GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecifi...

por Moelleken, Jörg, Endesfelder, Manuel, Gassner, Christian, Lingke, Sabine, Tomaschek, Simone, Tyshchuk, Oksana, Lorenz, Stefan, Reiff, Ulrike, Mølhøj, Michael
Publicado 2017

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

por Stracke, Jan, Emrich, Thomas, Rueger, Petra, Schlothauer, Tilman, Kling, Lothar, Knaupp, Alexander, Hertenberger, Hubert, Wolfert, Andreas, Spick, Christian, Lau, Wilma, Drabner, Georg, Reiff, Ulrike, Koll, Hans, Papadimitriou, Apollon
Publicado 2014