, Nusshold, Christoph, Plastira, Ioanna, Hammer, Astrid, Fauler, Günter, Malli, Roland, Graier, Wolfgang F., Malle, Ernst, Sattler, Wolfgang
Publicado 2018